Search Results - "Mitnaul, L J"

The cytoplasmic tail of influenza A virus neuraminidase (NA) affects NA incorporation into virions, virion morphology, and virulence in mice but is not essential for virus replication by Mitnaul, L J, Castrucci, M R, Murti, K G, Kawaoka, Y

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Coordinate Regulation of Tetrahydrobiopterin Turnover and Phenylalanine Hydroxylase Activity in Rat Liver Cells by Mitnaul, Lyndon J., Shiman, Ross

“…This work had two purposes: (i) to determine in vivo whether liver phenylalanine hydroxylase (PAH) is regulated by its substrates phenylalanine and…”
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Balanced Hemagglutinin and Neuraminidase Activities Are Critical for Efficient Replication of Influenza A Virus by Mitnaul, L J, Matrosovich, M N, Castrucci, M R, Tuzikov, A B, Bovin, N V, Kobasa, D, Kawaoka, Y

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Miniaturization of cell-based beta-lactamase-dependent FRET assays to ultra-high throughput formats to identify agonists of human liver X receptors by Chin, Jayne, Adams, Alan D, Bouffard, Aileen, Green, Ahren, Lacson, Raul G, Smith, Todd, Fischer, Paul A, Menke, John G, Sparrow, Carl P, Mitnaul, Lyndon J

“…Activation of liver X receptors (LXRs) induces reverse cholesterol transport and increases high-density lipoprotein cholesterol in vivo. Here, we describe…”
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Rare-variant pathogenicity triage and inclusion of synonymous variants improves analysis of disease associations of orphan G protein–coupled receptors by Dershem, Ridge, Metpally, Raghu P.R., Jeffreys, Kirk, Krishnamurthy, Sarathbabu, Smelser, Diane T., Hershfinkel, Michal, Carey, David J., Robishaw, Janet D., Breitwieser, Gerda E.

“…The pace of deorphanization of G protein–coupled receptors (GPCRs) has slowed, and new approaches are required. Small molecule targeting of orphan GPCRs can…”
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Simple permeation absorber for sampling and preconcentrating hazardous air contaminants by Zaromb, S, Woo, C S, Quandt, K, Rice, L M, Fermaint, A, Mitnaul, L J

“…A permeation absorber was developed and experimentally evaluated for sampling and preconcentrating vapors of a primary aromatic amine into a small volume (ca…”
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Plasma proteomic associations with genetics and health in the UK Biobank by Sun, Benjamin B., Chiou, Joshua, Traylor, Matthew, Benner, Christian, Hsu, Yi-Hsiang, Richardson, Tom G., Surendran, Praveen, Mahajan, Anubha, Robins, Chloe, Vasquez-Grinnell, Steven G., Hou, Liping, Kvikstad, Erika M., Burren, Oliver S., Davitte, Jonathan, Ferber, Kyle L., Gillies, Christopher E., Hedman, Åsa K., Hu, Sile, Lin, Tinchi, Mikkilineni, Rajesh, Pendergrass, Rion K., Pickering, Corran, Prins, Bram, Baird, Denis, Chen, Chia-Yen, Ward, Lucas D., Deaton, Aimee M., Welsh, Samantha, Willis, Carissa M., Lehner, Nick, Arnold, Matthias, Wörheide, Maria A., Suhre, Karsten, Kastenmüller, Gabi, Sethi, Anurag, Cule, Madeleine, Raj, Anil, Burkitt-Gray, Lucy, Melamud, Eugene, Black, Mary Helen, Fauman, Eric B., Howson, Joanna M. M., Kang, Hyun Min, McCarthy, Mark I., Nioi, Paul, Petrovski, Slavé, Scott, Robert A., Smith, Erin N., Szalma, Sándor, Waterworth, Dawn M., Mitnaul, Lyndon J., Szustakowski, Joseph D., Gibson, Bradford W., Miller, Melissa R., Whelan, Christopher D.

“…The Pharma Proteomics Project is a precompetitive biopharmaceutical consortium characterizing the plasma proteomic profiles of 54,219 UK Biobank participants…”
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Different roles of liver X receptor α and β in lipid metabolism: Effects of an α-selective and a dual agonist in mice deficient in each subtype by Lund, Erik G., Peterson, Laurence B., Adams, Alan D., Lam, My-Hanh N., Burton, Charlotte A., Chin, Jayne, Guo, Qiu, Huang, Shaei, Latham, Melanie, Lopez, Jacqueline C., Menke, John G., Milot, Denise P., Mitnaul, Lyndon J., Rex-Rabe, Sandra E., Rosa, Raymond L., Tian, Jenny Y., Wright, Samuel D., Sparrow, Carl P.

“…Liver X receptor (LXR) α and LXRβ are closely related nuclear receptors that respond to elevated levels of intracellular cholesterol by enhancing transcription…”
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Increased hypercholesterolemia and atherosclerosis in mice lacking both ApoE and leptin receptor by Wu, Kenneth K., Wu, Tsuei-Ju, Chin, Jayne, Mitnaul, Lyndon J., Hernandez, Melba, Cai, Tian-Quan, Ren, Ning, Waters, M. Gerard, Wright, Samuel D., Cheng, Kang

“…Diabetes mellitus is one of the major risk factors associated with atherosclerosis and coronary heart disease but the mechanistic links between the disease and…”
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