Search Results - "Miura‐Yura, Emiri"
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Secreted factors from cultured dental pulp stem cells promoted neurite outgrowth of dorsal root ganglion neurons and ameliorated neural functions in streptozotocin‐induced diabetic mice
Published in Journal of diabetes investigation (01-01-2020)“…Aims/Introduction Transplantation of stem cells promotes axonal regeneration and angiogenesis in a paracrine manner. In the present study, we examined whether…”
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2
Simplified electrophysiological approach combining a point‐of‐care nerve conduction device and an electrocardiogram produces an accurate diagnosis of diabetic polyneuropathy
Published in Journal of diabetes investigation (01-06-2024)“…Aims/Introduction This study aimed to investigate the diagnostic potential of two simplified tests, a point‐of‐care nerve conduction device (DPNCheck™) and a…”
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3
Clinical parameters correlated with the psoas muscle index in Japanese individuals with type 2 diabetes mellitus
Published in Diabetology international (01-01-2023)“…Aims Muscle atrophy is a diabetic complication, which results in a deterioration in glycemic control in type 2 diabetes mellitus (T2DM) individuals. The psoas…”
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4
Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality
Published in Science (American Association for the Advancement of Science) (15-07-2022)“…Hematopoietic mosaic loss of Y chromosome (mLOY) is associated with increased risk of mortality and age-related diseases in men, but the causal and mechanistic…”
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Dipeptidyl Peptidase (DPP)-4 Inhibitors and Pituitary Adenylate Cyclase-Activating Polypeptide, a DPP-4 Substrate, Extend Neurite Outgrowth of Mouse Dorsal Root Ganglia Neurons: A Promising Approach in Diabetic Polyneuropathy Treatment
Published in International journal of molecular sciences (15-08-2024)“…Individuals suffering from diabetic polyneuropathy (DPN) experience debilitating symptoms such as pain, paranesthesia, and sensory disturbances, prompting a…”
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Thermal gradient ring reveals thermosensory changes in diabetic peripheral neuropathy in mice
Published in Scientific reports (13-06-2022)“…Diabetic peripheral neuropathy (DPN) includes symptoms of thermosensory impairment, which are reported to involve changes in the expression or function, or…”
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564-P: Secreted Factors from Dental Pulp Stem Cells Ameliorated Neural Functions in Streptozotocin-Induced Diabetic Mice
Published in Diabetes (New York, N.Y.) (01-06-2019)“…Aims/Introduction: We previously reported that stem cell transplantation into limb skeletal muscle improved diabetic polyneuropathy (DPN) in diabetic animal…”
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Glucagon-Like Peptide-1 Receptor Agonist Protects Dorsal Root Ganglion Neurons against Oxidative Insult
Published in Journal of diabetes research (01-01-2019)“…Objective. Diabetic polyneuropathy (DPN) is one of the most prevalent diabetic complications. We previously demonstrated that exendin-4 (Ex4), a glucagon-like…”
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The efficacy of switching basal–bolus insulin therapy to basal insulin-supported oral therapy with a glinide and an α-glucosidase inhibitor in patients with type 2 diabetes depends on insulin secretory capacity, but not on blood glucose profiles and insulin dosages prior to the switching
Published in Diabetology international (01-01-2024)“…Aims We aimed to identify patients who would benefit from basal insulin-supported oral therapy (BOT) with a glinide and an α-glucosidase inhibitor (a…”
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10
Kir6.2-deficient mice develop somatosensory dysfunction and axonal loss in the peripheral nerves
Published in iScience (21-01-2022)“…Glucose-responsive ATP-sensitive potassium channels (KATP) are expressed in a variety of tissues including nervous systems. The depolarization of the membrane…”
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11
Secreted Factors from Stem Cells of Human Exfoliated Deciduous Teeth Directly Activate Endothelial Cells to Promote All Processes of Angiogenesis
Published in Cells (Basel, Switzerland) (31-10-2020)“…Diabetes is a major risk factor for atherosclerosis and ischemic vascular diseases. Recently, regenerative medicine is expected to be a novel therapy for…”
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12
Protocol to image and analyze the morphology of mouse peripheral nerves using transmission electron microscopy
Published in STAR protocols (16-09-2022)“…Morphological analysis of peripheral nerves in mouse models can be used to characterize the pathophysiology of peripheral nerve disease, but obtaining…”
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13
Ranirestat Improved Nerve Conduction Velocities, Sensory Perception, and Intraepidermal Nerve Fiber Density in Rats with Overt Diabetic Polyneuropathy
Published in Journal of diabetes research (2019)“…Distal sensory-motor polyneuropathy is one of the most frequent diabetic complications. However, few therapies address the etiology of neurodegeneration in the…”
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Abstract 12653: The Therapy-related Clonal Hematopoiesis Driver Gene Ppm1d Promotes Inflammation and Non-ischemic Heart Failure in a Murine Model
Published in Circulation (New York, N.Y.) (17-11-2020)“…BackgroundTherapy-related clonal hematopoiesis in cancer patients is typically associated with somatic mutations in hematopoietic cell genes that encode…”
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15
Versican maintains the homeostasis of adipose tissues and regulates energy metabolism
Published in Biochemical and biophysical research communications (01-10-2024)“…Versican is a large chondroitin sulfate proteoglycan in the extracellular matrix. It plays a pivotal role in the formation of the provisional matrix. S100a4,…”
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The Cancer Therapy-Related Clonal Hematopoiesis Driver Gene Ppm1d Promotes Inflammation and Non-Ischemic Heart Failure in Mice
Published in Circulation research (03-09-2021)“…[Figure: see text]…”
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Murine models of clonal haematopoiesis to assess mechanisms of cardiovascular disease
Published in Cardiovascular research (06-05-2022)“…Abstract Clonal haematopoiesis (CH) is a phenomenon whereby somatic mutations confer a fitness advantage to haematopoietic stem and progenitor cells (HSPCs)…”
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624-P: Effects of Semaglutide Treatment on Dietary Behavior in Japanese Patients with Type 2 Diabetes Mellitus
Published in Diabetes (New York, N.Y.) (01-06-2022)“…Objective and Methods: Eating behavior questionnaire issued by the Japan Society for the Study of Obesity was administered to 41 patients who received…”
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Abstract 009: Age-related Clonal Hematopoiesis Predisposes To Hypertension In Mice Through An Inflammasome Mechanism
Published in Hypertension (Dallas, Tex. 1979) (01-09-2023)“…Abstract only Hypertension incidence increases with age and represents one of the most prevalent risk factors for cardiovascular disease (CVD). Clonal events…”
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Experimental TET2 Clonal Hematopoiesis Predisposes to Renal Hypertension Through an Inflammasome-Mediated Mechanism
Published in Circulation research (11-10-2024)“…Hypertension incidence increases with age and represents one of the most prevalent risk factors for cardiovascular disease. Clonal events in the hematopoietic…”
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