Search Results - "Mitchell, A"

Circadian time signatures of fitness and disease by Bass, Joseph, Lazar, Mitchell A.

“…Biological clocks are autonomous anticipatory oscillators that play a critical role in the organization and information processing from genome to whole…”
Get full text

Estimating Standard Errors in Finance Panel Data Sets: Comparing Approaches by Petersen, Mitchell A.

“…In corporate finance and asset pricing empirical work, researchers are often confronted with panel data. In these data sets, the residuals may be correlated…”
Get full text

Clocks, Metabolism, and the Epigenome by Feng, Dan, Lazar, Mitchell A.

“…Many behaviors and physiological activities in living organisms display circadian rhythms, allowing the organisms to anticipate and prepare for the diurnal…”
Get full text

Interconnections between circadian clocks and metabolism by Guan, Dongyin, Lazar, Mitchell A

“…Circadian rhythms evolved through adaptation to daily light/dark changes in the environment; they are believed to be regulated by the core circadian clock…”
Get full text

Thiazolidinediones and the Promise of Insulin Sensitization in Type 2 Diabetes by Soccio, Raymond E., Chen, Eric R., Lazar, Mitchell A.

“…Type 2 diabetes is caused by insulin resistance coupled with an inability to produce enough insulin to control blood glucose, and thiazolidinediones (TZDs) are…”
Get full text

Forming functional fat: a growing understanding of adipocyte differentiation by Lazar, Mitchell A, Cristancho, Ana G

“…Key Points Adipogenesis is a highly regulated process that converts fibroblast-like precursor cells into round and lipid-laden adipocytes. White and brown…”
Get full text

Integrative regulation of physiology by histone deacetylase 3 by Emmett, Matthew J., Lazar, Mitchell A.

“…Cell-type-specific gene expression is physiologically modulated by the binding of transcription factors to genomic enhancer sequences, to which chromatin…”
Get full text

Unraveling the Regulation of Hepatic Metabolism by Insulin by Titchenell, Paul M, Lazar, Mitchell A, Birnbaum, Morris J

“…During insulin-resistant states such as type 2 diabetes mellitus (T2DM), insulin fails to suppress hepatic glucose production but promotes lipid synthesis…”
Get full text

Maturing of the nuclear receptor family by Lazar, Mitchell A

“…Members of the nuclear receptor (NR) superfamily of ligand-regulated transcription factors play important roles in reproduction, development, and physiology…”
Get full text

Risk of dementia and mild cognitive impairment in older people with subjective memory complaints: meta-analysis by Mitchell, A. J., Beaumont, H., Ferguson, D., Yadegarfar, M., Stubbs, B.

“…Objective To investigate whether people with subjective memory complaints (SMC) but no objective deficits are at increased risk of developing mild cognitive…”
Get full text

Multidimensional hierarchical self-assembly of amphiphilic cylindrical block comicelles by Qiu, Huibin, Hudson, Zachary M., Winnik, Mitchell A., Manners, Ian

“…Self-assembly of molecular and block copolymer amphiphiles represents a well-established route to micelles with a wide variety of shapes and gel-like phases…”
Get full text

Modelling metabolic diseases and drug response using stem cells and organoids by Hu, Wenxiang, Lazar, Mitchell A.

“…Metabolic diseases, including obesity, diabetes mellitus and cardiovascular disease, are a major threat to health in the modern world, but efforts to…”
Get full text

Transcriptional Control of Circadian Rhythms and Metabolism: A Matter of Time and Space by Kim, Yong Hoon, Lazar, Mitchell A

“…Abstract All biological processes, living organisms, and ecosystems have evolved with the Sun that confers a 24-hour periodicity to life on Earth. Circadian…”
Get full text

The Health Risk of Obesity—Better Metrics Imperative by Ahima, Rexford S., Lazar, Mitchell A.

“…The impact of a high BMI on mortality is in question, calling for a rethinking of how metabolic health is assessed. Obesity has increased worldwide; is a major…”
Get full text

Circadian Metabolism in the Light of Evolution by Gerhart-Hines, Zachary, Lazar, Mitchell A

“…Circadian rhythm, or daily oscillation, of behaviors and biological processes is a fundamental feature of mammalian physiology that has developed over hundreds…”
Get full text

Tugs-of-war in science by Lazar, Mitchell A

Get full text

Strelka2: fast and accurate calling of germline and somatic variants by Kim, Sangtae, Scheffler, Konrad, Halpern, Aaron L., Bekritsky, Mitchell A., Noh, Eunho, Källberg, Morten, Chen, Xiaoyu, Kim, Yeonbin, Beyter, Doruk, Krusche, Peter, Saunders, Christopher T.

“…We describe Strelka2 ( https://github.com/Illumina/strelka ), an open-source small-variant-calling method for research and clinical germline and somatic…”
Get full text

Learning facilitates dual-process face recognition regardless of holistic processing by Meltzer, Mitchell A.

“…Much evidence suggests that faces are recognized based on their global familiarity in a signal-detection manner. However, experiments drawing this conclusion…”
Get full text

Rate of progression of mild cognitive impairment to dementia - meta-analysis of 41 robust inception cohort studies by Mitchell, A. J., Shiri-Feshki, M.

“…Objective:  To quantify the risk of developing dementia in those with mild cognitive impairment (MCI). Method:  Meta‐analysis of inception cohort studies…”
Get full text

Two-dimensional assemblies from crystallizable homopolymers with charged termini by He, Xiaoming, Hsiao, Ming-Siao, Boott, Charlotte E., Harniman, Robert L., Nazemi, Ali, Li, Xiaoyu, Winnik, Mitchell A., Manners, Ian

“…The creation of shaped, uniform and colloidally stable two-dimensional (2D) assemblies by bottom-up methods represents a challenge of widespread current…”
Get full text