Search Results - "Miura, Naoyuki"

FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature by Sabine, Amélie, Bovay, Esther, Demir, Cansaran Saygili, Kimura, Wataru, Jaquet, Muriel, Agalarov, Yan, Zangger, Nadine, Scallan, Joshua P, Graber, Werner, Gulpinar, Elgin, Kwak, Brenda R, Mäkinen, Taija, Martinez-Corral, Inés, Ortega, Sagrario, Delorenzi, Mauro, Kiefer, Friedemann, Davis, Michael J, Djonov, Valentin, Miura, Naoyuki, Petrova, Tatiana V

“…Biomechanical forces, such as fluid shear stress, govern multiple aspects of endothelial cell biology. In blood vessels, disturbed flow is associated with…”
Get full text

Atypical cadherin FAT4 orchestrates lymphatic endothelial cell polarity in response to flow by Betterman, Kelly L, Sutton, Drew L, Secker, Genevieve A, Kazenwadel, Jan, Oszmiana, Anna, Lim, Lillian, Miura, Naoyuki, Sorokin, Lydia, Hogan, Benjamin M, Kahn, Mark L, McNeill, Helen, Harvey, Natasha L

“…The atypical cadherin FAT4 has established roles in the regulation of planar cell polarity and Hippo pathway signaling that are cell context dependent. The…”
Get full text

GATA2 is required for lymphatic vessel valve development and maintenance by Kazenwadel, Jan, Betterman, Kelly L, Chong, Chan-Eng, Stokes, Philippa H, Lee, Young K, Secker, Genevieve A, Agalarov, Yan, Demir, Cansaran Saygili, Lawrence, David M, Sutton, Drew L, Tabruyn, Sebastien P, Miura, Naoyuki, Salminen, Marjo, Petrova, Tatiana V, Matthews, Jacqueline M, Hahn, Christopher N, Scott, Hamish S, Harvey, Natasha L

“…Heterozygous germline mutations in the zinc finger transcription factor GATA2 have recently been shown to underlie a range of clinical phenotypes, including…”
Get full text

Integrin-α9 Is Required for Fibronectin Matrix Assembly during Lymphatic Valve Morphogenesis by Bazigou, Eleni, Xie, Sherry, Chen, Chun, Weston, Anne, Miura, Naoyuki, Sorokin, Lydia, Adams, Ralf, Muro, Andrés F., Sheppard, Dean, Makinen, Taija

“…Dysfunction of lymphatic valves underlies human lymphedema, yet the process of valve morphogenesis is poorly understood. Here, we show that during…”
Get full text

Mechanotransduction, PROX1, and FOXC2 Cooperate to Control Connexin37 and Calcineurin during Lymphatic-Valve Formation by Sabine, Amélie, Agalarov, Yan, Maby-El Hajjami, Hélène, Jaquet, Muriel, Hägerling, René, Pollmann, Cathrin, Bebber, Damien, Pfenniger, Anna, Miura, Naoyuki, Dormond, Olivier, Calmes, Jean-Marie, Adams, Ralf H., Mäkinen, Taija, Kiefer, Friedemann, Kwak, Brenda R., Petrova, Tatiana V.

“…Lymphatic valves are essential for efficient lymphatic transport, but the mechanisms of early lymphatic-valve morphogenesis and the role of biomechanical…”
Get full text

Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers by Mani, Sendurai A, Yang, Jing, Brooks, Mary, Schwaninger, Gunda, Zhou, Alicia, Miura, Naoyuki, Kutok, Jeffery L, Hartwell, Kimberly, Richardson, Andrea L, Weinberg, Robert A

“…The metastatic spread of epithelial cancer cells from the primary tumor to distant organs mimics the cell migrations that occur during embryogenesis. Using…”
Get full text

FOXC2 Expression Links Epithelial―Mesenchymal Transition and Stem Cell Properties in Breast Cancer by HOLLIER, Brett G, TINNIRELLO, Agata A, HERSCHKOWITZ, Jason I, GUERRA, Rudy, CHANG, Jeffrey T, MIURA, Naoyuki, ROSEN, Jeffrey M, MANI, Sendurai A, WERDEN, Steven J, EVANS, Kurt W, TAUBE, Joseph H, SARKAR, Tapasree Roy, SPHYRIS, Nathalie, SHARIATI, Maryam, KUMAR, Sreedevi V, BATTULA, Venkata L

“…Resistance to chemotherapy and metastases are the major causes of breast cancer-related mortality. Moreover, cancer stem cells (CSC) play critical roles in…”
Get full text

Foxf1 and Foxf2 control murine gut development by limiting mesenchymal Wnt signaling and promoting extracellular matrix production by Ormestad, Mattias, Astorga, Jeanette, Landgren, Henrik, Wang, Tao, Johansson, Bengt R, Miura, Naoyuki, Carlsson, Peter

“…Development of the vertebrate gut is controlled by paracrine crosstalk between the endodermal epithelium and the associated splanchnic mesoderm. In the adult,…”
Get full text

Control of retinoid levels by CYP26B1 is important for lymphatic vascular development in the mouse embryo by Bowles, Josephine, Secker, Genevieve, Nguyen, Christelle, Kazenwadel, Jan, Truong, Vy, Frampton, Emmanuelle, Curtis, Cameron, Skoczylas, Renae, Davidson, Tara-Lynn, Miura, Naoyuki, Hong, Young-Kwon, Koopman, Peter, Harvey, Natasha L., François, Mathias

“…During embryogenesis, lymphatic endothelial progenitor cells first arise from a subset of blood vascular endothelial cells in the dorsolateral aspects of the…”
Get full text

Effects of Hydroxy Groups in the A-Ring on the Anti-proteasome Activity of Flavone by Nakamura, Kasumi, Yang, Jia-Hua, Sato, Eiji, Miura, Naoyuki, Wu, Yi-Xin

“…The ubiquitin–proteasome pathway plays an important role in regulating apoptosis and the cell cycle. Recently, proteasome inhibitors have been shown to have…”
Get full text

Phosphorylation Regulates FOXC2-Mediated Transcription in Lymphatic Endothelial Cells by Ivanov, Konstantin I., Agalarov, Yan, Valmu, Leena, Samuilova, Olga, Liebl, Johanna, Houhou, Nawal, Maby-El Hajjami, Hélène, Norrmén, Camilla, Jaquet, Muriel, Miura, Naoyuki, Zangger, Nadine, Ylä-Herttuala, Seppo, Delorenzi, Mauro, Petrova, Tatiana V.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
Get full text

The regulation of endogenous retinoic acid level through CYP26B1 is required for elevation of palatal shelves by Okano, Junko, Kimura, Wataru, Papaionnou, Virginia E., Miura, Naoyuki, Yamada, Gen, Shiota, Kohei, Sakai, Yasuo

“…Background: In previous studies, we investigated the effects of excess retinoic acid (RA) during palatogenesis by RA administration to pregnant mice. In the…”
Get full text

Fecal Cyclooxygenase 2 Plus Matrix Metalloproteinase 7 mRNA Assays as a Marker for Colorectal Cancer Screening by TAKAI, Tetsunari, KANAOKA, Shigeru, YOSHIDA, Ken-Ichi, HAMAYA, Yasushi, IKUMA, Mutsuhiro, MIURA, Naoyuki, SUGIMURA, Haruhiko, KAJIMURA, Masayoshi, HISHIDA, Akira

“…We previously reported that fecal cyclooxygenase 2 (COX-2) mRNA assay, detecting COX-2 mRNA in feces, is useful for identifying subjects with colorectal cancer…”
Get full text

Copper-induced apical trafficking of ATP7B in polarized hepatoma cells provides a mechanism for biliary copper excretion by Roelofsen, Han, Wolters, Henk, Van Luyn, Marja J.A., Miura, Naoyuki, Kuipers, Folkert, Vonk, Roel J.

“…Background & Aims: Mutations in the ATP7B gene, encoding a copper-transporting P-type adenosine triphosphatase, lead to excessive hepatic copper accumulation…”
Get full text

Screening of natural medicines that efficiently activate neurite outgrowth in PC12 cells in C2C12-cultured medium by Uezato, Tadayoshi, Sato, Eiji, Miura, Naoyuki

“…We have studied the effects of natural medicines on neurite outgrowth in PC12D cells in a cultured medium of C2C12 cells. Derived from mouse myoblasts, the…”
Get full text

Identification of targets of Prox1 during in vitro vascular differentiation from embryonic stem cells: functional roles of HoxD8 in lymphangiogenesis by Harada, Kaori, Yamazaki, Tomoko, Iwata, Caname, Yoshimatsu, Yasuhiro, Sase, Hitoshi, Mishima, Koichi, Morishita, Yasuyuki, Hirashima, Masanori, Oike, Yuichi, Suda, Toshio, Miura, Naoyuki, Watabe, Tetsuro, Miyazono, Kohei

“…During lymphatic development, Prox1 plays central roles in the differentiation of blood vascular endothelial cells (BECs) into lymphatic endothelial cells…”
Get full text

Potential usefulness of detecting cyclooxygenase 2 messenger RNA in feces for colorectal cancer screening by Kanaoka, Shigeru, Yoshida, Ken-Ichi, Miura, Naoyuki, Sugimura, Haruhiko, Kajimura, Masayoshi

“…Cyclooxygenase 2 (COX-2) is overexpressed frequently in aerodigestive tumors, especially in colorectal tumors. Therefore, it may be a suitable biomarker for…”
Get full text

Foxc2 in pharyngeal arch mesenchyme is important for aortic arch artery remodelling and ventricular septum formation by UDDIN, Mohammad Khaja Mafij, KIMURA, Wataru, ISHIKURA, Tomoyuki, KOSEKI, Haruhiko, YOSHIDA, Nobuaki, ISLAM, Mohammad Johirul, AMIN, Mohammed Badrul, NAKAMURA, Kasumi, WU, Yi-Xin, SATO, Eiji, AOTO, Kazushi, MIURA, Naoyuki

“…The forkhead box C2 (Foxc2) protein is a member of the forkhead/winged helix transcription factor family and plays an essential role in cardiovascular…”
Get full text

Liver tumor formation by a mutant retinoblastoma protein in the transgenic mice is caused by an upregulation of c-Myc target genes by Wang, Bo, Hikosaka, Keisuke, Sultana, Nishat, Sharkar, Mohammad Tofael Kabir, Noritake, Hidenao, Kimura, Wataru, Wu, Yi-Xin, Kobayashi, Yoshimasa, Uezato, Tadayoshi, Miura, Naoyuki

“…► Fifty percent of the mutant Rb transgenic mice produced liver tumors. ► In the tumor, Foxm1, Skp2, Bmi1 and AP-1 mRNAs were up-regulated. ► No increase in…”
Get full text

Data supporting the regulation of FOXC2 in podocyte dysfunction by Datta, Neeta, Lindfors, Sonja, Miura, Naoyuki, Saleem, Moin A., Lehtonen, Sanna

“…This data article shows the expression levels of specific podocyte injury markers and podocyte slit diaphragm protein nephrin in obese and lean Zucker rat…”
Get full text