Search Results - "Miyake, Yuka"

Prevalence and risk factors of internet gaming disorder and problematic internet use before and during the COVID-19 pandemic: A large online survey of Japanese adults by Oka, Taiki, Hamamura, Toshitaka, Miyake, Yuka, Kobayashi, Nao, Honjo, Masaru, Kawato, Mitsuo, Kubo, Takatomi, Chiba, Toshinori

“…Internet gaming disorder (IGD) and problematic internet use (PIU) are becoming increasingly detrimental to modern society, with serious consequences for daily…”
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Design, Synthesis, and Biological Evaluation of Lysine Demethylase 5 C Degraders by Iida, Tetsuya, Itoh, Yukihiro, Takahashi, Yukari, Yamashita, Yasunobu, Kurohara, Takashi, Miyake, Yuka, Oba, Makoto, Suzuki, Takayoshi

“…Lysine demethylase 5 C (KDM5C) controls epigenetic gene expression and is attracting great interest in the field of chemical epigenetics. KDM5C has emerged as…”
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Metalloprotein-Catalyzed Click Reaction for In Situ Generation of a Potent Inhibitor by Miyake, Yuka, Itoh, Yukihiro, Suzuma, Yoshinori, Kodama, Hidehiko, Kurohara, Takashi, Yamashita, Yasunobu, Narozny, Remy, Hanatani, Yutaro, Uchida, Shusaku, Suzuki, Takayoshi

“…In situ click chemistry has great potential for identifying enzyme inhibitors. However, conventional in situ click chemistry provides extremely low yields of…”
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Identification of Proteolysis Targeting Chimeras (PROTACs) for Lysine Demethylase 5 and Their Neurite Outgrowth-Promoting Activity by Iida, Tetsuya, Itoh, Yukihiro, Takahashi, Yukari, Miyake, Yuka, Zamani, Farzad, Yamashita, Yasunobu, Takada, Yuri, Akiyama, Toshiki, Ibaraki, Jun, Okuda, Kyoka, Tokuda, Yuto, Nishimura, Tomoka, Hidaka, Koto, Mori, Hiiro, Oba, Makoto, Suzuki, Takayoshi

“…Lysine demethylase 5 (KDM5) proteins are involved in various neurological disorders, including Alzheimer’s disease, and KDM5 inhibition is expected to be a…”
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Multiple time measurements of multidimensional psychiatric states from immediately before the COVID-19 pandemic to one year later: a longitudinal online survey of the Japanese population by Oka, Taiki, Kubo, Takatomi, Kobayashi, Nao, Nakai, Fumiya, Miyake, Yuka, Hamamura, Toshitaka, Honjo, Masaru, Toda, Hiroyuki, Boku, Shuken, Kanazawa, Tetsufumi, Nagamine, Masanori, Cortese, Aurelio, Takebayashi, Minoru, Kawato, Mitsuo, Chiba, Toshinori

“…The coronavirus disease 2019 (COVID-19) pandemic has profoundly affected the mental health of both infected and uninfected people. Although most psychiatric…”
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Impact of preoperative factors on catheter position in peritoneal dialysis: a prospective cohort study by Hoshino, Kento, Anan, Go, Hirose, Takuo, Yamakoshi, Seiko, Tajima, Ryo, Sato, Toshihiro, Miyake, Yuka, Fukunaga, Tsugumi, Kato, Toshiko, Endo, Akari, Seki, Takayuki, Nakayama, Shingo, Oba-Yabana, Ikuko, Nakamura, Hannah, Tani, Junichi, Mori, Takefumi

“…Background Peritoneal dialysis (PD) catheter malposition is one of the complications of renal replacement therapy. This study aimed to determine the…”
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Actomyosin tension is required for correct recruitment of adherens junction components and zonula occludens formation by Miyake, Yuka, Inoue, Naoko, Nishimura, Koji, Kinoshita, Nagatoki, Hosoya, Hiroshi, Yonemura, Shigenobu

“…The adherens junction (AJ) densely associated with actin filaments is a major cell–cell adhesion structure. To understand the importance of actin filament…”
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Depositional age of the Himenoura Group on the Amakusa‐Kamishima area, Kyushu, southwest Japan: Using zircon U–Pb dating of the acidic tuffs by Tsutsumi, Yukiyasu, Miyake, Yuka, Komatsu, Toshifumi

“…The Upper Cretaceous Himenoura Group in the Amakusa‐Kamishima Island area, southwest Japan is subdivided into the Hinoshima and Amura Formations. In order to…”
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Safety of peritoneal dialysis catheter surgery under dexmedetomidine and local anesthesia for elderly patients in Japan: a single-center prospective cohort study by Fukunaga, Tsugumi, Anan, Go, Hirose, Takuo, Miyake, Yuka, Hoshino, Kento, Endo, Akari, Tajima, Ryo, Ito, Hiroki, Nakayama, Shingo, Hashimoto, Hideaki, Ishiyama, Katsuya, Kimura, Tomoyoshi, Mori, Takefumi

“…Background The number of patients aged ≥ 75 years and who need renal replacement therapy is steadily increasing. The study aimed to determine the safety of…”
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The Impact of Preoperative Risk Factors on Peritoneal Dialysis-Related Peritonitis: A Single-Center Prospective Study in Japan by Sato, Toshihiro, Anan, Go, Hirose, Takuo, Tajima, Ryo, Hoshino, Kento, Miyake, Yuka, Fukunaga, Tsugumi, Kato, Toshiko, Endo, Akari, Ito, Hiroki, Nakayama, Shingo, Hashimoto, Hideaki, Ishiyama, Katsuya, Kimura, Tomoyoshi, Mori, Takefumi

“…: Peritoneal dialysis (PD)-related peritonitis is a critical problem. However, preoperative risk factors for PD-related peritonitis have not been established…”
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Endoplasmic Reticulum Protein (ERp) 29 Binds As Strongly As Protein Disulfide Isomerase (PDI) to Bisphenol A by Miyake, Yuka, Hashimoto, Shoko, Sasaki, Yoshie, Kudo, Tomohiro, Oguro, Ami, Imaoka, Susumu

“…Bisphenol A (BPA), which is used in polycarbonate and epoxy resins, affects the development or function of the central nervous system. Previously, we isolated…”
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Fabry Nephropathy in a Young Female Patient Presenting with Only Urinary Mulberry Bodies Treated with Chaperone Therapy by Fukunaga, Tsugumi, Nakayama, Shingo, Hirose, Takuo, Muramatsu, Kishin, Endo, Akari, Miyake, Yuka, Anan, Go, Oba-Yabana, Ikuko, Kanno, Atsuhiro, Nakamura, Hannah, Tani, Junichi, Nakamura, Kimitoshi, Sumitomo, Kazuhiro, Yumura, Wako, Furukawa, Katsutoshi, Mori, Takefumi

“…Fabry disease (FD) is an X-linked disorder of the sphingolipid metabolism, caused by deficiency or decreased activity of α-galactosidase A. We report a rare…”
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Pharmacokinetics of Chiral Dendrimer-Triamine-Coordinated Gd-MRI Contrast Agents Evaluated by in Vivo MRI and Estimated by in Vitro QCM by Miyake, Yuka, Ishikawa, Syungo, Kimura, Yu, Son, Aoi, Imai, Hirohiko, Matsuda, Tetsuya, Yamada, Hisatsugu, Toshimitsu, Akio, Kondo, Teruyuki

“…Recently, we developed novel chiral dendrimer-triamine-coordinated Gd-MRI contrast agents (Gd-MRI CAs), which showed longitudinal relaxivity (r₁) values about…”
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A case of light chain (AL) amyloidosis with heart failure, renal dysfunction, and heparin-induced thrombocytopenia successfully treated with peritoneal dialysis by Nakayama, Shingo, Kinugasa, Satoshi, Hirose, Takuo, Miyake, Yuka, Ota, Kohei, Onzo-Toyama, Maya, Oba-Yabana, Ikuko, Nakamura, Hannah, Tani, Junichi, Yumura, Wako, Mori, Takefumi

“…A 65-year-old woman was hospitalized for heart failure and pneumonia in a nearby hospital. She had been previously diagnosed as light chain (AL) amyloidosis…”
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The role of asparagine-linked glycosylation site on the catalytic domain of matriptase in its zymogen activation by Miyake, Yuka, Tsuzuki, Satoshi, Mochida, Seiya, Fushiki, Tohru, Inouye, Kuniyo

“…Matriptase is a type II transmembrane serine protease containing one potential site for asparagine-linked glycosylation (N-glycosylation) on the catalytic…”
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Activation of a Membrane-Bound Serine Protease Matriptase on the Cell Surface by Miyake, Yuka, Yasumoto, Makoto, Tsuzuki, Satoshi, Fushiki, Tohru, Inouye, Kuniyo

“…Matriptase is a type II transmembrane serine protease. The activation (i.e. conversion of the single-chain pro-form to the disulphide-linked-two-chain active…”
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Anterior cruciate ligament insertion after partial tear: histological changes and chondrocyte turnover by Sakane, Masataka, Mutsuzaki, Hirotaka, Nakajima, Hiromi, Hattori, Shinya, Shirozu, Yoshinori, Miyake, Yuka, Ochiai, Naoyuki

“…Purpose The purpose of this study was to clarify the effects of partial resection on the glycosaminoglycan (GAG) layer thicknesses and chondrocyte turnover…”
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The Structural Requirements of Matriptase in Its Ectodomain Release in Polarized Epithelial Cells by TSUZUKI, Satoshi, MURAI, Nobuhito, MIYAKE, Yuka, INOUYE, Kuniyo, FUSHIKI, Tohru

“…Matriptase is a type-II transmembrane serine protease abundantly expressed in polarized epithelia. The ectodomain of matriptase is released from the cell…”
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Synthesis and functional evaluation of chiral dendrimer–triamine-coordinated Gd complexes as highly sensitive MRI contrast agents by Miyake, Yuka, Kimura, Yu, Ishikawa, Syungo, Tsujita, Hiroshi, Miura, Hiroki, Narazaki, Michiko, Matsuda, Tetsuya, Tabata, Yasuhiko, Yano, Tetsuya, Toshimitsu, Akio, Kondo, Teruyuki

“…Novel chiral dendrimer–triamine-coordinated Gd complexes were synthesized and shown to have longitudinal relaxivity (r1) 3 times higher than that of clinically…”
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Matriptase does not require hepatocyte growth factor activator inhibitor type-1 for activation in an epithelial cell expression model by Miyake, Y., Kyoto Univ. (Japan), Tsuzuki, S, Fushiki, T, Inouye, K

“…Matriptase is a type II transmembrane serine protease. Paradoxically, activation of this protease is thought to require its physiological inhibitor, hepatocyte…”
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