Search Results - "Mittler, U"

Targeted therapeutics in treatment of children and young adults with solid tumors: an expert survey and review of the literature by Grunewald, T G P, Greulich, N, Kontny, U, Frühwald, M, Rutkowski, S, Kordes, U, Scheurlen, W, Schmidt, W, Stachel, D, Metzler, M, Mittler, U, Graf, N, Benesch, M, Burdach, S

“…Although prognosis of children with solid tumors is steadily improving, long-term survival is not achievable in all patients, especially in patients with…”
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Familial urticaria pigmentosa associated with thrombocytosis as the initial symptom of systemic mastocytosis and Down's syndrome by Jappe, U, Aumann, V, Mittler, U, Gollnick, H

“…ABSTRACT Most cases of urticaria pigmentosa are confined to the skin, but visceral involvement and/or haematological abnormalities have been observed. It is…”
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CTGF (IGFBP-rP2) is specifically expressed in malignant lymphoblasts of patients with acute lymphoblastic leukaemia (ALL) by VORWERK, P, WEX, H, HOHMANN, B, OH, Y, ROSENFELD, R. G, MITTLER, U

“…Connective tissue growth factor (CTGF) is a major chemotactic and mitogenic factor for connective tissue cells. The amino acid sequence shares an overall…”
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Expression of components of the IGF signalling system in childhood acute lymphoblastic leukaemia by Vorwerk, P, Wex, H, Hohmann, B, Mohnike, K, Schmidt, U, Mittler, U

“…Background: Alterations in the insulin-like growth factor (IGF) system have been reported for different tumours. They are of particular interest in the search…”
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Elevated serum levels of IGFBP-2 found in children suffering from acute leukaemia is accompanied by the occurrence of IGFBP-2 mRNA in the tumour clone by WEX, H, VORWERK, P, MOHNIKE, K, BRETSCHNEIDER, D, KLUBA, U, AUMANN, V, BLUM, W. F, MITTLER, U

“…Insulin-like growth factor-binding proteins (IGFBPs) are important modulators of IGF action. In 50 children suffering from acute lymphoblastic leukaemia (ALL),…”
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Genetic Instability in Osteoblastic Tumors of the Skeletal System by Radig, K., Schneider-Stock, R., Mittler, U., Neumann, H.W., Roessner, A.

“…At the histological level, the differential diagnosis of osteoblastic bone tumors is characterized by several problems that cannot be solved by coventional…”
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Final height and puberty in 40 patients after antileukaemic treatment during childhood by MOHNIKE, K, DÖRFFEL, W, TIMME, J, KLUBA, U, AUMANN, V, VORWERK, P, MITTLER, U

“…Endocrine dysfunction and damage of the epiphysial growth plates have been reported as late effects of antileukaemic treatment during childhood. It is a common…”
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Expression of MDR1/p-glycoprotein and multidrug resistance-associated protein in childhood solid tumours by ODA, Y, RÖSE, I, RADIG, K, WAGEMANN, W, MITTLER, U, ROESSNER, A

“…We evaluated the expression of MDR1/p-glycoprotein in paediatric tumours using reverse transcriptase polymerase chain reaction (RT-PCR), RNA dot blot analysis,…”
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Absence of hepatitis after treatment with a pasteurized factor VIII concentrate in patients with hemophilia and no previous transfusions by Schimpf, K, Mannucci, P M, Kreutz, W, Brackmann, H H, Auerswald, G, Ciavarella, N, Mösseler, J, DeRosa, V, Kraus, B, Brueckmann, C

“…Post-transfusion hepatitis is frequent among patients with hemophilia who are treated with concentrated factor VIII prepared from pooled plasma, especially if…”
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von Willebrand Factor–Cleaving Protease in Thrombotic Thrombocytopenic Purpura and the Hemolytic–Uremic Syndrome by Furlan, Miha, Robles, Rodolfo, Galbusera, Miriam, Remuzzi, Giuseppe, Kyrle, Paul A, Brenner, Brigitte, Krause, Manuela, Scharrer, Inge, Aumann, Volker, Mittler, Uwe, Solenthaler, Max, Lämmle, Bernhard

“…Thrombotic thrombocytopenic purpura, a disseminated thrombotic microangiopathy, was initially described by Moschcowitz in 1924. 1 Three decades later, Gasser…”
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Factor VII deficiency: clinical manifestation of 717 subjects from Europe and Latin America with mutations in the factor 7 gene by HERRMANN, F. H., WULFF, K., AUERSWALD, G., SCHULMAN, S., ASTERMARK, J., BATOROVA, A., KREUZ, W., POLLMANN, H., RUIZ-SAEZ, A., DE BOSCH, N., SALAZAR-SANCHEZ, L.

“…The congenital FVII deficiency (FVIID) is a rare haemorrhagic disorder with an autosomal recessive pattern of inheritance. Data on phenotype and the genotype…”
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Postoperative neoadjuvant chemotherapy before radiotherapy as compared to immediate radiotherapy followed by maintenance chemotherapy in the treatment of medulloblastoma in childhood: results of the German prospective randomized trial HIT '91 by Kortmann, R D, Kühl, J, Timmermann, B, Mittler, U, Urban, C, Budach, V, Richter, E, Willich, N, Flentje, M, Berthold, F, Slavc, I, Wolff, J, Meisner, C, Wiestler, O, Sörensen, N, Warmuth-Metz, M, Bamberg, M

“…The German Society of Pediatric Hematology and Oncology (GPOH) conducted a randomized, prospective, multicenter trial (HIT '91) in order to improve the…”
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Expression of P-glycoprotein in high grade osteosarcomas with special emphasis on chondroblastic subtype by Radig, K, Häckel, C, Herting, J, Oda, Y, Mittler, U, Neumann, W, Roessner, A

“…The development of chemoresistance is one of the major clinical problems in the therapy of malignant bone tumors in childhood. The expression of membrane-bound…”
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Alterations of p53 gene in soft tissue and bone tumors by Roessner, A, Schneider-Stock, R, Radig, K, Neumann, W, Mittler, U

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Pigmentierter neuroektodermaler Tumor des Kindesalters by KLAEREN, R, AUMANN, V, RADIG, K, GERLACH, K. L, MITTLER, U

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Insulin-Like Growth Factor Binding Protein-2 at Diagnosis of Childhood Acute Lymphoblastic Leukemia and the Prediction of Relapse Risk by Vorwerk, Peter, Mohnike, Klaus, Wex, Heike, Röhl, Friedrich-Wilhelm, Zimmermann, Martin, Blum, Werner F., Mittler, Uwe

“…Despite remarkable advances in the clinical outcome of most children with acute lymphoblastic leukemia, a substantial number of patients ultimately relapse or…”
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Near‐total splenectomy for hereditary spherocytosis: clinical prospects in relation to disease severity by Stoehr, Gerhard A., Sobh, Julian N., Luecken, Jan, Heidemann, Kathrin, Mittler, Uwe, Hilgers, Reinhard, Eber, Stefan W.

“…Summary We prospectively studied the efficacy of near total splenectomy (NTS) for managing hereditary spherocytosis (HS) based on haemoglobin (Hb), total…”
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Familial clustering of Langerhans cell histiocytosis by Aricò, Maurizio, Nichols, Kim, Whitlock, James A., Arceci, Robert, Haupt, Riccardo, Mittler, Uwe, Kühne, Thomas, Lombardi, Alessandra, Ishii, Eiichi, Egeler, R. Maarten, Danesino, Cesare

“…Langerhans cell histiocytosis (LCH) is considered a non‐hereditary disorder. Evaluation of the few familial cases might provide insight into its aetiology and…”
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Desmoid tumors of the head and neck by Motsch, C, Schmitt, J, Roessner, A, Mittler, U, Freigang, B

“…Desmoid tumors of the head and neck, also known as aggressive fibromatoses, are rare. They are soft tissue neoplasms arising from musculoaponeurotic structures…”
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Prospective study on the influence of radiochemotherapy on pituitary function in children with acute leukaemia and NHL by Kluba, U, Mittler, U, Mohnike, K, Aumann, V, Kröning, G, Kapitza, W, Röppnack, R

“…To assess effects of chemo- and radiotherapy on the endocrine system 31 children with acute leukaemia and NHL (3 AML, 24 ALL, 4 NHL) were investigated…”
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