Search Results - "Mitev, Vanio"

Insight into the Metabolite Pattern of Psoriasis: Correlation among Homocysteine, Methionine, and Polyamines by Ruseva, Silviya, Popova, Inna, Lozanov, Valentin, Mitev, Vanio

“…Psoriasis is an incurable dermatological disorder, characterized by increased epidermal cell proliferation. Numerous studies have focused on the modulation of…”
Get full text

Rare host variants in ciliary expressed genes contribute to COVID-19 severity in Bulgarian patients by Kamenarova, Kunka, Kachakova-Yordanova, Darina, Baymakova, Magdalena, Georgiev, Martin, Mihova, Kalina, Petkova, Veronika, Beltcheva, Olga, Argirova, Radka, Atanasov, Petar, Kunchev, Metodi, Andonova, Radina, Zasheva, Anelia, Drenska, Rumiana, Ivanov, Ivaylo, Pantileeva, Diana, Koleva, Vesselina, Penev, Anton, Lekova-Nikova, Diana, Georgiev, Delyan, Pencheva, Daniela, Bozhilova, Radosveta, Ivanova, Nevyana, Dimova, Ivanka, Plochev, Kamen, Popov, Georgi, Popivanov, Ivan, Gabrovsky, Nikolay, Leseva, Magdalena, Mitev, Vanio, Kaneva, Radka

“…Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) causes coronavirus disease 2019 (COVID-19), a pneumonia with extremely heterogeneous clinical…”
Get full text

Promoter hypermethylation of CDKN2A, MGMT, MLH1, and DAPK genes in laryngeal squamous cell carcinoma and their associations with clinical profiles of the patients by Pierini, Stefano, Jordanov, Stanislav H., Mitkova, Atanaska V., Chalakov, Ivan J., Melnicharov, Mincho B., Kunev, Kuncho V., Mitev, Vanio I., Kaneva, Radka P., Goranova, Teodora E.

“…Background Laryngeal squamous cell carcinoma (laryngeal SCC) is a frequently occurring cancer of the head and neck area. Epigenetic changes of tumor‐related…”
Get full text

The effect of sample size on polygenic hazard models for prostate cancer by Karunamuni, Roshan A, Huynh-Le, Minh-Phuong, Fan, Chun C, Eeles, Rosalind A, Easton, Douglas F, Kote-Jarai, ZSofia, Amin Al Olama, Ali, Benlloch Garcia, Sara, Muir, Kenneth, Gronberg, Henrik, Wiklund, Fredrik, Aly, Markus, Schleutker, Johanna, Sipeky, Csilla, Tammela, Teuvo L J, Nordestgaard, Børge G, Key, Tim J, Travis, Ruth C, Neal, David E, Donovan, Jenny L, Hamdy, Freddie C, Pharoah, Paul, Pashayan, Nora, Khaw, Kay-Tee, Thibodeau, Stephen N, McDonnell, Shannon K, Schaid, Daniel J, Maier, Christiane, Vogel, Walther, Luedeke, Manuel, Herkommer, Kathleen, Kibel, Adam S, Cybulski, Cezary, Wokolorczyk, Dominika, Kluzniak, Wojciech, Cannon-Albright, Lisa, Brenner, Hermann, Schöttker, Ben, Holleczek, Bernd, Park, Jong Y, Sellers, Thomas A, Lin, Hui-Yi, Slavov, Chavdar, Kaneva, Radka, Mitev, Vanio, Batra, Jyotsna, Clements, Judith A, Spurdle, Amanda, Teixeira, Manuel R, Paulo, Paula, Maia, Sofia, Pandha, Hardev, Michael, Agnieszka, Mills, Ian G, Andreassen, Ole A, Dale, Anders M, Seibert, Tyler M

“…We determined the effect of sample size on performance of polygenic hazard score (PHS) models in prostate cancer. Age and genotypes were obtained for 40,861…”
Get full text

Clinical and genetic variability among Bulgarian patients with autosomal recessive spastic ataxia of Charlevoix–Saguenay by Chamova, Teodora, Ivanova, Neviana, Cherninkova, Sylvia, Koleva, Maya, Zlatareva, Dora, Bojinova, Veneta, Mihova, Kalina, Georgiev, Martin, Ferdinandov, Dilyan, Bichev, Stoyan, Kaneva, Radka, Mitev, Vanio, Jordanova, Albena, Tournev, Ivailo

“…Background Autosomal recessive spastic ataxia ofCharlevoix–Saguenay (ARSACS) is a rare neurodegenerative disorder characterizedby early‐onset cerebellar…”
Get full text

A familial case of severe infantile nephronophthisis explained by oligogenic inheritance by Penchev, Valentin, Boueva, Anelia, M.D, Kamenarova, Kunka, PhD, Roussinov, Dimitar, M.D, Tzveova, Reni, PhD, Ivanova, Mariya, PhD, Dimitrova, Violeta, M.D, Kremensky, Ivo, M.D., PhD, Mitev, Vanio, M.D.,D.Sc, Kaneva, Radka, PhD, Beltcheva, Olga, PhD

“…Abstract Renal cysts are common malformation during the prenatal and postnatal period and frequent cause of chronic kidney or ESRD. More than 70 genes have…”
Get full text

Identification of a novel de novo mutation of CREBBP in a patient with Rubinstein-Taybi syndrome by targeted next-generation sequencing: a case report by Kamenarova, Kunka, PhD, Simeonov, Emil, MD, PhD, Tzveova, Reni, PhD, Dacheva, Daniela, PhD, Penkov, Marin, MD, Kremensky, Ivo, MD, PhD, Perenovska, Penka, MD, PhD, Mitev, Vanio, MD, PhD, Kaneva, Radka, PhD

“…Summary Rubinstein-Taybi syndrome (RSTS) is a rare autosomal dominant congenital disorder (prevalence, 1:125 000-720 000) characterized by broad thumbs and…”
Get full text

No evidence of association between 118A>G OPRM1 polymorphism and heroin dependence in a large Bulgarian case–control sample by Nikolov, Momchil A, Beltcheva, Olga, Galabova, Antoaneta, Ljubenova, Anna, Jankova, Elena, Gergov, Galin, Russev, Atanas A, Lynskey, Michael T, Nelson, Elliot C, Nesheva, Eleonora, Krasteva, Dorita, Lazarov, Philip, Mitev, Vanio I, Kremensky, Ivo M, Kaneva, Radka P, Todorov, Alexandre A

“…Abstract The μ-opioid receptor is the primary site of action of most opioids. The 118A>G (rs1799971) polymorphism in exon 1 of the μ-opioid receptor gene (…”
Get full text

Determination of plasma aminothiols by high performance liquid chromatography after precolumn derivatization with N-(2-acridonyl)maleimide by Benkova, Bistra, Lozanov, Valentin, Ivanov, Ivaylo P., Todorova, Antonia, Milanov, Ivan, Mitev, Vanio

“…Design, synthesis and properties of new derivatization reagent N-(2-acridonyl)-maleimide (MIAC) for thiol groups is presented. The reaction of MIAC with…”
Get full text

Transmission disequilibrium of DISC1 haplotypes in Bulgarian families with affective disorder by Ivanova, Mina Angelova, Kremensky, Ivo M, Christova, Tanya N, Kostov, Christian S, Milanova, Vihra K, Mitev, Vanio I, Kaneva, Radka P

Get full text

CK2 Is Acting Upstream of MEK3/6 as a Part of the Signal Control of ERK1/2 and p38 MAPK during Keratinocytes Autocrine Differentiation by Isaeva, Antonia R., Mitev, Vanio I.

“…Protein kinase CK2 (formerly termed “casein kinase II”) is a ubiquitously in mammalian cells distributed Ser/Thr kinase, with global role in cell regulation…”
Get full text

Investigation of candidate genes reveals significant statistical epistasis between DISC1 and TPH2 in Bulgarian affective disorder patients by Ivanova-Stoevska, Mina, Penchev, Mladen, Stoyanova, Vessela, Vladimirova, Rossitza, Milanova, Vihra, Kremensky, Ivo, Mitev, Vanio, Kaneva, Radka

“…The aim of the present study was to search for joint influence of variants in affective disorder (AD) candidate genes by investigating statistical epistasis…”
Get full text

Liquid chromatography method for simultaneous analysis of amino acids and biogenic amines in biological fluids with simultaneous gradient of pH and acetonitrile by Lozanov, Valentin, Benkova, Bistra, Mateva, Lyudmila, Petrov, Stefan, Popov, Elenko, Slavov, Chavdar, Mitev, Vanio

“…A liquid chromatography method for simultaneous analysis of amino acids, polyamines, catecholeamines and metanephrines in human body fluids after…”
Get full text

Mutational Status of CDKN2A and TP53 Genes in Laryngeal Squamous Cell Carcinoma by Todorova, Teodora A., Jordanov, Stanislav H., Stancheva, Gergana S., Chalakov, Ivan J., Melnicharov, Mincho B., Kunev, Kuncho V., Mitev, Vanio I., Kaneva, Radka P., Goranova, Teodora E.

“…Laryngeal squamous cell carcinoma (LSCC) is the second most common tumour of the head and neck. It is characterized by frequent aberrations in two cell-cycle…”
Get full text

IL-1RN VNTR Polymorphism in Adult Dermatomyositis and Systemic Lupus Erythematosus by Kamenarska, Zornitsa, Dzhebir, Gyulnas, Hristova, Maria, Savov, Alexey, Vinkov, Anton, Kaneva, Radka, Mitev, Vanio, Dourmishev, Lyubomir

“…Polymorphisms in the cytokine genes and their natural antagonists are thought to influence the predisposition to dermatomyositis (DM) and systemic lupus…”
Get full text

Nafion®-Separated Electrode Solutions in Isoelectric Focusing by Naydenov, Cyrill L., Kirazov, Evgeni P., Boyadjiev, Simeon A., Kirazov, Ludmil P., Lozanov, Valentin S., Mitev, Vanio I.

“…In the present paper, we present our results from studies where the electrode solutions were separated from the carrier with the polytetrafluoroethylene-based…”
Get full text

Novel Methods for Controlling the Current During Isoelectric Focusing by Naydenov, Cyrill L, Kirazov, Evgeni P, Lozanov, Valentin S, Kirazov, Ludmil P, Mitev, Vanio I

“…While studying the effect of electrochemical reactions occurring at the electrodes on achievement of steady state in isoelectric focusing (IEF) we observed an…”
Get full text

Electrochemical Reactions During Isoelectric Focusing and Their Role in Establishment of the pH Gradient by Naydenov, Cyrill L, Kirazov, Evgeni P, Lozanov, Valentin S, Kirazov, Ludmil P, Mitev, Vanio I

“…The process occurring as the background to IEF is electrolysis of water. During IEF the yield of water ions decreases, following a non-linear relationship…”
Get full text

Novel MLH1 frameshift mutation in an extended hereditary nonpolyposis colorectal cancer family by Kadiyska, Tanya-Kirilova, Kaneva, Radka-Petrova, Nedin, Dimitar-Georgiev, Alexandrova, Alexandrina-Borisova, Gegova, Antonina-Todorova, Lalchev, Stoyan-Ganchev, Christova, Tatyana, Mitev, Vanio-Ivanov, Horst, Juergen, Bogdanova, Nadja, Kremensky, Ivo-Marinov

“…AIM： To present novel frameshift mutation c.31delC [p.L11X] in the MLH1 gene identified in an extended Bulgarian hereditary non-polyposis colorectal cancer…”
Get full text

Frequency and application of the hot spot BRAF gene mutation (p.V600E) in the diagnostic strategy for Hereditary Nonpolyposis Colorectal Cancer by Kadiyska, Tanya K., PhD, Konstantinova, Darina V., MSc, Atanasov, Venceslav R., MSc, Kremensky, Ivo M., MD, PhD, Mitev, Vanio I., MD, PhD

“…Abstract Background: BRAF somatic mutations were reported with high frequency in sporadic colorectal cancers (CRCs) with microsatellite instability (MSI). The…”
Get full text