Search Results - "Mitterreiter, Stefan"

Identification of candidate substrates for ectodomain shedding by the metalloprotease-disintegrin ADAM8 by Naus, Silvia, Reipschläger, Simone, Wildeboer, Dirk, Lichtenthaler, Stefan F, Mitterreiter, Stefan, Guan, Ziqiang, Moss, Marcia L, Bartsch, Jörg W

“…ADAM proteases are type I transmembrane proteins with extracellular metalloprotease domains. As for most ADAM family members, ADAM8 (CD156a, MS2) is involved…”
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Identification of ADAM proteinase substrates in neurodegeneration and neuroinflammation by Naus, Silvia, Reipschläger, Simone, Wildeboer, Dirk, MInai, Yuji, Lichtenthaler, Stefan F, Mitterreiter, Stefan, Guan, Ziqiang, Moss, Marcia L, Bartsch, Jörg W

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Niemann–Pick type C cells show cholesterol dependent decrease of APP expression at the cell surface and its increased processing through the β-secretase pathway by Malnar, Martina, Kosicek, Marko, Mitterreiter, Stefan, Omerbasic, Damir, Lichtenthaler, Stefan F., Goate, Alison, Hecimovic, Silva

“…The link between cholesterol and Alzheimer's disease has recently been revealed in Niemann–Pick type C disease. We found that NPC1 − /− cells show decreased…”
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Bepridil and amiodarone simultaneously target the Alzheimer's disease beta- and gamma-secretase via distinct mechanisms by Mitterreiter, Stefan, Page, Richard M, Kamp, Frits, Hopson, Jessika, Winkler, Edith, Ha, Huy-Riem, Hamid, Runa, Herms, Jochen, Mayer, Thomas U, Nelson, Deborah J, Steiner, Harald, Stahl, Tobias, Zeitschel, Ulrike, Rossner, Steffen, Haass, Christian, Lichtenthaler, Stefan F

“…The two proteases beta-secretase and gamma-secretase generate the amyloid beta peptide and are drug targets for Alzheimer's disease. Here we tested the…”
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O1-04-01: Novel drugs simultaneously modulate both beta- and gamma-secretase cleavage of the amyloid precursor protein by Lichtenthaler, Stefan F, Mitterreiter, Stefan, Haass, Christian

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