Search Results - "Mitrović, Marina"
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Human estrogen receptor α antagonists, part 2: Synthesis driven by rational design, in vitro antiproliferative, and in vivo anticancer evaluation of innovative coumarin-related antiestrogens as breast cancer suppressants
Published in European journal of medicinal chemistry (05-01-2022)“…New twelve in silico designed coumarin-based ERα antagonists, namely 3DQ-1a to 3DQ-1е, were synthesized and confirmed as selective ERα antagonists, showing…”
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Human Estrogen Receptor α Antagonists. Part 1: 3‑D QSAR-Driven Rational Design of Innovative Coumarin-Related Antiestrogens as Breast Cancer Suppressants through Structure-Based and Ligand-Based Studies
Published in Journal of chemical information and modeling (25-10-2021)“…The estrogen receptor α (ERα) represents a 17β-estradiol-inducible transcriptional regulator that initiates the RNA polymerase II-dependent transcriptional…”
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Four newly synthesized enones induce mitochondrial-mediated apoptosis and G2/M cell cycle arrest in colorectal and cervical cancer cells
Published in RSC advances (23-10-2024)“…Over the last few decades, we have gained insight into how researchers attempted to modify some natural molecules to be utilized as prospective agents for…”
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Insights into Molecular Mechanisms of Anticancer Activity of Juniperus communis Essential Oil in HeLa and HCT 116 Cells
Published in Plants (Basel) (23-08-2024)“…As cancer remains a significant global health challenge, there is an increasing need for novel therapeutic approaches. We investigated the antitumor potential…”
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ANTITUMOR EFFECTS OF VANILLIN BASED CHALCONE ANALOGUES IN VITRO
Published in Acta Poloniae pharmaceutica (01-01-2020)Get full text
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Activity of superoxide dismutase and catalase and content of malondialdehyde in seminal plasma of infertile patients
Published in Medicinski pregled (01-09-2010)“…The reactive oxygen species, the highly reactive metabolites of oxygen, play a crucial role in both the normal function and the metabolism of sperm cells…”
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Impact of aromaticity on anticancer activity of polypyridyl ruthenium(II) complexes: synthesis, structure, DNA/protein binding, lipophilicity and anticancer activity
Published in Journal of biological inorganic chemistry (01-10-2017)“…With the aim of assessing how the aromaticity of the inert chelating ligand can influence the activity of ruthenium(II) polypyridyl complexes, two new…”
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Search for new biologically active compounds: in vitro studies of antitumor and antimicrobial activity of dirhodium(II,II) paddlewheel complexes
Published in Dalton transactions : an international journal of inorganic chemistry (04-06-2024)“…Four neutral Rh1-Rh4 complexes of the general formula [Rh (CH COO) L ], where L is an -alkylimidazole ligand, were synthesized and characterized using various…”
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Effect of β-cyclodextrin encapsulation on cytotoxic activity of acetylshikonin against HCT-116 and MDA-MB-231 cancer cell lines
Published in Saudi pharmaceutical journal (01-01-2020)“…Acetylshikonin (AcSh), as a red colored pigment found in roots of the plants from family Boraginaceae, showed excellent cytotoxic activity. Due to its…”
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Diagnostic agreement of presepsin, procalcitonin, C-reactive protein and white blood cell count in patients with suspected sepsis
Published in Acta Facultatis Medicae Naissensis (2024)“…Introduction/Aim. Agreement or disagreement of inflammatory parameters becomes important for making diagnosis when disparate values are encountered in a…”
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Antitumor effect of mifepristone on human endometrial stromal cell line
Published in Vojnosanitetski pregled (2021)“…Background/Aim. The main cause for development of endometrial hyperplasia is unopposed effect of estrogen on endometrial cells. The aim of our study was to…”
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Teucrium polium induces apoptosis in peripheral blood lymphocytes isolated from human chronic lymphocytic leukemia
Published in Vojnosanitetski pregled (01-01-2020)“…Background/Aim. Chronic lymhocytic leukemia (CLL) is considered more as a disease of cells accumulation due to the defect in apoptosis rather than deregulated…”
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Chrysin induces apoptosis in peripheral blood lymphocytes isolated from human chronic lymphocytic leukemia
Published in Anti-cancer agents in medicinal chemistry (01-01-2015)“…Chronic lymphocytic leukemia (CLL) develops due to an imbalance between apoptosis and proliferation of B lymphocytes. Chrysin induced apoptosis in leukemia…”
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Induction of mitochondrial apoptotic pathway by raloxifene and estrogen in human endometrial stromal ThESC cell line
Published in Archives of medical science (01-03-2017)“…Endometrial hyperplasia is a condition that occurs as a result of hormonal imbalance between estrogen and progesterone. Morphological disturbance of…”
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Cytotoxic and apoptotic effect of chalcone 5 on mouse colon cancer cells CT-26
Published in Indian journal of biochemistry & biophysics (01-03-2024)Get full text
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METHOTREXATE AND MYOTREXATE INDUCE APOPTOSIS IN HUMAN MYOMA FIBROBLASTS (T hES CELL LINE) VIA MITOCHONDRIAL PATHWAY
Published in Acta Poloniae pharmaceutica (01-05-2015)“…Uterine leiomyomas (fibroids) are the most common benign tumors in women of reproductive age. Although the local application of low doses of methotrexate (MTX)…”
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SOME CHARACTERISTIC OF BIOLOGICAL AND CHEMICAL CONTAMINATION OF SOIL IN THE AREA OF CANTON SARAJEVO
Published in Cereal research communications (01-01-2009)“…Soil is an important natural resource which along with water, air and organisms forms an ecosystem. Under the influence of multiple pedogenesis factors and…”
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Expression of estrogen and progesterone receptors in subcutaneous endometriosis
Published in Archives of biological sciences (2010)“…Endometriosis is a clinical disorder defined by the presence of functional endometrial tissue outside the uterine cavity. Depending on the localization of the…”
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Protective role of IL-33/ST2 axis in Con A-induced hepatitis
Published in Journal of hepatology (01-01-2012)“…Background & Aims We used Concanavalin A-induced liver injury to study the role of Interleukin 33 and its receptor ST2 in the induction of inflammatory…”
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Cytokine profile in chronic hepatitis C: An observation
Published in Cytokine (Philadelphia, Pa.) (01-08-2017)“…•Cytokine levels in patients group were heterogeneous, spread in wide range of values.•Grouping data according to disease-relevant factors showed high…”
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