Search Results - "Mitroka, James G."
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Utility of imaging mass spectrometry (IMS) by matrix-assisted laser desorption ionization (MALDI) on an ion trap mass spectrometer in the analysis of drugs and metabolites in biological tissues
Published in Journal of pharmacological and toxicological methods (01-05-2007)“…The properties and potential liabilities of drug candidate are investigated in detailed ADME assays and in toxicity studies, where findings are placed in…”
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A multiyear comparison of flipped- vs. lecture-based teaching on student success in a pharmaceutical science class
Published in Currents in pharmacy teaching and learning (01-01-2020)“…To gauge the potential effect of mode of content delivery on overall student success in a pharmaceutical sciences course in a doctor of pharmacy program…”
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AMIDE N-GLUCURONIDATION OF MAXIPOST CATALYZED BY UDP-GLUCURONOSYLTRANSFERASE 2B7 IN HUMANS
Published in Drug metabolism and disposition (01-05-2004)“…MaxiPost [(3 S )-(+)-(5-chloro-2-methoxyphenyl)-1,3-dihydro-3-fluoro-6-(trifluoromethyl)-2 H -indole-2-one), or BMS-204352)] is a potent and specific maxi-K…”
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Defining Reality: The Potential Role of Pharmacists in Assessing the Impact of Progesterone Receptor Modulators and Misoprostol in Reproductive Health
Published in The Annals of pharmacotherapy (01-01-2011)“…Medical abortion is increasingly heralded as an ideal method for decreasing maternal mortality in health-care resource-deprived areas and as an answer to the…”
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Analysis of low level radioactive metabolites in biological fluids using high-performance liquid chromatography with microplate scintillation counting: Method validation and application
Published in Journal of pharmaceutical and biomedical analysis (01-09-2005)“…TopCount, a microplate scintillation counter (MSC), has been recently employed as an off-line liquid radiochromatographic detector for radioactive metabolite…”
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Oral Bioavailability and Disposition of [14C]Omapatrilat in Healthy Subjects
Published in Journal of clinical pharmacology (01-08-2001)“…The objective of this study was to determine the absolute oral bioavailability and disposition of omapatrilat. This singledose, randomized, crossover study of…”
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Disposition of Radiolabeled Ifetroban in Rats, Dogs, Monkeys, and Humans
Published in Drug metabolism and disposition (01-08-2000)“…Ifetroban is a potent and selective thromboxane receptor antagonist. This study was conducted to characterize the pharmacokinetics, absolute bioavailability,…”
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BMS-180448, a novel glyburide-reversible cardioprotective agent, enhances postischemic recovery of contractile function in dogs
Published in The Journal of pharmacology and experimental therapeutics (01-02-1996)“…BMS-180448 has been found to retain the cardioprotective potency of its chemically related analog, cromakalim, although having significantly less peripheral…”
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Cerebrospinal fluid retrieval in the conscious dog: a methods development study
Published in Journal of investigative surgery (01-01-1995)“…A chronic cerebrospinal fluid access system is described for use in the conscious sling-restrained dog. In a pilot study of ten dogs, a fenestrated…”
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