Search Results - "Miyamoto, Licht"

Molecular Pathogenesis of Familial Wolff‐Parkinson‐White Syndrome: Molecular Mechanisms of Cardiac Glycogen Regulation by AMPK by Miyamoto, Licht

“…Familial Wolff‐Parkinson‐White (WPW) syndrome is an autosomal dominant inherited disease and consists of a small percentage of WPW syndrome which exhibits…”
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Indigo Leaves-Induced Pulmonary Arterial Remodeling without Right Ventricular Hypertrophy in Rats by Tsunematsu, Honoka, Imanishi, Masaki, Uemura, Yuka, Higaki, Yoshiya, Morisaki, Miyu, Katsura, Akari, Miyamoto, Licht, Funamoto, Masafumi, Ichimura-Shimizu, Mayuko, Horinouchi, Yuya, Ikeda, Yasumasa, Tsuneyama, Koichi, Tsuchiya, Koichiro

“…Indigo naturalis (IN), derived from the leaves of the indigo plant, is a traditional Chinese medicine that has historically been used for its anti-inflammatory…”
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Can food factors provide Us with the similar beneficial effects of physical exercise? by Miyamoto, Licht

“…Metabolic diseases have got global health issues. Physical exercise as well as diet therapy is a potent strategy for fighting against the diseases. However, it…”
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Novel Strategies for Treating Lifestyle-related Diseases Using Various Approaches by Miyamoto, Licht

“…The number of patients with metabolic disorders is dramatically increasing all over the world. The diseases often exhibit multiple metabolic disturbances…”
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Mechanisms of the pH- and Oxygen-Dependent Oxidation Activities of Artesunate by Tsuda, Katsunori, Miyamoto, Licht, Hamano, Shuichi, Morimoto, Yuri, Kangawa, Yumi, Fukue, Chika, Kagawa, Yoko, Horinouchi, Yuya, Xu, Wenting, Ikeda, Yasumasa, Tamaki, Toshiaki, Tsuchiya, Koichiro

“…Artemisinin was discovered in 1971 as a constituent of the wormwood genus plant (Artemisia annua). This plant has been used as an herbal medicine to treat…”
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Changes in intestinal microbiota and biochemical parameters in patients with inflammatory bowel disease and irritable bowel syndrome induced by the prolonged addition of soluble fibers to usual drug therapy by Watanabe, Hideo, Inoue, Takahisa, Miyamoto, Licht, Ono, Yoshito, Matsumoto, Kinya, Takeda, Masanori, Tsuchiya, Koichiro

“…Objectives:Partially hydrolyzed guar gum (PHGG) is a soluble dietary fiber;in addition to improving bowel movements, it maintains intestinal health by…”
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Iron chelation by deferoxamine prevents renal interstitial fibrosis in mice with unilateral ureteral obstruction by Ikeda, Yasumasa, Ozono, Iori, Tajima, Soichiro, Imao, Mizuki, Horinouchi, Yuya, Izawa-Ishizawa, Yuki, Kihira, Yoshitaka, Miyamoto, Licht, Ishizawa, Keisuke, Tsuchiya, Koichiro, Tamaki, Toshiaki

“…Renal fibrosis plays an important role in the onset and progression of chronic kidney diseases (CKD). Although several mechanisms underlying renal fibrosis and…”
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Proton pump inhibitors block iron absorption through direct regulation of hepcidin via the aryl hydrocarbon receptor-mediated pathway by Hamano, Hirofumi, Niimura, Takahiro, Horinouchi, Yuya, Zamami, Yoshito, Takechi, Kenshi, Goda, Mitsuhiro, Imanishi, Masaki, Chuma, Masayuki, Izawa-Ishizawa, Yuki, Miyamoto, Licht, Fukushima, Keijo, Fujino, Hiromichi, Tsuchiya, Koichiro, Ishizawa, Keisuke, Tamaki, Toshiaki, Ikeda, Yasumasa

“…•Proton pump inhibitors increase the risk of developing iron deficiency.•Omeprazole enhances the expression of hepcidin via aryl hydrocarbon receptor…”
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Metabolic beneficial effects of Citrus Sudachi by Miyamoto, Licht, Tsuchiya, Koichiro

“…Sudachi (Citrus Sudachi) is a sour fruit and is a popular seasoning for Japanese dishes, Washoku. It can grow only in Tokushima and the surrounding areas for…”
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Lifestyle Inspires Future Pharmacotherapy and Drug Discovery by Miyamoto, Licht, Nishida, Motohiro

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Deletion of H-ferritin in macrophages alleviates obesity and diabetes induced by high-fat diet in mice by Ikeda, Yasumasa, Watanabe, Hiroaki, Shiuchi, Tetsuya, Hamano, Hirofumi, Horinouchi, Yuya, Imanishi, Masaki, Goda, Mitsuhiro, Zamami, Yoshito, Takechi, Kenshi, Izawa-Ishizawa, Yuki, Miyamoto, Licht, Ishizawa, Keisuke, Aihara, Ken-ichi, Tsuchiya, Koichiro, Tamaki, Toshiaki

“…Aims/hypothesis Iron accumulation affects obesity and diabetes, both of which are ameliorated by iron reduction. Ferritin, an iron-storage protein, plays a…”
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Antitumor effect of novel anti‐podoplanin antibody NZ‐12 against malignant pleural mesothelioma in an orthotopic xenograft model by Abe, Shinji, Kaneko, Mika Kato, Tsuchihashi, Yuki, Izumi, Toshihiro, Ogasawara, Satoshi, Okada, Naoto, Sato, Chiemi, Tobiume, Makoto, Otsuka, Kenji, Miyamoto, Licht, Tsuchiya, Koichiro, Kawazoe, Kazuyoshi, Kato, Yukinari, Nishioka, Yasuhiko

“…Podoplanin (aggrus) is highly expressed in several types of cancers, including malignant pleural mesothelioma (MPM). Previously, we developed a rat anti‐human…”
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Novel Hydrophilic Camptothecin Derivatives Conjugated to Branched Glycerol Trimer Suppress Tumor Growth without Causing Diarrhea in Murine Xenograft Models of Human Lung Cancer by Tsuchihashi, Yuki, Abe, Shinji, Miyamoto, Licht, Tsunematsu, Honoka, Izumi, Toshihiro, Hatano, Aya, Okuno, Hiroko, Yamane, Megumi, Yasuoka, Takashi, Ikeda, Yasumasa, Tsuchiya, Koichiro

“…Camptothecin possesses broad antitumor spectra on various cancers. In spite of its marked tumor-suppressing potency, camptothecin is too hydrophobic to be…”
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Nitrite Activates 5′AMP-Activated Protein Kinase-Endothelial Nitric Oxide Synthase Pathway in Human Glomerular Endothelial Cells by Miyamoto, Licht, Yamane, Megumi, Tomida, Yosuke, Kono, Mai, Yamaoka, Tomomi, Kawasaki, Aya, Hatano, Aya, Tsuda, Katsunori, Xu, Wenting, Ikeda, Yasumasa, Tamaki, Toshiaki, Tsuchiya, Koichiro

“…Recent studies have shown that orally supplied nitrates, which substantially exist in our daily diets, are reduced into nitrites and become significant sources…”
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Renoprotective effects of a factor Xa inhibitor: fusion of basic research and a database analysis by Horinouchi, Yuya, Ikeda, Yasumasa, Fukushima, Keijo, Imanishi, Masaki, Hamano, Hirofumi, Izawa-Ishizawa, Yuki, Zamami, Yoshito, Takechi, Kenshi, Miyamoto, Licht, Fujino, Hiromichi, Ishizawa, Keisuke, Tsuchiya, Koichiro, Tamaki, Toshiaki

“…Renal tubulointerstitial injury, an inflammation-associated condition, is a major cause of chronic kidney disease (CKD). Levels of activated factor X (FXa), a…”
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Nitrite Activates 5'AMP-Activated Protein Kinase-Endothelial Nitric Oxide Synthase Pathway in Human Glomerular Endothelial Cells by Miyamoto, Licht, Yamane, Megumi, Tomida, Yosuke, Kono, Mai, Yamaoka, Tomomi, Kawasaki, Aya, Hatano, Aya, Tsuda, Katsunori, Xu, Wenting, Ikeda, Yasumasa, Tamaki, Toshiaki, Tsuchiya, Koichiro

“…Recent studies have shown that orally supplied nitrates, which substantially exist in our daily diets, are reduced into nitrites and become significant sources…”
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Significance of 5’AMP-activated protein kinase in metabolomic regulation by skeletal muscle contraction by Licht Miyamoto

“…The number of patients exhibiting metabolic disorders has been pandemically increasing. Physical exercise is widely applied as an ideal therapeutic and…”
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Dietary iron restriction alleviates renal tubulointerstitial injury induced by protein overload in mice by Ikeda, Yasumasa, Horinouchi, Yuya, Hamano, Hirofumi, Hirayama, Tasuku, Kishi, Seiji, Izawa-Ishizawa, Yuki, Imanishi, Masaki, Zamami, Yoshito, Takechi, Kenshi, Miyamoto, Licht, Ishizawa, Keisuke, Aihara, Ken-ichi, Nagasawa, Hideko, Tsuchiya, Koichiro, Tamaki, Toshiaki

“…Increased proteinuria causes tubulointerstitial injury due to inflammation in chronic kidney disease (CKD). Iron restriction exhibits protective effects…”
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AICAR stimulation metabolome widely mimics electrical contraction in isolated rat epitrochlearis muscle by Miyamoto, Licht, Egawa, Tatsuro, Oshima, Rieko, Kurogi, Eriko, Tomida, Yosuke, Tsuchiya, Koichiro, Hayashi, Tatsuya

“…Physical exercise has potent therapeutic and preventive effects against metabolic disorders. A number of studies have suggested that 5'-AMP-activated protein…”
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Methanol extraction fraction from Citrus Sudachi peel exerts lipid reducing effects in cultured cells by Xu, Wenting, Miyamoto, Licht, Aihara, Haruna, Yamaoka, Tomomi, Tanaka, Naonobu, Tsuchihashi, Yuki, Ikeda, Yasumasa, Tamaki, Toshiaki, Kashiwada, Yoshiki, Tsuchiya, Koichiro

“…Ectopic fat accumulation is associated with insulin resistance and type 2 diabetes mellitus. Citrus sudachi is an evergreen tree that is found mainly in…”
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