Search Results - "Mitsuru Nishiyama"

Animal Models of Cushing's Syndrome by Nishiyama, Mitsuru, Iwasaki, Yasumasa, Makino, Shinya

“…Abstract Endogenous Cushing's syndrome is characterized by unique clinical features and comorbidities, and progress in the analysis of its genetic pathogenesis…”
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Update in Pathogenesis, Diagnosis, and Therapy of Prolactinoma by Fukuhara, Noriaki, Nishiyama, Mitsuru, Iwasaki, Yasumasa

“…Prolactinomas comprise 30–50% of all pituitary neuroendocrine tumors, frequently occur in females aged 20 to 50, and cause hypogonadism and infertility. In…”
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Biological roles of growth hormone/prolactin from an evolutionary perspective by Iwasaki, Yasumasa, Nishiyama, Mitsuru, Corcoran, Dylan, Araki, Takako

“…Although growth hormone (GH) and prolactin (PRL) are usually recognized as pituitary hormones, their expression is not restricted to the adenohypophysis and…”
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Hypopituitarism due to CNS Aspergillus Infection by Funakoshi, Shogo, Nishiyama, Mitsuru, Komori, Masahiro, Hyodo, Masamitsu, Kawanishi, Yu, Ueba, Tetsuya, Fujimoto, Shimpei, Terada, Yoshio

“…A 59-year-old man was admitted to our hospital with hyponatremia. An endocrine examination indicated panhypopituitarism, and magnetic resonance imaging…”
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Immunohistochemistry for aldosterone synthase CYP11B2 and matrix-assisted laser desorption ionization imaging mass spectrometry for in-situ aldosterone detection by Zhang, Zhen, Sugiura, Yuki, Mune, Tomoatsu, Nishiyama, Mitsuru, Terada, Yoshio, Mukai, Kuniaki, Nishimoto, Koshiro

“…PURPOSE OF REVIEWImmunohistochemistry for aldosterone synthase (CYP11B2) has markedly provided a comprehensive picture of the adrenocortical diseases,…”
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Unilateral adrenalectomy partially improved hyperglycemia in a patient with primary bilateral macronodular adrenal hyperplasia by Nishiyama, Mitsuru, Karashima, Takashi, Iwasaki, Yasumasa, Terada, Yoshio, Fujimoto, Shimpei

“…Primary bilateral macronodular adrenal hyperplasia (PBMAH) is characterized by bilateral multiple adrenal macro-nodules that often cause mild over-secretion of…”
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Adult-onset Langerhans cell histiocytosis changing CNS lesion from pituitary to suprasellar extension by Kadowaki, Yuji, Nishiyama, Mitsuru, Nakamura, Makoto, Morisaka, Hiroyuki, Fujimoto, Shimpei, Terada, Yoshio, Kojima, Kensuke

“…Summary Langerhans cell histiocytosis (LCH) is a rare disease characterized by the proliferation of abnormal Langerhans cells in various tissues and organs,…”
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PPARβ/δ regulates the human SIRT1 gene transcription via Sp1 by Okazaki, Mizuho, Iwasaki, Yasumasa, Nishiyama, Mitsuru, Taguchi, Takafumi, Tsugita, Makoto, Nakayama, Shuichi, Kambayashi, Machiko, Hashimoto, Kozo, Terada, Yoshio

“…NAD-dependent deacetylase SIRT1 is known to be activated by caloric restriction and is related to longevity. A natural polyphenolic compound resveratrol is…”
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Regulation of Glucocorticoid Receptor Transcription and Nuclear Translocation during Single and Repeated Immobilization Stress by Noguchi, Tohru, Makino, Shinya, Matsumoto, Reiko, Nakayama, Shuichi, Nishiyama, Mitsuru, Terada, Yoshio, Hashimoto, Kozo

“…We have previously reported reduced glucocorticoid receptor (GR) mRNA levels in the hippocampus and hypothalamic paraventricular nucleus (PVN) during repeated…”
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Hormonal Regulation of Acetyl-CoA Carboxylase Isoenzyme Gene Transcription by ZHAO, Li Feng, IWASAKI, Yasumasa, ZHE, Wang, NISHIYAMA, Mitsuru, TAGUCHI, Takafumi, TSUGITA, Makoto, KAMBAYASHI, Machiko, HASHIMOTO, Kozo, TERADA, Yoshio

“…Both glucocorticoid and insulin are known to have an anabolic effect on lipogenesis. Acetyl-CoA, an intermediate product of glycolysis, is supplied for fatty…”
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GABA Release from Proopiomelanocortin Neurons by Hentges, Shane T, Nishiyama, Mitsuru, Overstreet, Linda S, Stenzel-Poore, Mary, Williams, John T, Low, Malcolm J

“…Neural networks controlling food intake and energy homeostasis clearly involve proopiomelanocortin (POMC) neurons and their peptide transmitters…”
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Is the metabolic syndrome an intracellular Cushing state? Effects of multiple humoral factors on the transcriptional activity of the hepatic glucocorticoid-activating enzyme (11β-hydroxysteroid dehydrogenase type 1) gene by Iwasaki, Yasumasa, Takayasu, Shinobu, Nishiyama, Mitsuru, Tsugita, Makoto, Taguchi, Takafumi, Asai, Masato, Yoshida, Masanori, Kambayashi, Machiko, Hashimoto, Kozo

“…Although glucocorticoid, as “gluco-” literally implies, plays an important role in maintaining the blood glucose level, excess of glucocorticoid…”
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Predominant role of 25OHD in the negative regulation of PTH expression: Clinical relevance for hypovitaminosis D by Kawahara, Masayuki, Iwasaki, Yasumasa, Sakaguchi, Kazushige, Taguchi, Takafumi, Nishiyama, Mitsuru, Nigawara, Takeshi, Tsugita, Makoto, Kambayashi, Machiko, Suda, Toshihoro, Hashimoto, Kozo

“…Although severe deficiency of bioactive vitamin D (1,25OH2D) causes rickets, mild insufficiency of the hormone, known as hypovitaminosis D, is responsible for…”
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Insulin exhibits short-term anti-inflammatory but long-term proinflammatory effects in vitro by Iwasaki, Yasumasa, Nishiyama, Mitsuru, Taguchi, Takafumi, Asai, Masato, Yoshida, Masanori, Kambayashi, Machiko, Terada, Yoshio, Hashimoto, Kozo

“…Although insulin is indispensable for maintaining glucose homeostasis, it is still controversial whether or not a high concentration of insulin is deleterious…”
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Remarkable Cystic Expansion of Microprolactinoma Causing Diabetes Insipidus during Pregnancy by Amano, Eri, Nishiyama, Mitsuru, Iwasaki, Yasumasa, Matsushima, Sachio, Oguri, Hiroyoshi, Fukuhara, Noriaki, Nishioka, Hiroshi, Yamada, Shozo, Inoshita, Naoko, Fukaya, Takao, Terada, Yoshio

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Lipopolysaccharide Stimulates Proopiomelanocortin Gene Expression in AtT20 Corticotroph Cells by IWASAKI, Yasumasa, TAGUCHI, Takafumi, NISHIYAMA, Mitsuru, ASAI, Masato, YOSHIDA, Masanori, KAMBAYASHI, Machiko, TAKAO, Toshihiro, HASHIMOTO, Kozo

“…While lipopolysaccharides (LPS) are known to activate the hypothalamo-pituitary-adrenal axis, their direct effects on proopiomelanocortin (POMC) and…”
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Corticotropin-releasing hormone (CRH) transgenic mice display hyperphagia with increased Agouti-related protein mRNA in the hypothalamic arcuate nucleus by Nakayama, Shuichi, Nishiyama, Mitsuru, Iwasaki, Yasumasa, Shinahara, Masayuki, Okada, Yasushi, Tsuda, Masayuki, Okazaki, Mizuho, Tsugita, Makoto, Taguchi, Takafumi, Makino, Shinya, Stenzel-Poore, Mary P, Hashimoto, Kozo, Terada, Yoshio

“…Although glucocorticoid-induced hyperphagia is observed in the patients with glucocorticoid treatment or Cushing’s syndrome, its molecular mechanism is not…”
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Hormonal Regulation of Glycolytic Enzyme Gene and Pyruvate Dehydrogenase Kinase/Phosphatase Gene Transcription by WANG, Zhe, IWASAKI, Yasumasa, ZHAO, Li Feng, NISHIYAMA, Mitsuru, TAGUCHI, Takafumi, TSUGITA, Makoto, KAMBAYASHI, Machiko, HASHIMOTO, Kozo, TERADA, Yoshio

“…Both glucocorticoid and insulin are known to have an anabolic effect on lipogenesis. The glycolytic pathway is a part of the lipogenic pathway in the liver,…”
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Pituitary Tumors: Molecular Insights, Diagnosis, and Targeted Therapy by Kageyama, Kazunori, Nishiyama, Mitsuru

“…The anterior pituitary gland comprises a heterogeneous population of pituitary cells [...]…”
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Plasma Adiponectin Levels are Increased Despite Insulin Resistance in Corticotropin-releasing Hormone Transgenic Mice, an Animal Model of Cushing Syndrome by SHINAHARA, Masayuki, NISHIYAMA, Mitsuru, IWASAKI, Yasumasa, NAKAYAMA, Shuichi, NOGUCHI, Toru, KAMBAYASHI, Machiko, OKADA, Yasushi, TSUDA, Masayuki, STENZEL-POORE, Mary P., HASHIMOTO, Kozo, TERADA, Yoshio

“…Adiponectin (AdN), an adipokine derived from the adipose tissue, has an insulin-sensitizing effect, and plasma AdN is shown to be decreased in obesity and/or…”
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