Search Results - "Miyaoka, Hiroaki"

Total Synthesis of Chlorinated Oxylipin Eiseniachloride B by Ota, Koichiro, Kamaike, Kazuo, Miyaoka, Hiroaki

“…Eiseniachloride B is a marine chlorinated oxylipin isolated from the brown alga Eisenia bicyclis. This natural product contains cyclopentane, chlorohydrin, and…”
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Total Synthesis of Dinorsesquiterpenoid Oxyphyllin A/Belchinoid A by Ota, Koichiro, Kashima, Naoya, Fukaya, Haruhiko, Okazaki, Shinnosuke, Miyaoka, Hiroaki

“…Here, we report the first synthesis of oxyphyllin A/belchinoid A, a 7,9-seco-8,12-dinor-guaiane sesquiterpene whose isolation was reported independently by two…”
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Total Synthesis of Marine Polyketide Plakortone Q by Okazaki, Shinnosuke, Senda, Kaho, Tokuta, Ayaka, Inagaki, Misa, Kamaike, Kazuo, Ota, Koichiro, Miyaoka, Hiroaki

“…The total synthesis of the natural bicyclo[3.3.0]furanolactone polyketide, plakortone Q, was achieved in 24 steps from (R)-Roche ester. The main feature of…”
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Cigarette smoking is a risk factor for the onset of fatty liver disease in nondrinkers: A longitudinal cohort study by Okamoto, Masashi, Miyake, Teruki, Kitai, Kohichiro, Furukawa, Shinya, Yamamoto, Shin, Senba, Hidenori, Kanzaki, Sayaka, Deguchi, Akiko, Koizumi, Mitsuhito, Ishihara, Toru, Miyaoka, Hiroaki, Yoshida, Osamu, Hirooka, Masashi, Kumagi, Teru, Abe, Masanori, Matsuura, Bunzo, Hiasa, Yoichi

“…The effect of cigarette smoking on the onset of nonalcoholic fatty liver disease (NAFLD) is unclear, especially that associated with drinking small amounts of…”
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First total synthesis of (-)-sinularianin B by Ota, Koichiro, Miyaoka, Hiroaki

“…The first enantioselective total synthesis of (-)-sinularianin B, a structurally unique sesquiterpenoid isolated from the Formosan soft coral Sinularia sp.,…”
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Cordyceps militaris Fruit Body Extract Decreases Testosterone Catabolism and Testosterone-Stimulated Prostate Hypertrophy by Kusama, Kazuya, Miyagawa, Mayuko, Ota, Koichiro, Kuwabara, Naoko, Saeki, Kaori, Ohnishi, Yuki, Kumaki, Yasuhiro, Aizawa, Tomoyasu, Nakasone, Toyokazu, Okamatsu, Shigemi, Miyaoka, Hiroaki, Tamura, Kazuhiro

“…The androgens testosterone and dihydrotestosterone (DHT) are essential for a variety of systemic functions in mature males. Alteration of these hormones…”
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Total synthesis of antimalarial diterpenoid (+)-kalihinol A by Miyaoka, Hiroaki, Abe, Yasunori, Sekiya, Nobuaki, Mitome, Hidemichi, Kawashima, Etsuko

“…Total synthesis of antimalarial diterpenoid (+)-kalihinol A, isolated from marine sponge Acanthella sp., is achieved. This total synthesis involves…”
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Total Synthesis of Marine Sesquiterpenoid Sinularianin B and 8-epi-Sinularianin B by Miyaoka, Hiroaki, Ota, Koichiro

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Ipragliflozin ameliorates liver damage in non-alcoholic fatty liver disease by Miyake, Teruki, Yoshida, Sakiko, Furukawa, Shinya, Sakai, Takenori, Tada, Fujimasa, Senba, Hidenori, Yamamoto, Shin, Koizumi, Yohei, Yoshida, Osamu, Hirooka, Masashi, Kumagi, Teru, Niiya, Tetsuju, Miyaoka, Hiroaki, Masanori, Abe, Matsuura, Bunzo, Hiasa, Yoichi

“…There are few effective medications for non-alcoholic steatohepatitis (NASH). We investigated the efficacy of ipragliflozin (selective sodium-glucose…”
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Association between subclinical hypothyroidism and diabetic nephropathy in patients with type 2 diabetes mellitus by Furukawa, Shinya, Yamamoto, Shin, Todo, Yasuhiko, Maruyama, Kotatsu, Miyake, Teruki, Ueda, Teruhisa, Niiya, Tetsuji, Senba, Takatoshi, Torisu, Masamoto, Kumagi, Teru, Miyauchi, Syozo, Sakai, Takenori, Minami, Hisaka, Miyaoka, Hiroaki, Matsuura, Bunzo, Hiasa, Yoichi, Onji, Morikazu, Tanigawa, Takeshi

“…Subclinical hypothyroidism (SCH) has been associated with type 2 diabetes mellitus. However, it is unknown whether common complications of type 2 diabetes,…”
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Synthesis and Evaluation of MGB Polyamide-Oligonucleotide Conjugates as Gene Expression Control Compounds by Kamaike, Kazuo, Sano, Mutsumi, Sakata, Daisuke, Nishihara, Yu, Amino, Hiroaki, Ohtsuki, Akihiro, Okada, Yui, Miyakawa, Takafumi, Kogawara, Makoto, Tsutsumi, Mai, Takahashi, Misato, Kawashima, Etsuko, Ota, Koichiro, Miyaoka, Hiroaki

“…MGB polyamide-oligonucleotide conjugates ON 1-4 with linked MGB polyamides at the 2-exocyclic amino group of a guanine base using aminoalkyl linkers were…”
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Total Synthesis of Marine Eicosanoid (−)-Hybridalactone by Ota, Koichiro, Sugata, Naoto, Ohshiro, Yoshihiko, Kawashima, Etsuko, Miyaoka, Hiroaki

“…(−)‐Hybridalactone (1) is a marine eicosanoid isolated from the red alga Laurencia hybrida. This natural product contains cyclopropane, cyclopentane,…”
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Synthesis of Marine Diterpene Isocyanide (−)-Kalihinol Y and Diterpene Isothiocyanate (−)-10-Epi-kalihinol I by Miyaoka, Hiroaki, Abe, Yasunori, Kawashima, Etsuko

“…The authors described the first synthesis of diterpene isocyanide (−)-kalihinol Y and diterpene isothiocyanate (−)-10-epi-kalihinol I from synthetic…”
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Synthesis of the Diazepanone-Nucleoside Core Structure of Liposidomycins and Caprazamycins Based on 7-Exo Cyclization of Epoxyamine by Miyaoka, Hiroaki, Wada, Jumpei, Kawashima, Etsuko

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Synthesis of Phenol Derivatives from Cyclohex-2-enones Bearing an Alkyne through Lewis Acid-Catalyzed Enolization and Intramolecular Alder–Rickert Reaction by Kinbara, Atsushi, Yamagishi, Takehiro, Hanzawa, Naoko, Kawashima, Etsuko, Miyaoka, Hiroaki

“…A cationic rhodium­(I) complex- or In­(OTf)3-catalyzed synthesis of phenol derivatives from cyclohex-2-enone having an ethoxycarbonyl-substituted alkyne has…”
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B-type natriuretic peptide and renal function in Japanese patients with type 2 diabetes mellitus: The Dogo Study by Furukawa, Shinya, Sakai, Takenori, Niiya, Tetsuji, Miyaoka, Hiroaki, Miyake, Teruki, Yamamoto, Shin, Tanaka, Keiko, Ueda, Teruhisa, Senba, Hidenori, Torisu, Masamoto, Minami, Hisaka, Matsuura, Bunzo, Hiasa, Yoichi, Miyake, Yoshihiro

“…Among patients with type 2 diabetes mellitus, the association between B-type natriuretic peptide (BNP) and renal function remains controversial. We therefore…”
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Macrovascular Complications and Prevalence of Urgency Incontinence in Japanese Patients with Type 2 Diabetes Mellitus: The Dogo Study by Furukawa, Shinya, Sakai, Takenori, Niiya, Tetsuji, Miyaoka, Hiroaki, Miyake, Teruki, Yamamoto, Shin, Kanzaki, Sayaka, Maruyama, Koutatsu, Tanaka, Keiko, Ueda, Teruhisa, Senba, Hidenori, Torisu, Masamoto, Minami, Hisaka, Onji, Morikazu, Tanigawa, Takeshi, Matsuura, Bunzo, Hiasa, Yoichi, Miyake, Yoshihiro

“…Objective Macrovascular diseases and urgency incontinence are common among Japanese patients with type 2 diabetes mellitus. However, little evidence exists…”
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Fear of hypoglycemia and its determinants in insulin‐treated patients with type 2 diabetes mellitus by Sakane, Naoki, Kotani, Kazuhiko, Tsuzaki, Kokoro, Nishi, Masami, Takahashi, Kaoru, Murata, Takashi, Yamada, Kazunori, Okazaki, Kentaro, Yanagisawa, Katsuyuki, Yamada, Kenichi, Kuribayashi, Nobuichi, Totsuka, Yasuo, Hiyoshi, Toru, Naka, Motoji, Sugimoto, Masatake, Aoki, Yuji, Waki, Masako, Furuya, Miyuki, Kitaoka, Haruko, Oishi, Mariko, Shimizu, Ikki, Miyaoka, Hiroaki, Okada, Akira, Yamamoto, Toshikazu

“…The aim of the present study was to investigate the prevalence of fear of hypoglycemia, in association with severe hypoglycemia and social factors, in…”
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A Formal Synthesis of Antimalarial Diterpenoid 7,20-Diisocyanoadociane by Miyaoka, Hiroaki, Okubo, Yusuke, Muroi, Makiko, Mitome, Hidemichi, Kawashima, Etsuko

“…A formal synthesis of antimalarial diterpenoid 7,20-diisocyanoadociane, isolated from marine sponge Adocia sp., was achieved. The authors synthesized Corey’s…”
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Physical activity and prevalence of erectile dysfunction in Japanese patients with type 2 diabetes mellitus: The Dogo Study by Minami, Hisaka, Furukawa, Shinya, Sakai, Takenori, Niiya, Tetsuji, Miyaoka, Hiroaki, Miyake, Teruki, Yamamoto, Shin, Kanzaki, Sayaka, Maruyama, Koutatsu, Tanaka, Keiko, Ueda, Teruhisa, Senba, Hidenori, Torisu, Masamoto, Tanigawa, Takeshi, Matsuura, Bunzo, Hiasa, Yoichi, Miyake, Yoshihiro

“…Aims/Introduction To date, there is no evidence regarding the association between physical activity (PA) and erectile dysfunction (ED) among Japanese patients…”
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