Search Results - "Mitchell, A. A."
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1
Circadian time signatures of fitness and disease
Published in Science (American Association for the Advancement of Science) (25-11-2016)“…Biological clocks are autonomous anticipatory oscillators that play a critical role in the organization and information processing from genome to whole…”
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2
Estimating Standard Errors in Finance Panel Data Sets: Comparing Approaches
Published in The Review of financial studies (01-01-2009)“…In corporate finance and asset pricing empirical work, researchers are often confronted with panel data. In these data sets, the residuals may be correlated…”
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3
Clocks, Metabolism, and the Epigenome
Published in Molecular cell (27-07-2012)“…Many behaviors and physiological activities in living organisms display circadian rhythms, allowing the organisms to anticipate and prepare for the diurnal…”
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Interconnections between circadian clocks and metabolism
Published in The Journal of clinical investigation (01-08-2021)“…Circadian rhythms evolved through adaptation to daily light/dark changes in the environment; they are believed to be regulated by the core circadian clock…”
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Thiazolidinediones and the Promise of Insulin Sensitization in Type 2 Diabetes
Published in Cell metabolism (07-10-2014)“…Type 2 diabetes is caused by insulin resistance coupled with an inability to produce enough insulin to control blood glucose, and thiazolidinediones (TZDs) are…”
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6
Forming functional fat: a growing understanding of adipocyte differentiation
Published in Nature reviews. Molecular cell biology (01-11-2011)“…Key Points Adipogenesis is a highly regulated process that converts fibroblast-like precursor cells into round and lipid-laden adipocytes. White and brown…”
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7
Integrative regulation of physiology by histone deacetylase 3
Published in Nature reviews. Molecular cell biology (01-02-2019)“…Cell-type-specific gene expression is physiologically modulated by the binding of transcription factors to genomic enhancer sequences, to which chromatin…”
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Unraveling the Regulation of Hepatic Metabolism by Insulin
Published in Trends in endocrinology and metabolism (01-07-2017)“…During insulin-resistant states such as type 2 diabetes mellitus (T2DM), insulin fails to suppress hepatic glucose production but promotes lipid synthesis…”
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9
Maturing of the nuclear receptor family
Published in The Journal of clinical investigation (01-04-2017)“…Members of the nuclear receptor (NR) superfamily of ligand-regulated transcription factors play important roles in reproduction, development, and physiology…”
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Risk of dementia and mild cognitive impairment in older people with subjective memory complaints: meta-analysis
Published in Acta psychiatrica Scandinavica (01-12-2014)“…Objective To investigate whether people with subjective memory complaints (SMC) but no objective deficits are at increased risk of developing mild cognitive…”
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Multidimensional hierarchical self-assembly of amphiphilic cylindrical block comicelles
Published in Science (American Association for the Advancement of Science) (20-03-2015)“…Self-assembly of molecular and block copolymer amphiphiles represents a well-established route to micelles with a wide variety of shapes and gel-like phases…”
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12
Modelling metabolic diseases and drug response using stem cells and organoids
Published in Nature reviews. Endocrinology (01-12-2022)“…Metabolic diseases, including obesity, diabetes mellitus and cardiovascular disease, are a major threat to health in the modern world, but efforts to…”
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13
Transcriptional Control of Circadian Rhythms and Metabolism: A Matter of Time and Space
Published in Endocrine reviews (01-10-2020)“…Abstract All biological processes, living organisms, and ecosystems have evolved with the Sun that confers a 24-hour periodicity to life on Earth. Circadian…”
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14
The Health Risk of Obesity—Better Metrics Imperative
Published in Science (American Association for the Advancement of Science) (23-08-2013)“…The impact of a high BMI on mortality is in question, calling for a rethinking of how metabolic health is assessed. Obesity has increased worldwide; is a major…”
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15
Circadian Metabolism in the Light of Evolution
Published in Endocrine reviews (01-06-2015)“…Circadian rhythm, or daily oscillation, of behaviors and biological processes is a fundamental feature of mammalian physiology that has developed over hundreds…”
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Tugs-of-war in science
Published in The Journal of clinical investigation (15-10-2022)Get full text
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Strelka2: fast and accurate calling of germline and somatic variants
Published in Nature methods (01-08-2018)“…We describe Strelka2 ( https://github.com/Illumina/strelka ), an open-source small-variant-calling method for research and clinical germline and somatic…”
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18
Learning facilitates dual-process face recognition regardless of holistic processing
Published in Memory & cognition (01-08-2023)“…Much evidence suggests that faces are recognized based on their global familiarity in a signal-detection manner. However, experiments drawing this conclusion…”
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Rate of progression of mild cognitive impairment to dementia - meta-analysis of 41 robust inception cohort studies
Published in Acta Psychiatrica Scandinavica (01-04-2009)“…Objective: To quantify the risk of developing dementia in those with mild cognitive impairment (MCI). Method: Meta‐analysis of inception cohort studies…”
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Two-dimensional assemblies from crystallizable homopolymers with charged termini
Published in Nature materials (01-04-2017)“…The creation of shaped, uniform and colloidally stable two-dimensional (2D) assemblies by bottom-up methods represents a challenge of widespread current…”
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