Search Results - "Mitragotri, S."

Modeling skin permeability to hydrophilic and hydrophobic solutes based on four permeation pathways by Mitragotri, Samir

“…Barrier properties of skin originate from low permeability of stratum corneum. The objective of this paper is to compile fundamentally-based analytical…”
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Shape effect in active targeting of nanoparticles to inflamed cerebral endothelium under static and flow conditions by Da Silva-Candal, A., Brown, T., Krishnan, V., Lopez-Loureiro, I., Ávila-Gómez, P., Pusuluri, A., Pérez-Díaz, A., Correa-Paz, C., Hervella, P., Castillo, J., Mitragotri, S., Campos, F.

“…Endothelial cells represent the first biological barrier for compounds, including nanoparticles, administered via the intravascular route. In the case of…”
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Engineering approaches to transdermal drug delivery: a tribute to contributions of prof. Robert Langer by Mitragotri, S

“…Transdermal drug delivery continues to provide an advantageous route of drug administration over injections. While the number of drugs delivered by passive…”
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Current status and future potential of transdermal drug delivery by Mitragotri, Samir, Langer, Robert, Prausnitz, Mark R

“…The past twenty five years have seen an explosion in the creation and discovery of new medicinal agents. Related innovations in drug delivery systems have not…”
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Synergistic effect of enhancers for transdermal drug delivery by MITRAGOTRI, Samir

“…Transdermal drug delivery offers a non-invasive route of drug administration, although its applications are limited by low skin permeability. Various enhancers…”
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Delivery systems for intradermal vaccination by Kim, Y C, Jarrahian, C, Zehrung, D, Mitragotri, S, Prausnitz, M R

“…Intradermal (ID) vaccination can offer improved immunity and simpler logistics of delivery, but its use in medicine is limited by the need for simple, reliable…”
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Ultrasound‐mediated delivery of flexibility‐tunable polymer drug conjugates for treating glioblastoma by Sun, Tao, Krishnan, Vinu, Pan, Daniel C., Filippov, Sergey K., Ravid, Sagi, Sarode, Apoorva, Kim, Jayoung, Zhang, Yongzhi, Power, Chanikarn, Aday, Sezin, Guo, Junling, Karp, Jeffrey M., McDannold, Nathan J., Mitragotri, Samir S.

“…Effective chemotherapy delivery for glioblastoma multiforme (GBM) is limited by drug transport across the blood–brain barrier and poor efficacy of single…”
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Data Mining in Indian Equity Markets: building low Risk, Market beating Portfolios by Mitragotri, S. R., Patel, N.

“…Over the last five decades, business academics have identified over 300 determinants that potentially influence stock returns. However, we still do not know…”
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Induction of cancer-specific cytotoxicity towards human prostate and skin cells using quercetin and ultrasound by PALIWAL, S, SUNDARAM, J, MITRAGOTRI, S

“…Bioflavonoids, such as quercetin, have recently emerged as a new class of chemotherapeutic drugs for the treatment of various cancer types, but are marred by…”
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Transdermal delivery of heparin and low-molecular weight heparin using low-frequency ultrasound by MITRAGOTRI, Samir, KOST, Joseph

“…PURPOSE. Heparin and low-molecular weight heparin (LMWH) are the most commonly used anticoagulants and are administered by intravenous or subcutaneous…”
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Frequency dependence of sonophoresis by TEZEL, Ahmet, SENS, Ashley, TUCHSCHERER, Joe, MITRAGOTRI, Samir

“…Application of low-frequency ultrasound has been shown to increase skin permeability, thereby facilitating delivery of macromolecules (low-frequency…”
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Dependence of low-frequency sonophoresis on ultrasound parameters; distance of the horn and intensity by Terahara, T, Mitragotri, S, Kost, J, Langer, R

“…Sonophoresis at a frequency of 20 kHz has been shown to enhance transdermal drug delivery, a phenomenon referred to as low-frequency sonophoresis. This study…”
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Low-Frequency Sonophoresis: A Noninvasive Method of Drug Delivery and Diagnostics by Mitragotri, Samir, Kost, Joseph

“…Transdermal drug delivery offers an attractive alternative to injections and oral medications. However, applications of transdermal drug delivery are limited…”
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Evaluation of chemical enhancers in the transdermal delivery of lidocaine by Lee, Philip J., Ahmad, Naina, Langer, Robert, Mitragotri, Samir, Prasad Shastri, V.

“…The effect of various classes of chemical enhancers was investigated for the transdermal delivery of the anesthetic lidocaine across pig and human skin in…”
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In situ determination of partition and diffusion coefficients in the lipid bilayers of stratum corneum by MITRAGOTRI, Samir

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Immunization without needles by Mitragotri, Samir

“…Most current immunization procedures make use of needles and syringes for vaccine administration. With the increase in the number of immunizations that…”
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Challenges associated with penetration of nanoparticles across cell and tissue barriers: A review of current status and future prospects by Barua, Sutapa, Mitragotri, Samir

“…•Transport barriers for delivery of nanoparticles are discussed.•Permeation across the endothelium, diffusion in the interstitium and entry into cells is…”
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Combined effect of low-frequency ultrasound and iontophoresis : Applications for transdermal heparin delivery by LONG LE, KOST, Joseph, MITRAGOTRI, Samir

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Effect of bilayer disruption on transdermal transport of low-molecular weight hydrophobic solutes by MITRAGOTRI, Samir

“…Applications of transdermal drug delivery are limited by low skin permeability. Several chemicals have been used to enhance transdermal drug transport, many of…”
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Non-invasive delivery strategies for biologics by Anselmo, Aaron C., Gokarn, Yatin, Mitragotri, Samir

“…The requirement for delivery by injection is currently a limitation for the use of biologic drugs such as antibodies. In this Review, Mitragotri and colleagues…”
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