Search Results - "Mitra, Shiladitya"
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MMPs in learning and memory and neuropsychiatric disorders
Published in Cellular and molecular life sciences : CMLS (01-08-2019)“…Matrix metalloproteinases (MMPs) are a group of over twenty proteases, operating chiefly extracellularly to cleave components of the extracellular matrix, cell…”
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Automatically annotated motion tracking identifies a distinct social behavioral profile following chronic social defeat stress
Published in Nature communications (18-07-2023)“…Severe stress exposure increases the risk of stress-related disorders such as major depressive disorder (MDD). An essential characteristic of MDD is the…”
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Psychosocial Stress Induces Schizophrenia-Like Behavior in Mice With Reduced MMP-9 Activity
Published in Frontiers in behavioral neuroscience (29-08-2019)“…Understanding gene¬-environment interactions in the pathogenesis of schizophrenia remains a major research challenge. Matrix metalloproteinase-9 (MMP-9) has…”
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Hypothalamic protein profiling from mice subjected to social defeat stress
Published in Molecular brain (27-05-2024)“…The Hypothalmic-Pituitary-Adrenal axis also known as the HPA axis is central to stress response. It also acts as the relay center between the body and the…”
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Absence of Wdr13 Gene Predisposes Mice to Mild Social Isolation - Chronic Stress, Leading to Depression-Like Phenotype Associated With Differential Expression of Synaptic Proteins
Published in Frontiers in molecular neuroscience (25-04-2018)“…We earlier reported that the male mice lacking the gene ( ) showed mild anxiety, better memory retention, and up-regulation of synaptic proteins in the…”
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Implication of Genetic Deletion of Wdr13 in Mice: Mild Anxiety, Better Performance in Spatial Memory Task, with Upregulation of Multiple Synaptic Proteins
Published in Frontiers in molecular neuroscience (30-08-2016)“…WDR13 expresses from the X chromosome and has a highly conserved coding sequence. There have been multiple associations of WDR13 with memory. However, its…”
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Deep phenotyping reveals CRH and FKBP51-dependent behavioral profiles following chronic social stress exposure in male mice
Published in Neuropsychopharmacology (New York, N.Y.) (22-10-2024)“…The co-chaperone FKBP51, encoded by FKBP5 gene, is recognized as a psychiatric risk factor for anxiety and depressive disorders due to its crucial role in the…”
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The curious case of the spinning neuronal mass [version 1; peer review: 1 not approved]
Published in F1000 research (2015)“…Rotating cells have been reported in past. Rotation of cells and cell clusters has been associated with migration and development. This observation reports for…”
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Metabolic effects of early life stress and pre‐pregnancy obesity are long lasting and sex specific in mice
Published in The European journal of neuroscience (01-07-2023)“…Early life stress (ELS) is associated with metabolic, cognitive, and psychiatric diseases and has a very high prevalence, highlighting the urgent need for a…”
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Sex-specific and opposed effects of FKBP51 in glutamatergic and GABAergic neurons: Implications for stress susceptibility and resilience
Published in Proceedings of the National Academy of Sciences - PNAS (06-06-2023)“…Mental health disorders often arise as a combination of environmental and genetic factors. The gene, encoding the GR co-chaperone FKBP51, has been uncovered as…”
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