Search Results - "Miwa, Takeshi"

Isoform switch of CD44 induces different chemotactic and tumorigenic ability in gallbladder cancer by Miwa, Takeshi, Nagata, Takuya, Kojima, Hirofumi, Sekine, Shinichi, Okumura, Tomoyuki

“…Gallbladder cancer (GBC) is one of the most unfavorable prognostic tumor, and immediate growth and distant metastasis are important factors associated with the…”
Get full text

Suppression of MicroRNA-7 (miR-7) Biogenesis by Nuclear Factor 90-Nuclear Factor 45 Complex (NF90-NF45) Controls Cell Proliferation in Hepatocellular Carcinoma by Higuchi, Takuma, Todaka, Hiroshi, Sugiyama, Yasunori, Ono, Masafumi, Tamaki, Nobuyuki, Hatano, Etsuro, Takezaki, Yuka, Hanazaki, Kazuhiro, Miwa, Takeshi, Lai, Sylvia, Morisawa, Keiko, Tsuda, Masayuki, Taniguchi, Taketoshi, Sakamoto, Shuji

“…MicroRNA-7 (miR-7)has been characterized as an anti-oncogenic microRNA (miRNA) in several cancers, including hepatocellular carcinoma (HCC). However, the…”
Get full text

Enhanced cancer stem cell properties of a mitotically quiescent subpopulation of p75NTR-positive cells in esophageal squamous cell carcinoma by Kojima, Hirofumi, Okumura, Tomoyuki, Yamaguchi, Tetsuji, Miwa, Takeshi, Shimada, Yutaka, Nagata, Takuya

“…Mitotically quiescent cancer stem cells (CSCs) possess higher malignant potential than other CSCs, indicating their higher contribution to therapeutic…”
Get full text

Interleukin-16 promotes cardiac fibrosis and myocardial stiffening in heart failure with preserved ejection fraction by Tamaki, Shunsuke, Mano, Toshiaki, Sakata, Yasushi, Ohtani, Tomohito, Takeda, Yasuharu, Kamimura, Daisuke, Omori, Yosuke, Tsukamoto, Yasumasa, Ikeya, Yukitoshi, Kawai, Mari, Kumanogoh, Atsushi, Hagihara, Keisuke, Ishii, Ryohei, Higashimori, Mitsuru, Kaneko, Makoto, Hasuwa, Hidetoshi, Miwa, Takeshi, Yamamoto, Kazuhiro, Komuro, Issei

“…Chronic heart failure (CHF) with preserved left ventricular (LV) ejection fraction (HFpEF) is observed in half of all patients with CHF and carries the same…”
Get full text

Clip-guided local duodenectomy for safe and minimal local resection of nonampullary duodenal neoplasms by Miwa, Takeshi, Yamada, Suguru, Shibuya, Kazuto, Hirano, Katsuhisa, Takami, Hideki, Watanabe, Toru, Hayashi, Masamichi, Yoshioka, Isaku, Kodera, Yasuhiro, Fujii, Tsutomu

“…Abstract Background Local duodenectomy and primary closure is a simple option for some nonampullary duodenal neoplasms. Minimizing the resection area while…”
Get full text

A case of squamous cell carcinoma of the breast achieved a pathological complete response after dose-dense AC + dose-dense PTX by Araki, Misato, Matsui, Koshi, Takagi, Kohji, Kanaya, Emi, Sekine, Shinichi, Nagasawa, Shiho, Watanabe, Toru, Miwa, Takeshi, Hirano, Katsuhisa, Igarashi, Takamichi, Tanaka, Haruyoshi, Shibuya, Kazuto, Hashimoto, Isaya, Hojo, Shozo, Yoshioka, Isaku, Okumura, Tomoyuki, Hirabayashi, Kenichi, Fujii, Tsutomu

“…Background Squamous cell carcinoma (SCC) of the breast is a rare form of breast cancer, accounting for approximately 0.1% of all breast cancers. It is known…”
Get full text

A novel heart failure mice model of hypertensive heart disease by angiotensin II infusion, nephrectomy, and salt loading by Tsukamoto, Yasumasa, Mano, Toshiaki, Sakata, Yasushi, Ohtani, Tomohito, Takeda, Yasuharu, Tamaki, Shunsuke, Omori, Yosuke, Ikeya, Yukitoshi, Saito, Yuki, Ishii, Ryohei, Higashimori, Mitsuru, Kaneko, Makoto, Miwa, Takeshi, Yamamoto, Kazuhiro, Komuro, Issei

“…Although the mouse heart failure (HF) model of hypertensive heart disease (HHD) is useful to investigate the pathophysiology and new therapeutic targets for…”
Get more information

Elevated cardiac tissue level of aldosterone and mineralocorticoid receptor in diastolic heart failure: Beneficial effects of mineralocorticoid receptor blocker by Ohtani, Tomohito, Ohta, Miho, Yamamoto, Kazuhiro, Mano, Toshiaki, Sakata, Yasushi, Nishio, Mayu, Takeda, Yasuharu, Yoshida, Junichi, Miwa, Takeshi, Okamoto, Mitsuhiro, Masuyama, Tohru, Nonaka, Yasuki, Hori, Masatsugu

“…Cardiac aldosterone levels have not been evaluated in diastolic heart failure (DHF), and its roles in this type of heart failure remain unclear. This study…”
Get more information

Endoscopic thyroidectomy using the EZ-VANS method by Nagata, Takuya, Shimada, Yutaka, Miwa, Takeshi, Hashimoto, Isaya, Kojima, Hirofumi, Okumura, Tomoyuki, Tsukada, Kazuhiro

“…Purpose Several video-assisted and robotic surgery techniques have been reported for resection of the thyroid and parathyroid glands. Our institute has started…”
Get full text

Repair using the pectoralis major musculocutaneous flap for refractory anastomotic leakage after total esophagectomy by Oga, Yoko, Okumura, Tomoyuki, Miwa, Takeshi, Numata, Yoshihisa, Matsumoto, Shigeki, Kaneda, Koji, Kimura, Nana, Fukasawa, Mina, Nagamori, Masakazu, Mori, Kosuke, Takeda, Naoya, Yagi, Kenta, Ito, Miki, Nagaoka, Yasuhiro, Takeshita, Chitaru, Watanabe, Toru, Hirano, Katsuhisa, Igarashi, Takamichi, Tanaka, Haruyoshi, Hashimoto, Isaya, Shibuya, Kazuto, Hojo, Shozo, Yoshioka, Isaku, Abe, Hideharu, Satake, Toshihiko, Fujii, Tsutomu

“…Background The pectoralis major musculocutaneous flap (PMMF) is a pedicled flap often used as a reconstruction option in head and neck surgery, especially in…”
Get full text

Cardiac steroidogenesis and glucocorticoid in the development of cardiac hypertrophy during the progression to heart failure by Ohtani, Tomohito, Mano, Toshiaki, Hikoso, Shungo, Sakata, Yasushi, Nishio, Mayu, Takeda, Yasuharu, Otsu, Kinya, Miwa, Takeshi, Masuyama, Tohru, Hori, Masatsugu, Yamamoto, Kazuhiro

“…BACKGROUNDElevated plasma glucocorticoid level is an independent predictor of increased mortality risk in chronic heart failure, but local biosynthesis and…”
Get full text

AT1 Receptor Blocker Added to ACE Inhibitor Provides Benefits at Advanced Stage of Hypertensive Diastolic Heart Failure by Yoshida, Junichi, Yamamoto, Kazuhiro, Mano, Toshiaki, Sakata, Yasushi, Nishikawa, Nagahiro, Nishio, Mayu, Ohtani, Tomohito, Miwa, Takeshi, Hori, Masatsugu, Masuyama, Tohru

“…ABSTRACT—Diastolic heart failure (DHF) has become a social burden; however, evidences leading to its therapeutic strategy are lacking. This study investigated…”
Get full text

Beneficial effects of bisoprolol on the survival of hypertensive diastolic heart failure model rats by Nishio, Mayu, Sakata, Yasushi, Mano, Toshiaki, Ohtani, Tomohito, Takeda, Yasuharu, Miwa, Takeshi, Hori, Masatsugu, Masuyama, Tohru, Kondo, Takashi, Yamamoto, Kazuhiro

“…Background: β-blocker therapy is an established therapeutic strategy for systolic heart failure. However, its benefits in diastolic heart failure (DHF) are…”
Get full text

Smooth muscle-specific dystrophin expression improves aberrant vasoregulation in mdx mice by ITO, Kaori, KIMURA, Shigemi, MIWA, Takeshi, DICKSON, George, THOMAS, Gail D, MIIKE, Teruhisa, OZASA, Shiro, MATSUKURA, Makoto, IKEZAWA, Makoto, YOSHIOKA, Kowashi, UENO, Hiroe, SUZUKI, Misao, ARAKI, Kimi, YAMAMURA, Ken-Ichi

“…Duchenne muscular dystrophy (DMD) is a fatal X-linked muscle-wasting disease caused by mutations of the gene encoding the cytoskeletal protein dystrophin…”
Get full text

Molecular Cloning of Frizzled-10, a Novel Member of the Frizzled Gene Family by Koike, Jun, Takagi, Atsushi, Miwa, Takeshi, Hirai, Momoki, Terada, Masaaki, Katoh, Masaru

“…The Frizzled genes encode WNT receptors. Frizzled-10 (FZD10), a novel member of the Frizzled gene family, has been cloned and characterized. Nucleotide…”
Get full text

High Prevalence of Irritable Bowel Syndrome in Medical Outpatients in Japan by Shinozaki, Masae, Fukudo, Shin, Hongo, Michio, Shimosegawa, Tooru, Sasaki, Daisuke, Matsueda, Kei, Harasawa, Shigeru, Miura, Soichiro, Mine, Tetsuya, Kaneko, Hiroshi, Arakawa, Tetsuo, Haruma, Ken, Torii, Akira, Azuma, Takeshi, Miwa, Hiroto, Fukunaga, Mikihiko, Handa, Masanori, Kitamori, Shigeru, Miwa, Takeshi

“…BACKGROUND AND GOALSThe prevalence of irritable bowel syndrome (IBS) among Japanese patients who visit hospitals departments of internal medicine is thought to…”
Get full text

Therapeutic effects of angiotensin II type 1 receptor blocker at an advanced stage of hypertensive diastolic heart failure by Nishio, Mayu, Sakata, Yasushi, Mano, Toshiaki, Yoshida, Junichi, Ohtani, Tomohito, Takeda, Yasuharu, Miwa, Takeshi, Masuyama, Tohru, Yamamoto, Kazuhiro, Hori, Masatsugu

“…OBJECTIVEAngiotensin II type 1 receptor blocker (ARB) is increasingly prescribed for the treatment of systolic heart failure with a growing body of clinical…”
Get full text

Glucocorticoids Induce Cardiac Fibrosis via Mineralocorticoid Receptor in Oxidative Stress : Contribution of Elongation Factor Eleven-Nineteen Lysine-Rich Leukemia (ELL) by Omori, Yosuke, Mano, Toshiaki, Ohtani, Tomohito, Sakata, Yasushi, Takeda, Yasuharu, Tamaki, Shunsuke, Tsukamoto, Yasumasa, Miwa, Takeshi, Yamamoto, Kazuhiro, Komuro, Issei

“…[ABSTRACT] [Background] Cardiac fibrosis is considered to be a crucial factor in the development of heart failure. Blockade of the mineralocorticoid receptor…”
Get full text

Ace inhibitor and angiotensin II type 1 receptor blocker differently regulate ventricular fibrosis in hypertensive diastolic heart failure by YAMAMOTO, Kazuhiro, MANO, Toshiaki, YOSHIDA, Junichi, SAKATA, Yasushi, NISHIKAWA, Nagahiro, NISHIO, Mayu, OHTANI, Tomohito, HORI, Masatsugu, MIWA, Takeshi, MASUYAMA, Tohru

“…Promoted myocardial stiffening has a crucial role in the transition to overt diastolic heart failure (DHF) in hypertensive hearts and is attributed to…”
Get full text

Angiotensin II type 2 receptor overexpression activates the vascular kinin system and causes vasodilation by Tsutsumi, Yoshiaki, Matsubara, Hiroaki, Masaki, Hiroya, Kurihara, Hiroki, Murasawa, Satoshi, Takai, Shinji, Miyazaki, Mizuo, Nozawa, Yoshihisa, Ozono, Ryoji, Nakagawa, Keigo, Miwa, Takeshi, Kawada, Noritaka, Mori, Yasukiyo, Shibasaki, Yasunobu, Tanaka, Yohko, Fujiyama, Soichiro, Koyama, Yohko, Fujiyama, Atsuko, Takahashi, Hakuo, Iwasaka, Toshiji

Get full text