Search Results - "Miyashita, Sari"

Bone circuitry and interorgan skeletal crosstalk by Zaidi, Mone, Kim, Se-Min, Mathew, Mehr, Korkmaz, Funda, Sultana, Farhath, Miyashita, Sari, Gumerova, Anisa Azatovna, Frolinger, Tal, Moldavski, Ofer, Barak, Orly, Pallapati, Anusha, Rojekar, Satish, Caminis, John, Ginzburg, Yelena, Ryu, Vitaly, Davies, Terry F, Lizneva, Daria, Rosen, Clifford J, Yuen, Tony

“…The past decade has seen significant advances in our understanding of skeletal homeostasis and the mechanisms that mediate the loss of bone integrity in…”
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Brain atlas for glycoprotein hormone receptors at single-transcript level by Ryu, Vitaly, Gumerova, Anisa, Korkmaz, Funda, Kang, Seong Su, Katsel, Pavel, Miyashita, Sari, Kannangara, Hasni, Cullen, Liam, Chan, Pokman, Kuo, TanChun, Padilla, Ashley, Sultana, Farhath, Wizman, Soleil A, Kramskiy, Natan, Zaidi, Samir, Kim, Se-Min, New, Maria I, Rosen, Clifford J, Goosens, Ki A, Frolinger, Tal, Haroutunian, Vahram, Ye, Keqiang, Lizneva, Daria, Davies, Terry F, Yuen, Tony, Zaidi, Mone

“…There is increasing evidence that anterior pituitary hormones, traditionally thought to have unitary functions in regulating single endocrine targets, act on…”
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Antigenic variants of influenza B viruses isolated in Japan during the 2017‐2018 and 2018‐2019 influenza seasons by Kato‐Miyashita, Sari, Sakai‐Tagawa, Yuko, Yamashita, Makoto, Iwatsuki‐Horimoto, Kiyoko, Ito, Mutsumi, Tokita, Akifumi, Hagiwara, Haruhisa, Izumida, Naomi, Nishino, Tamon, Wada, Noriyuki, Koga, Michiko, Adachi, Eisuke, Jubishi, Daisuke, Yotsuyanagi, Hiroshi, Kawaoka, Yoshihiro, Imai, Masaki

“…Background Here, we genetically and antigenically analyzed influenza B viruses (IBVs) isolated in Japan during the 2017‐2018 and 2018‐2019 influenza seasons…”
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FSH blockade improves cognition in mice with Alzheimer’s disease by Xiong, Jing, Kang, Seong Su, Wang, Zhihao, Liu, Xia, Kuo, Tan-Chun, Korkmaz, Funda, Padilla, Ashley, Miyashita, Sari, Chan, Pokman, Zhang, Zhaohui, Katsel, Pavel, Burgess, Jocoll, Gumerova, Anisa, Ievleva, Kseniia, Sant, Damini, Yu, Shan-Ping, Muradova, Valeriia, Frolinger, Tal, Lizneva, Daria, Iqbal, Jameel, Goosens, Ki A., Gera, Sakshi, Rosen, Clifford J., Haroutunian, Vahram, Ryu, Vitaly, Yuen, Tony, Zaidi, Mone, Ye, Keqiang

“…Alzheimer’s disease has a higher incidence in older women, with a spike in cognitive decline that tracks with visceral adiposity, dysregulated energy…”
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Thyrotropin, Hyperthyroidism, and Bone Mass by Kim, Se-Min, Ryu, Vitaly, Miyashita, Sari, Korkmaz, Funda, Lizneva, Daria, Gera, Sakshi, Latif, Rauf, Davies, Terry F, Iqbal, Jameel, Yuen, Tony, Zaidi, Mone

“…Thyrotropin (TSH), traditionally seen as a pituitary hormone that regulates thyroid glands, has additional roles in physiology including skeletal remodeling…”
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Absent LH signaling rescues the anxiety phenotype in aging female mice by Sims, Steven, Barak, Orly, Ryu, Vitaly, Miyashita, Sari, Kannangara, Hasni, Korkmaz, Funda, Wizman, Soleil, Macdonald, Anne, Gumerova, Anisa, Goosens, Ki, Zaidi, Mone, Yuen, Tony, Lizneva, Daria, Frolinger, Tal

“…Clinical studies and experimental data together support a role for pituitary gonadotropins, including luteinizing hormone (LH), otherwise considered solely as…”
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Emerging roles of brain tanycytes in regulating blood–hypothalamus barrier plasticity and energy homeostasis by Kannangara, Hasni, Cullen, Liam, Miyashita, Sari, Korkmaz, Funda, Macdonald, Anne, Gumerova, Anisa, Witztum, Ronit, Moldavski, Ofer, Sims, Steven, Burgess, Jocoll, Frolinger, Tal, Latif, Rauf, Ginzburg, Yelena, Lizneva, Daria, Goosens, Ki, Davies, Terry F., Yuen, Tony, Zaidi, Mone, Ryu, Vitaly

“…Seasonal changes in food intake and adiposity in many animal species are triggered by changes in the photoperiod. These latter changes are faithfully…”
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First-in-class humanized FSH blocking antibody targets bone and fat by Gera, Sakshi, Sant, Damini, Haider, Shozeb, Korkmaz, Funda, Kuo, Tan-Chun, Mathew, Mehr, Perez-Pena, Helena, Xie, Honglin, Chend, Hao, Batista, Rogerio, Ma, Kejun, Cheng, Zhen, Hadelia, Elina, Robinson, Cemre, Macdonald, Anne, Miyashita, Sari, Williams, Anthony, Jebian, Gregory, Miyashita, Hirotaka, Gumerova, Anisa, Ievleva, Kseniia, Smith, Pinar, He, Jiahuan, Ryu, Vitaly, DeMambro, Victoria, Quinn, Matthew A., Meseck, Marcia, Kim, Se-Min, Kumar, T. Rajendra, Iqbal, Jameel, New, Maria I., Lizneva, Daria, Rosen, Clifford J., Hsueh, Aaron J., Yuen, Tony, Zaidi, Mone

“…Blocking the action of FSH genetically or pharmacologically in mice reduces body fat, lowers serum cholesterol, and increases bone mass, making an anti-FSH…”
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Optimizing a therapeutic humanized follicle‐stimulating hormone–blocking antibody formulation by protein thermal shift assay by Sant, Damini, Rojekar, Satish, Gera, Sakshi, Pallapati, Anusha R., Gimenez‐Roig, Judit, Kuo, Tan‐Chun, Padilla, Ashley, Korkmaz, Funda, Cullen, Liam, Chatterjee, Jiya, Shelly, Eleanor, Meseck, Marcia, Miyashita, Sari, Macdonald, Anne, Sultana, Farhath, Barak, Orly, Ryu, Vitaly, Kim, Se‐Min, Robinson, Cemre, Rosen, Clifford J., Caminis, John, Lizneva, Daria, Haider, Shozeb, Yuen, Tony, Zaidi, Mone

“…Biopharmaceutical products are formulated using several Food and Drug Administration (FDA) approved excipients within the inactive ingredient limit to maintain…”
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SAT600 Absent LH Signaling Rescues The Anxiety Phenotype In Aging Female Mice by Sims, Steven, Barak, Orly, Ryu, Vitaly, Miyashita, Sari, Kannangara, Hasni Suhasha, Korkmaz, Funda, Macdonald, Anne, Gumerova, Anisa, Goosens, Ki, Zaidi, Mone, Yuen, Tony, Lizneva, Daria, Frolinger, Tal

“…Abstract Disclosure: S. Sims: None. O. Barak: None. V. Ryu: None. S. Miyashita: None. H.S. Kannangara: None. F. Korkmaz: None. A. Macdonald: None. A. Gumerova:…”
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FSH-blocking therapeutic for osteoporosis by Gera, Sakshi, Kuo, Tan-Chun, Gumerova, Anisa Azatovna, Korkmaz, Funda, Sant, Damini, DeMambro, Victoria, Sudha, Karthyayani, Padilla, Ashley, Prevot, Geoffrey, Munitz, Jazz, Teunissen, Abraham, van Leent, Mandy M T, Post, Tomas G J M, Fernandes, Jessica C, Netto, Jessica, Sultana, Farhath, Shelly, Eleanor, Rojekar, Satish, Kumar, Pushkar, Cullen, Liam, Chatterjee, Jiya, Pallapati, Anusha, Miyashita, Sari, Kannangara, Hasni, Bhongade, Megha, Sengupta, Puja, Ievleva, Kseniia, Muradova, Valeriia, Batista, Rogerio, Robinson, Cemre, Macdonald, Anne, Hutchison, Susan, Saxena, Mansi, Meseck, Marcia, Caminis, John, Iqbal, Jameel, New, Maria I, Ryu, Vitaly, Kim, Se-Min, Cao, Jay J, Zaidi, Neeha, Fayad, Zahi A, Lizneva, Daria, Rosen, Clifford J, Yuen, Tony, Zaidi, Mone

“…Pharmacological and genetic studies over the past decade have established the follicle-stimulating hormone (FSH) as an actionable target for diseases affecting…”
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FRI001 Tanycytic Thyroid-stimulating Hormone Receptor Activation Increases Blood-Hypothalamus Barrier Permeability And Induces Appetite In Female Mice by Kannangara, Hasni Suhasha, Jocoll, Burgess, Miyashita, Sari, Gumerova, Anisa, Korkmaz, Funda, Witztum, Ronit, Sims, Steven, Cheliadinova, Uliana, Pevnev, Georgii, Moldavski, Ofer, Frolinger, Tal, Yuen, Tony, Ryu, Vitaly, Zaidi, Mone

“…Abstract Disclosure: H.S. Kannangara: None. B. Jocoll: None. S. Miyashita: None. A. Gumerova: None. F. Korkmaz: None. R. Witztum: None. S. Sims: None. U…”
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8631 Tanycytic TSHR Activation Regulates Blood-Hypothalamus Barrier Plasticity, Ingestive Behavior, Adipose Remodeling, and Body Weight by Cullen, Liam, Suhasha Kannangara, Hasni, Witztum, Ronit, Burgess, JoColl, Miyashita, Sari, Gumerova, Anisa, Korkmaz, Funda, Lee Sims, Steven, Cheliadinova, Uliana, Sultana, Farhath, Pevnev, Georgii, Moldavski, Ofer, Barak, Orly, Rojekar, Satish, Laurencin, Victoria, Frolinger, Tal, Yuen, Tony, Goosens, Ki, Zhou, Weibin, Ryu, Vitaly, Zaidi, Mone

“…Abstract Disclosure: L. Cullen: None. H.S. Kannangara: None. R. Witztum: None. J. Burgess: None. S. Miyashita: None. A. Gumerova: None. F. Korkmaz: None. S.L…”
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SAT668 Can We Treat Osteoporosis, Obesity And Neurodegeneration With A Single FSH-blocking Drug? by Rani Pallapati, Anusha Rani, Gimenez-Roig, Judit, Rojekar, Satish, Korkmaz, Funda, Sant, Damini, Barak, Orly, Sultana, Farhath, Moldavski, Ofer, Gumerova, Anisa, Kannangara, Hasni Suhasha, Cheliadinova, Uliana, Rosen, Clifford J, Caminis, John N, Meseck, Marcia, Demambro, Victoria Elise, Sims, Steven Lee, Gera, Sakshi, Witztum, Ronit, Miyashita, Sari, Ryu, Vitaly, Saxena, Mansi, Frolinger, Tal, Macdonald, Anne, Kim, Se-Min, Pevnev, Georgii, Lizneva, Daria, Yuen, Tony, Zaidi, Mone

“…Abstract Disclosure: A.R. Pallapati: None. J. Gimenez-Roig: None. S. Rojekar: None. F. Korkmaz: None. D. Sant: None. O. Barak: None. F. Sultana: None. O…”
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SAT669 Development And Biophysical Characterization Of A Humanized FSH-blocking Monoclonal Antibody Therapeutic Formulated At An Ultra-high Concentration by Rojekar, Satish, Pallapati, Anusha Rani, Gimenez–Roig, Judit, Sant, Damini, Gera, Sakshi, Korkmaz, Funda, Sultana, Farhath, Barak, Orly, Moldavski, Ofer, Cheliadinova, Uliana, Gumerova, Anisa Azatovna, Miyashita, Sari, Kannangara, Hasni Suhasha, Frolinger, Tal, Witztum, Ronit, Macdonald, Anne, Georgii, Pevnev, Sims, Steven Lee, Caminis, John N, Meseck, Marcia, Ryu, Vitaly, Kim, Se-Min, Lizneva, Daria, Yuen, Tony, Zaidi, Mone

“…Abstract Disclosure: S. Rojekar: None. A.R. Pallapati: None. J. Gimenez–Roig: None. D. Sant: None. S. Gera: None. F. Korkmaz: None. F. Sultana: None. O. Barak:…”
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PMON51 A Single Multipurpose FSH–Blocking Therapeutic for Osteoporosis, Obesity and Alzheimer's Disease by Korkmaz, Funda, Kuo, Tan-Chun, Gera, Sakshi, Sant, Damini, DeMambro, Victoria, Gumerova, Anisa, Sudha, Kathayani, Padilla, Ashley, Netto, Jessica, Sultana, Farhath, Miyashita, Sari, Shelly, Eleanor, Kumar, Pushkar, Burgess, Jocoll, Kannangara, Hasni, Muradova, Valeriia, Hutchison, Susan, Saxena, Mansi, Ryu, Vitaly, Kim, Se-Min, Meseck, Marcia, Goosens, Ki, Rosen, Cliff, Lizneva, Daria, Yuen, Tony, Zaidi, Mone

“…Abstract Pharmacological and genetic studies over the past decade suggest that FSH is an actionable target for diseases affecting millions, notably…”
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