Search Results - "Miyamoto, Kenichi"

Cutting Edge Molecular Therapy for Acute Myeloid Leukemia by Miyamoto, Kenichi, Minami, Yosuke

“…Recently, whole exome sequencing for acute myeloid leukemia (AML) has been performed by a next-generation sequencer in several studies. It has been revealed…”
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Precision medicine and novel molecular target therapies in acute myeloid leukemia: the background of hematologic malignancies (HM)-SCREEN-Japan 01 by Miyamoto, Kenichi, Minami, Yosuke

“…The development of allogeneic hematopoietic-stem-cell transplantation has improved the prognosis of younger acute myeloid leukemia (AML) patients. However, the…”
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Comparison of the Bone Regenerative Capacity of Three-Dimensional Uncalcined and Unsintered Hydroxyapatite/Poly-d/l-Lactide and Beta-Tricalcium Phosphate Used as Bone Graft Substitutes by Bai, Yunpeng, Sha, Jingjing, Kanno, Takahiro, Miyamoto, Kenichi, Hideshima, Katsumi, Matsuzaki, Yumi

“…This study compared the in vivo applicability of three-dimensional uncalcined and unsintered hydroxyapatite/poly-d/l-lactide (3D-HA/PDLLA) with beta-tricalcium…”
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Application of a Bioactive/Bioresorbable Three-Dimensional Porous Uncalcined and Unsintered Hydroxyapatite/Poly-D/L-lactide Composite with Human Mesenchymal Stem Cells for Bone Regeneration in Maxillofacial Surgery: A Pilot Animal Study by Sha, Jingjing, Kanno, Takahiro, Miyamoto, Kenichi, Bai, Yunpeng, Hideshima, Katsumi, Matsuzaki, Yumi

“…A novel three-dimensional (3D) porous uncalcined and unsintered hydroxyapatite/poly-d/l-lactide (3D-HA/PDLLA) composite demonstrated superior biocompatibility,…”
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Comparison of the International Workshop Criteria and the Response Evaluation Criteria in Solid Tumors for indolent B-cell lymphoma by Miyamoto, Kenichi, Watanabe, Takashi, Wakabayashi, Masashi, Nakamura, Kenichi, Watanabe, Yuko, Maruyama, Dai, Tobinai, Kensei, Tsukasaki, Kunihiro, Fukuda, Haruhiko

“…Background [ 18 F] fluorodeoxyglucose-positron emission tomography is incorporated in response criteria currently used for lymphoma; however, the primary…”
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HLA genotyping in Japanese patients with multiple myeloma receiving bortezomib: An exploratory biomarker study of JCOG1105 (JCOG1105A1) by Ri, Masaki, Iida, Shinsuke, Maruyama, Dai, Sakabe, Aya, Kamei, Ryo, Nakashima, Takuto, Tohkin, Masahiro, Osaga, Satoshi, Tobinai, Kensei, Fukuhara, Noriko, Miyazaki, Kana, Tsukamoto, Norifumi, Tsujimura, Hideki, Yoshimitsu, Makoto, Miyamoto, Kenichi, Tsukasaki, Kunihiro, Nagai, Hirokazu

“…Bortezomib (Btz) shows robust efficacy in patients with multiple myeloma (MM); however, some patients experience suboptimal responses and show specific…”
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Chronic myeloid leukemia stem cells and molecular target therapies for overcoming resistance and disease persistence by Inoue, Ai, Kobayashi, Chiharu I., Shinohara, Haruka, Miyamoto, Kenichi, Yamauchi, Nobuhiko, Yuda, Junichiro, Akao, Yukihiro, Minami, Yosuke

“…Chronic myeloid leukemia (CML) is effectively treated with tyrosine kinase inhibitors (TKI) targeted against BCR-ABL. We previously reported the investigation…”
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Stage III disease of ovarian, tubal and peritoneal cancers can be accurately diagnosed with pre-operative CT. Japan Clinical Oncology Group Study JCOG0602 by Onda, Takashi, Tanaka, Yumiko Oishi, Kitai, Satomi, Manabe, Tomoko, Ishikawa, Mitsuya, Hasumi, Yoko, Miyamoto, Kenichi, Ogawa, Gakuto, Satoh, Toyomi, Saito, Toshiaki, Kasamatsu, Takahiro, Nakanishi, Toru

“…Abstract Purpose Computed tomography of the abdomen and pelvis is a useful imaging modality for identifying origin and extent of ovarian cancer before primary…”
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Endoplasmic Reticulum Stress Inhibits STAT3-Dependent Suppression of Hepatic Gluconeogenesis via Dephosphorylation and Deacetylation by KIMURA, Kumi, YAMADA, Tomoko, MIYAMOTO, Kenichi, KANEKO, Shuichi, KASUGA, Masato, INOUE, Hiroshi, MATSUMOTO, Michihiro, KIDO, Yoshiaki, HOSOOKA, Tetsuya, ASAHARA, Shun-Ichiro, MATSUDA, Tomokazu, OTA, Tsuguhito, WATANABE, Hiroshi, SAI, Yoshimichi

“…In the liver, signal transducer and activator of transcription 3 (STAT3) plays an important role in the suppression of gluconeogenic enzyme expression. While…”
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Study risk assessment of Japan Clinical Oncology Group (JCOG) clinical trials using the European Organisation for Research and Treatment of Cancer (EORTC) study risk calculator by Miyamoto, Kenichi, Nakamura, Kenichi, Mizusawa, Junki, de Balincourt, Christine, Fukuda, Haruhiko

“…New Japanese ethical guidelines for medical researches and the Clinical Trials Act have come into effect and monitoring is mandated for intervention studies…”
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Feasibility of a Three-Dimensional Porous Uncalcined and Unsintered Hydroxyapatite/poly-d/l-lactide Composite as a Regenerative Biomaterial in Maxillofacial Surgery by Bai, Yunpeng, Kanno, Takahiro, Tatsumi, Hiroto, Miyamoto, Kenichi, Sha, Jingjing, Hideshima, Katsumi, Matsuzaki, Yumi

“…This study evaluated the feasibility of a novel three-dimensional (3D) porous composite of uncalcined and unsintered hydroxyapatite (u-HA) and poly-d/l-lactide…”
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Bortezomib plus dexamethasone vs thalidomide plus dexamethasone for relapsed or refractory multiple myeloma by Iida, Shinsuke, Wakabayashi, Masashi, Tsukasaki, Kunihiro, Miyamoto, Kenichi, Maruyama, Dai, Yamamoto, Kazuhito, Takatsuka, Yoshifusa, Kusumoto, Shigeru, Kuroda, Junya, Ando, Kiyoshi, Kikukawa, Yoshitaka, Masaki, Yasufumi, Kobayashi, Miki, Hanamura, Ichiro, Asai, Hiroaki, Nagai, Hirokazu, Shimada, Kazuyuki, Tsukamoto, Norifumi, Inoue, Yoshiko, Tobinai, Kensei

“…A randomized phase II selection design study (JCOG0904) was carried out to evaluate the more promising regimen between bortezomib (Bor) plus dexamethasone…”
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SASPase regulates stratum corneum hydration through profilaggrin‐to‐filaggrin processing by Matsui, Takeshi, Miyamoto, Kenichi, Kubo, Akiharu, Kawasaki, Hiroshi, Ebihara, Tamotsu, Hata, Kazuya, Tanahashi, Shinya, Ichinose, Shizuko, Imoto, Issei, Inazawa, Johji, Kudoh, Jun, Amagai, Masayuki

“…The stratum corneum (SC), the outermost layer of the epidermis, acts as a barrier against the external environment. It is hydrated by endogenous humectants to…”
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A Phase III trial of a single early intravesical instillation of pirarubicin to prevent bladder recurrence after radical nephroureterectomy for upper tract urothelial carcinoma (JCOG1403, UTUC THP Phase III) by Miyamoto, Kenichi, Ito, Akihiro, Wakabayashi, Masashi, Eba, Junko, Arai, Yoichi, Nishiyama, Hiroyuki, Sugimoto, Mikio, Yamashita, Ryo, Kakehi, Yoshiyuki

“…This Phase III study commenced in October 2016 to investigate the superiority of intravesical pirarubicin instillation, versus observation, after radical…”
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Generation of a BAC transgenic mouse strain that expresses CreERT and a fluorescent protein under the transcriptional control of the Fzd5 locus by Miyagi, Satoru, Kato, Yuko, Watanabe, Ayako, Miyamoto, Kenichi, Yoshikawa, Rintaro, Hagiya, Keita, Hirano, Daisuke, Matsuzaki, Yumi

“…The expression of FZD5 distinguishes immature human mesenchymal stem/stromal cells (MSC) in cultures, and the function of FZD5 is crucial for maintaining the…”
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Efficacy of aspirin for stage III colorectal cancer: a randomized double-blind placebo-controlled trial (JCOG1503C, EPISODE-III trial) by Miyamoto, Kenichi, Takashima, Atsuo, Mizusawa, Junki, Sato, Yuya, Shimada, Yasuhiro, Katayama, Hiroshi, Nakamura, Kenichi, Shibata, Taro, Fukuda, Haruhiko, Shida, Dai, Kanemitsu, Yukihide, Hamaguchi, Tetsuya

“…Adjuvant chemotherapy is the current standard treatment for stage III colorectal cancer after curative resection. However, the prognosis of stage III…”
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Notch2 Signaling Regulates the Proliferation of Murine Bone Marrow-Derived Mesenchymal Stem/Stromal Cells via c-Myc Expression by Sato, Yukio, Mabuchi, Yo, Miyamoto, Kenichi, Araki, Daisuke, Niibe, Kunimichi, Houlihan, Diarmaid D, Morikawa, Satoru, Nakagawa, Taneaki, Nakajima, Toshihiro, Akazawa, Chihiro, Hori, Shingo, Okano, Hideyuki, Matsuzaki, Yumi

“…Mesenchymal stem/stromal cells (MSCs) reside in the bone marrow and maintain their stemness under hypoxic conditions. However, the mechanism underlying the…”
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Phase III study of watchful waiting vs. rituximab as first-line treatment in advanced stage follicular lymphoma with low tumour burden (JCOG1411, FLORA study) by Miyamoto, Kenichi, Fukuhara, Noriko, Maruyama, Dai, Shibata, Taro, Nakamura, Kenichi, Ishizawa, Kenichi, Tsukasaki, Kunihiro, Nagai, Hirokazu

“…A randomized phase III trial comparing watchful waiting with first-line rituximab for advanced stage follicular lymphoma commenced in Japan in December 2016…”
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Comparison of survival between upfront primary debulking surgery versus neoadjuvant chemotherapy for stage III/IV ovarian, tubal and peritoneal cancers in phase III randomized trial: JCOG0602 by ONDA, Takashi, Satoh, Toyomi, Saito, Toshiaki, Kasamatsu, Takahiro, Nakanishi, Toru, Takehara, Kazuhiro, Miyamoto, Kenichi, Wakabayashi, Masashi, Okamoto, Aikou, Ushijima, Kimio, Kobayashi, Hiroaki, Kawana, Kei, Yokota, Harushige, Takano, Masashi, Omatsu, Kohei, Watanabe, Yoh, Yamamoto, Kaichiro, Yaegashi, Nobuo, Kamura, Toshiharu, Yoshikawa, Hiroyuki

“…Abstract only…”
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Feasibility of Application of the Newly Developed Nano-Biomaterial, β-TCP/PDLLA, in Maxillofacial Reconstructive Surgery: A Pilot Rat Study by Toda, Erina, Bai, Yunpeng, Sha, Jingjing, Dong, Quang Ngoc, Ngo, Huy Xuan, Suyama, Takashi, Miyamoto, Kenichi, Matsuzaki, Yumi, Kanno, Takahiro

“…This study was performed to examine the applicability of the newly developed nano-biocomposite, β-tricalcium phosphate (β-TCP)/u-HA/poly-d/l-lactide (PDLLA),…”
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