Search Results - "Mitchelson, Fernie G."

A class of low‐cost alternatives to kifunensine for increasing high mannose N‐linked glycosylation for monoclonal antibody production in Chinese hamster ovary cells by Brantley, Timothy J., Mitchelson, Fernie G., Khattak, Sarwat F.

“…N‐linked glycosylation of therapeutic monoclonal antibodies is an important product quality attribute for drug safety and efficacy. An increase in the percent…”
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Modulation of transmembrane pressure in manufacturing scale tangential flow filtration N‐1 perfusion seed culture by Karst, Daniel J., Ramer, Kevin, Hughes, Erik H., Jiang, Canping, Jacobs, Pieter J., Mitchelson, Fernie G.

“…Mammalian cells were grown to high density in a 3,000 L culture using perfusion with hollow fibers operated in a tangential flow filtration mode. The…”
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Effect of copper variation in yeast hydrolysate on C‐terminal lysine levels of a monoclonal antibody by Mitchelson, Fernie G., Mondia, Jessica P., Hughes, Erik H.

“…The ability to control charge heterogeneity in monoclonal antibodies is important to demonstrate product quality comparability and consistency. This article…”
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