Search Results - "Mitsumoto, Tatsuya"

Lack of hepatocarcinogenicity of 2,2’-[1,2-ethanediylbis(oxymethylene)]bis-oxirane, 3-hydroxy-2-naphthoic acid, and acetoacetanilide in a medium-term rat liver bioassay by Yamagata, Hiroshi, Saito, Tsubasa, Okamoto, Takezo, Satomoto, Kensuke, Mitsumoto, Tatsuya, Wakita, Atsushi, Nakamura, Maki, Hayashi, Takahiro, Kuroiwa, Yuichi

“…The carcinogenicity of 2,2’-[1,2-ethanediylbis(oxymethylene)]bis-oxirane (ethylene glycol diglycidyl ether; EGDE), 3-hydroxy-2-naphthoic acid (HNA), and…”
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The effect of aging on the repeated-dose liver micronucleus assay using diethylnitrosamine by Satomoto, Kensuke, Suzuki, Isamu, Mita, Koji, Wakita, Atsushi, Yamagata, Hiroshi, Mitsumoto, Tatsuya, Hamada, Shuichi

“…The repeated-dose liver micronucleus (RDLMN) assay has been well-developed and applied because of its simplicity and the ease of integration into general…”
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Detection of hepatocarcinogens by combination of liver micronucleus assay and histopathological examination in 2-week or 4-week repeated dose studies by Hamada, Shuichi, Shigano, Miyuki, Wako, Yumi, Kawasako, Kazufumi, Satomoto, Kensuke, Mitsumoto, Tatsuya, Fukuda, Takayuki, Ohyama, Wakako, Morita, Takeshi, Hayashi, Makoto

“…Currently, revisions to the ICH S1 guidance on rodent carcinogenicity testing are being proposed. Application of this approach would reduce the use of animals…”
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A simple table lookup method for PET/CT partial volume correction using a point-spread function in diagnosing lymph node metastasis by Sakaguchi, Yuichi, Mizoguchi, Noriko, Mitsumoto, Tatsuya, Mitsumoto, Katsuhiko, Himuro, Kazuhiko, Ohya, Nobuyoshi, Kaneko, Koichiro, Baba, Shingo, Abe, Koichiro, Onizuka, Yoshihiko, Sasaki, Masayuki

“…Objective We evaluated the partial volume effect in PET/CT images and developed a simple correction method to address this problem. Methods Six spheres and the…”
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Introduction of the New Product: PET/CT [Discovery IQ by Mitsumoto, Tatsuya

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Diagnostic performance of Tc-99m HMPAO SPECT for early and late onset Alzheimer’s disease: a clinical evaluation of linearization correction by Mitsumoto, Tatsuya, Ohya, Nobuyoshi, Ichimiya, Atsushi, Sakaguchi, Yuichi, Kiyota, Aya, Abe, Koichiro, Morishita, Junji, Sasaki, Masayuki

“…Objective This study examined the influence of linearization correction (LC) on brain perfusion single-photon emission computed tomography (SPECT) for the…”
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Formation of hepatocyte cytoplasmic inclusions and their contribution to methylcarbamate-induced hepatocarcinogenesis in F344 rats by Takimoto, Norifumi, Ishii, Yuji, Mitsumoto, Tatsuya, Takasu, Shinji, Namiki, Moeka, Shibutani, Makoto, Ogawa, Kumiko

“…Abstract Methylcarbamate (MC), a reaction product between dimethyl dicarbonate and ammonia or ammonium ion, is a potent hepatocarcinogen in F344 rats. Various…”
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Comprehensive analysis of the general toxicity, genotoxicity, and carcinogenicity of 3-acetyl-2,5-dimethylfuran in male gpt delta rats by Takasu, Shinji, Ishii, Yuji, Namiki, Moeka, Nakamura, Kenji, Mitsumoto, Tatsuya, Takimoto, Norifumi, Nohmi, Takehiko, Ogawa, Kumiko

“…The safety of flavoring agents has been evaluated according to classification by chemical structure and using a decision tree approach. The genotoxic potential…”
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Visualization of the distribution of anthraquinone components from madder roots in rat kidneys by desorption electrospray ionization-time-of-flight mass spectrometry imaging by Ishii, Yuji, Nakamura, Kenji, Mitsumoto, Tatsuya, Takimoto, Norifumi, Namiki, Moeka, Takasu, Shinji, Ogawa, Kumiko

“…Madder color (MC), a natural dye isolated from Rubia tinctorum, is a potent carcinogen that targets the outer stripe of outer medulla (OSOM) in the kidneys of…”
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Intraocular Melanoma in a Crl:CD(SD) Rat by OGAWA, Tatsuya, MITSUMOTO, Tatsuya, OZAWA, Naoyuki, KOMATSU, Masahiko, YAHATA, Megumi, EDAMOTO, Hiroshi, NISHIMURA, Nobuo, OKAZAKI, Shuzo

“…Corneal dermoid and squamous epithelial tumors arising from the cornea, sclera and eyelids are known ocular tumors in rats. However, tumors arising from the…”
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Hepatocyte proliferation activity in untreated rats, measured by immunohistochemical detection of Ki-67: The effect of age on the repeated-dose liver micronucleus assay by Satomoto, Kensuke, Aoki, Moeko, Wakita, Atsushi, Yamagata, Hiroshi, Mitsumoto, Tatsuya, Okamoto, Takezo, Harada, Ryoko, Hamada, Shuichi

“…The repeated-dose liver micronucleus (RDLMN) assay is a widely accepted method for detecting genotoxic substances. We investigated the effect of animal age on…”
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Site-specific genotoxicity of rubiadin: localization and histopathological changes in the kidneys of rats by Mitsumoto, Tatsuya, Ishii, Yuji, Takimoto, Norifumi, Takasu, Shinji, Namiki, Moeka, Nohmi, Takehiko, Umemura, Takashi, Ogawa, Kumiko

“…Rubiadin (Rub) is a genotoxic component of madder color (MC) that is extracted from the root of Rubia tinctorum L. MC induces renal tumors and preneoplastic…”
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Phantom study on three-dimensional target volume delineation by PET/CT-based auto-contouring by Zhang, Tiejiao, Tachiya, Yosuke, Sakaguchi, Yuichi, Mitsumoto, Katsuhiko, Mitsumoto, Tatsuya, Ohya, Nobuyoshi, Sasaki, Masayuki

“…The aim of this study was to determine an appropriate threshold value for delineation of the target volume in PET/CT and to investigate whether we could…”
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A 90-day subchronic toxicity study of Myrrh in F344 rats by Mitsumoto, Tatsuya, Ishii, Yuji, Namiki, Moeka, Nakamura, Kenji, Takasu, Shinji, Ogawa, Kumiko

“…Myrrh is a flavoring agent and food additive. Here, we performed a subchronic toxicity study of Myrrh in male and female F344 rats by feeding at 5,000, 15,000…”
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The effect of aging on the repeated-dose liver micronucleus assay using diethylnitrosamine by Kensuke Satomoto, Isamu Suzuki, Koji Mita, Atsushi Wakita, Hiroshi Yamagata, Tatsuya Mitsumoto, Shuichi Hamada

“…[Abstract] Background: The repeated-dose liver micronucleus (RDLMN) assay has been well-developed and applied because of its simplicity and the ease of…”
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Lack of hepatocarcinogenicity of 2,2'-[1,2-ethanediylbis(oxymethylene)]bis-oxirane, 3-hydroxy-2-naphthoic acid, and acetoacetanilide in a medium-term rat liver bioassay by YAMAGATA, Hiroshi, SAITO, Tsubasa, OKAMOTO, Takezo, SATOMOTO, Kensuke, MITSUMOTO, Tatsuya, WAKITA, Atsushi, NAKAMUR, Maki, HAYASHI, Takahiro, KUROIWA, Yuichi

“…The carcinogenicity of 2,2'-[1,2-ethanediylbis(oxymethylene)]bis-oxirane (ethylene glycol diglycidyl ether; EGDE), 3-hydroxy-2-naphthoic acid (HNA), and…”
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Detection of hepatocarcinogens by combination of liver micronucleus assay and histopathological examination in 2-week or 4-week repeated dose studies by Shuichi Hamada, Miyuki Shigano, Yumi Wako, Kazufumi Kawasako, Kensuke Satomoto, Tatsuya Mitsumoto, Takayuki Fukuda, Wakako Ohyama, Takeshi Morita, Makoto Hayashi

“…[Abstract] Background: Currently, revisions to the ICH S1 guidance on rodent carcinogenicity testing are being proposed. Application of this approach would…”
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Crl:CD(SD)ラットにみられた眼球内黒色腫の1例 by 小川, 竜也, 満元, 達也, 小澤, 直幸, 小松, 真彦, 八幡, めぐみ, 枝元, 洋, 西村, 信雄, 岡崎, 修三

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