Search Results - "Mitomo, Katsuyuki"

Phenotypic Correction of Hemophilia A by Ectopic Expression of Activated Factor VII in Platelets by Ohmori, Tsukasa, Ishiwata, Akira, Kashiwakura, Yuji, Madoiwa, Seiji, Mitomo, Katsuyuki, Suzuki, Hidenori, Hasegawa, Mamoru, Mimuro, Jun, Sakata, Yoichi

“…Platelets are receiving much attention as novel target cells to secrete a coagulation factor for hemophilia gene therapy. In order to extend the application of…”
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Src Homology Region 2 (SH2) Domain-Containing Phosphatase-1 Dephosphorylates B Cell Linker Protein/SH2 Domain Leukocyte Protein of 65 kDa and Selectively Regulates c-Jun NH2-Terminal Kinase Activation in B Cells by Mizuno, Kazuya, Tagawa, Yuko, Mitomo, Katsuyuki, Arimura, Yutaka, Hatano, Norikazu, Katagiri, Tatsuo, Ogimoto, Mami, Yakura, Hidetaka

“…Src homology region 2 (SH2) domain-containing phosphatase-1 (SHP-1) is a cytosolic protein tyrosine phosphatase containing two SH2 domains in its NH2 terminus…”
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CD45 Is Required for CD40-induced Inhibition of DNA Synthesis and Regulation of c-Jun NH2-terminal Kinase and p38 in BAL-17 B Cells by Arimura, Yutaka, Ogimoto, Mami, Mitomo, Katsuyuki, Katagiri, Tatsuo, Yamamoto, Ken-ichi, Volarevic, Sinisa, Mizuno, Kazuya, Yakura, Hidetaka

“…Stimulation of B cell antigen receptor (BCR) may induce proliferation, differentiation, or apoptosis, depending upon the maturational stage of the cell and the…”
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Toward Gene Therapy for Cystic Fibrosis Using a Lentivirus Pseudotyped With Sendai Virus Envelopes by Mitomo, Katsuyuki, Griesenbach, Uta, Inoue, Makoto, Somerton, Lucinda, Meng, Cuixiang, Akiba, Eiji, Tabata, Toshiaki, Ueda, Yasuji, Frankel, Gad M, Farley, Raymond, Singh, Charanjit, Chan, Mario, Munkonge, Felix, Brum, Andrea, Xenariou, Stefania, Escudero-Garcia, Sara, Hasegawa, Mamoru, Alton, Eric WFW

“…Gene therapy for cystic fibrosis (CF) is making encouraging progress into clinical trials. However, further improvements in transduction efficiency are…”
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High avidity chimeric monoclonal antibodies against the extracellular domains of human aquaporin‐4 competing with the neuromyelitis optica autoantibody, NMO‐IgG by Miyazaki‐Komine, Kaori, Takai, Yoshiki, Huang, Ping, Kusano‐Arai, Osamu, Iwanari, Hiroko, Misu, Tatsuro, Koda, Katsushi, Mitomo, Katsuyuki, Sakihama, Toshiko, Toyama, Yoshiaki, Fujihara, Kazuo, Hamakubo, Takao, Yasui, Masato, Abe, Yoichiro

“…Background and Purpose Most of the cases of neuromyelitis optica (NMO) are characterized by the presence of an autoantibody, NMO‐IgG, which recognizes the…”
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Abstract 4323: Antibodies against TfR inhibit growth of tumor cells both in vitro and in vivo by Zhang, Lilin, Ukai, Yoshinori, Nomura, Fumiko, Aikawa, Youichi, Kayukawa, Yoko, Mitomo, Katsuyuki, Kouda, Katsushi, Kodaka, Romi, Kurosawa, Gene, Kurosawa, Yoshikazu, Morishita, Kazuhiro, Sudo, Yukio

“…Abstract Transferrin receptor (TfR) is a type II transmembrane glycoprotein regulating intracellular uptake of iron, and is therefore involved in cell survival…”
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Efficient expression of a transgene in platelets using simian immunodeficiency virus-based vector harboring glycoprotein Ibα promoter: in vivo model for platelet-targeting gene therapy by Ohmori, Tsukasa, Mimuro, Jun, Takano, Katsuhiro, Madoiwa, Seiji, Kashiwakura, Yuji, Ishiwata, Akira, Niimura, Masanori, Mitomo, Katsuyuki, Tabata, Toshiaki, Hasegawa, Mamoru, Ozawa, Keiya, Sakata, Yoichi

“…Platelets release several mediators that modify vascular integrity and hemostasis. In the present study, we developed a technique for efficient transgene…”
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Efficient expression of a transgene in platelets using simian immunodeficiency virus-based vector harboring glycoprotein Ibalpha promoter: in vivo model for platelet-targeting gene therapy by Ohmori, Tsukasa, Mimuro, Jun, Takano, Katsuhiro, Madoiwa, Seiji, Kashiwakura, Yuji, Ishiwata, Akira, Niimura, Masanori, Mitomo, Katsuyuki, Tabata, Toshiaki, Hasegawa, Mamoru, Ozawa, Keiya, Sakata, Yoichi

“…Platelets release several mediators that modify vascular integrity and hemostasis. In the present study, we developed a technique for efficient transgene…”
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Src Homology Region 2 Domain-Containing Phosphatase 1 Positively Regulates B Cell Receptor-Induced Apoptosis by Modulating Association of B Cell Linker Protein with Nck and Activation of c-Jun NH2-Terminal Kinase by Mizuno, Kazuya, Tagawa, Yuko, Mitomo, Katsuyuki, Watanabe, Noriyuki, Katagiri, Tatsuo, Ogimoto, Mami, Yakura, Hidetaka

“…Src homology region 2 domain-containing phosphatase 1 (SHP-1) is a key mediator in lymphocyte differentiation, proliferation, and activation. We previously…”
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Two different cellular redox systems regulate the DNA-binding activity of the p50 subunit of NF-kappa B in vitro by Mitomo, K, Nakayama, K, Fujimoto, K, Sun, X, Seki, S, Yamamoto, K

“…The NF-kappa B/Rel/Dorsal (NRD) transcription factor family binds target DNA sequences through their conserved N-terminal basic region that contains a single…”
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367. Lentivirus Pseudotyped with Envelope Proteins F and HN from Sendai Virus Transduce Airway Epithelium Efficiency and Persistently by Griesenbach, Uta, Mitomo, Katsuyuki, Inoue, Makoto, Somerton, Lucinda, Farley, Raymond, Singh, Charanjit, Tabata, Toshiaki, Ueda, Yasuji, Fujikawa, Satoshi, Washizawa, Kentaro, Hasegawa, Mamoru, Alton, Eric W.F.W.

“…We have previously shown that recombinant Sendai-virus (SeV) vector transduces airway epithelium efficiently via the apical membrane. This is in part due to…”
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Involvement of a NF-kappa B-like transcription factor in the activation of the interleukin-6 gene by inflammatory lymphokines by Shimizu, H, Mitomo, K, Watanabe, T, Okamoto, S, Yamamoto, K

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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CD45 Negatively Regulates Lyn Activity by Dephosphorylating Both Positive and Negative Regulatory Tyrosine Residues in Immature B Cells by Katagiri, Tatsuo, Ogimoto, Mami, Hasegawa, Kiminori, Arimura, Yutaka, Mitomo, Katsuyuki, Okada, Masato, Clark, Marcus R, Mizuno, Kazuya, Yakura, Hidetaka

“…Using CD45-deficient clones from the immature B cell line, WEHI-231, we previously demonstrated that CD45 selectively dephosphorylates the Src-family protein…”
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A novel 66-kilodalton protein complexes with Rrn6, Rrn7, and TATA-binding protein to promote polymerase I transcription initiation in Saccharomyces cerevisiae by Lin, Chen Wei, Moorefield, Beth, Payne, John, Aprikian, Pavel, Mitomo, Katsuyuki, Reeder, Ronald H.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Opposing regulation of B cell receptor-induced activation of mitogen-activated protein kinases by CD45 by Ogimoto, Mami, Arimura, Yutaka, Katagiri, Tatsuo, Mitomo, Katsuyuki, Woodgett, James R., Nebreda, Angel R., Mizuno, Kazuya, Yakura, Hidetaka

“…In this study, we examined the contribution made by CD45 to B cell antigen receptor (BCR)-induced activation of mitogen-activated protein kinase (MAPK) family…”
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Requirement of PEST domain tyrosine phosphatase PEP in B cell antigen receptor‐induced growth arrest and apoptosis by Hasegawa, Kiminori, Yajima, Hiroaki, Katagiri, Tatsuo, Ogimoto, Mami, Arimura, Yutaka, Mitomo, Katsuyuki, Mashima, Keisuke, Mizuno, Kazuya, Yakura, Hidetaka

“…Signaling events leading to B cell growth or apoptosis are beginning to be unravelled, but detailed information is still lacking. To identify signaling…”
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Functional and antigenic properties of complement receptor type 2, CR2 by MITOMO, K, FUJITA, T, IIDA, K

“…This is the first report demonstrating that C3d receptor (CR2) has functional activity in regulating complement cascade. Purified CR2 was examined for its…”
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A solid-phase anti-C3 assay for detection of immune complexes in six distinguished forms by Iida, K, Mitomo, K, Fujita, T, Tamura, N

“…A solid-phase anti-C3 assay detecting immune complexes associated with C3 fragments is described. Two monoclonal antibodies against C3 fragments are used; one…”
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A Lymphoid Cell-Specific Nuclear Factor Containing c-Rel-Like Proteins Preferentially Interacts with Interleukin-6 κΒ-Related Motifs Whose Activities Are Repressed in Lymphoid Cells by Nakayama, Kohzo, Shimizu, Hiroko, Mitomo, Katsuyuki, Watanabe, Tomoo, Okamoto, Shu-Ichi, Yamamoto, Ken-Ichi

“…The proto-oncoprotein c-Rel is a member of the nuclear factor κB transcription factor family, which includes the p50 and p65 subunits of nuclear factor κB. We…”
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Involvement of a NF-κB-Like Transcription Factor in the Activation of the Interleukin-6 Gene by Inflammatory Lymphokines by Shimizu, Hiroko, Mitomo, Katsuyuki, Watanabe, Tomoo, Okamoto, Shuichi, Yamamoto, Ken-Ichi

“…Interleukin-6 (IL-6) is one of the major mediators of inflammation, and its expression is inducible by the other inflammatory lymphokines, interleukin-1 (IL-1)…”
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