Search Results - "Mitchelhill, K"

The Akt kinase signals directly to endothelial nitric oxide synthase by Michell, B.J., Griffiths, J.E., Mitchelhill, K.I., Rodriguez-Crespo, I., Tiganis, T., Bozinovski, S., de Montellano, P.R.Ortiz, Kemp, B.E., Pearson, R.B.

“…Endothelial nitric oxide synthase (eNOS) is an important modulator of angiogenesis and vascular tone [1]. It is stimulated by treatment of endothelial cells in…”
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Mammalian AMP-activated protein kinase shares structural and functional homology with the catalytic domain of yeast Snf1 protein kinase by Mitchelhill, K.I, Stapleton, D, Gao, G, House, C, Michell, B, Katsis, F, Witters, L.A, Kemp, B.E

“…The AMP-activated protein kinase is responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It may also regulate…”
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AMP-activated protein kinase phosphorylation of endothelial NO synthase by Chen, Zhi-Ping, Mitchelhill, Ken I, Michell, Belinda J, Stapleton, David, Rodriguez-Crespo, Ignacio, Witters, Lee A, Power, David A, Ortiz de Montellano, Paul R, Kemp, Bruce E

“…The AMP-activated protein kinase (AMPK) in rat skeletal and cardiac muscle is activated by vigorous exercise and ischaemic stress. Under these conditions AMPK…”
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Dealing with energy demand: the AMP-activated protein kinase by Kemp, Bruce E, Mitchelhill, Ken I, Stapleton, David, Michell, Belinda J, Chen, Zhi-Ping, Witters, Lee A

“…The AMP-activated protein kinase (AMPK) is a member of a metabolite-sensing protein kinase family that is found in all eukaryotes. AMPK activity is regulated…”
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Mammalian AMP-activated Protein Kinase Subfamily (∗) by Stapleton, David, Mitchelhill, Ken I., Gao, Guang, Widmer, Jane, Michell, Belinda J., Teh, Trazel, House, Colin M., Fernandez, C. Shamala, Cox, Timothy, Witters, Lee A., Kemp, Bruce E.

“…The mammalian 5′-AMP-activated protein kinase (AMPK) is related to a growing family of protein kinases in yeast and plants that are regulated by nutritional…”
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Mammalian 5'-AMP-activated protein kinase non-catalytic subunits are homologs of proteins that interact with yeast Snf1 protein kinase by Stapleton, D, Gao, G, Michell, B J, Widmer, J, Mitchelhill, K, Teh, T, House, C M, Witters, L A, Kemp, B E

“…The 5'-AMP-activated protein kinase is responsible for the regulation of fatty acid synthesis by phosphorylation and inactivation of acetyl-CoA carboxylase…”
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A potent inhibitor of osteoclastic bone resorption within a highly conserved pentapeptide region of parathyroid hormone-related protein; PTHrP[107-111] by Fenton, A J, Kemp, B E, Hammonds, Jr, R G, Mitchelhill, K, Moseley, J M, Martin, T J, Nicholson, G C

“…We have recently shown that a carboxyl-terminal sequence of parathyroid hormone-related protein, PTHrP[107-139], is a potent direct inhibitor of osteoclastic…”
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Human factor H-related protein 5 (FHR-5). A new complement-associated protein by McRae, J L, Cowan, P J, Power, D A, Mitchelhill, K I, Kemp, B E, Morgan, B P, Murphy, B F

“…A novel human plasma protein has been identified as a universal component of complement deposits, when complement is detected immunohistochemically in vivo…”
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Phosphorylation at the Cyclin-dependent Kinases Site (Thr85) of Parathyroid Hormone-related Protein Negatively Regulates Its Nuclear Localization by Lam, M H, House, C M, Tiganis, T, Mitchelhill, K I, Sarcevic, B, Cures, A, Ramsay, R, Kemp, B E, Martin, T J, Gillespie, M T

“…Parathyroid hormone-related protein (PTHrP) is expressed by a wide variety of cells and is considered to act as a secreted factor; however, evidence is…”
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AMP-activated protein kinase isoenzyme family: subunit structure and chromosomal location by Stapleton, David, Woollatt, Erica, Mitchelhill, Ken I, Nicholl, Jillian K, Fernandez, C.Shamala, Michell, Belinda J, Witters, Lee A, Power, David A, Sutherland, Grant R, Kemp, Bruce E

“…The AMP-activated protein kinase (AMPK) consists of catalytic α and non-catalytic, β and γ (38 kDa) subunits and is responsible for acting as a metabolic…”
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Isoform-specific Purification and Substrate Specificity of the 5′-AMP-activated Protein Kinase by Michell, Belinda J., Stapleton, David, Mitchelhill, Ken I., House, Colin M., Katsis, Frosa, Witters, Lee A., Kemp, Bruce E.

“…The 5′-AMP-activated protein kinase (AMPK) mediates several cellular responses to metabolic stress. Rat liver contains at least two isoforms of this enzyme,…”
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Plasma amino-terminal pro-brain natriuretic peptide: A novel approach to the diagnosis of cardiac dysfunction by Campbell, Duncan J., Mitchelhill, Kenneth I., Schlicht, Stephen M., Booth, Russell J.

“…Background: Heart failure is a common cause of hospitalization and death across the industrialized world. Improving the diagnosis and care of patients with…”
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FHA domain boundaries of the Dun1p and Rad53p cell cycle checkpoint kinases by Hammet, Andrew, Pike, Brietta L., Mitchelhill, Kenneth I., Teh, Trazel, Kobe, Bostjan, House, Colin M., Kemp, Bruce E., Heierhorst, Jörg

“…Dun1p and Rad53p of the budding yeast Saccharomyces cerevisiae are members of a conserved family of cell cycle checkpoint protein kinases that contain…”
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Purification of calcitonin-like peptides from rat brain and pituitary by Hilton, J M, Mitchelhill, K I, Pozvek, G, Dowton, M, Quiza, M, Sexton, P M

“…Accumulating evidence supports the existence of nonthyroidal calcitonin (CT)-like peptides, more similar to fish CTs, which may act as endogenous regulators of…”
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The Myosin-I-Binding Protein Acan125 Binds the SH3 Domain and Belongs to the Superfamily of Leucine-Rich Repeat Proteins by Xu, Pin, Mitchelhill, Ken I., Kobe, Bostjan, Kemp, Bruce E., Zot, Henry G.

“…The SH3 domains of src and other nonreceptor tyrosine kinases have been shown to associate with the motif PXXP, where P and X stand for proline and an…”
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Simplified conjugation chemistry for coupling peptides to F(ab') fragments: autologous red cell agglutination assay for HIV-1 antibodies by Wilson, K M, Catimel, B, Mitchelhill, K I, Kemp, B E

“…The rapid whole blood test, developed for the detection of circulating antibodies to human immunodeficiency virus type 1 (HIV-1), is based on agglutination of…”
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Synapsins as major neuronal Ca2+/S100A1-interacting proteins by Heierhorst, J, Mitchelhill, K I, Mann, R J, Tiganis, T, Czernik, A J, Greengard, P, Kemp, B E

“…The mammalian S100A1 protein can activate the invertebrate myosin-associated giant protein kinase twitchin in a Ca(2+)-dependent manner by more than 1000-fold…”
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Role of the pseudosubstrate sequence in smooth muscle myosin light chain kinase thermal stability by FAUX, M. C, PEARSON, R. B, MITCHELHILL, K. I, KEMP, B. E

“…Smooth muscle myosin light chain kinase (MLCK) is stable in the presence of Ca2+/calmodulin and does not undergo inactivation as reported for skeletal muscle…”
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Autologous red cell agglutination test for antibodies to feline immunodeficiency virus by Wilson, K M, Robinson, W F, Mitchelhill, K I, Bundesen, P G, Kemp, B E

“…The T-lymphotropic lentivirus, feline immunodeficiency virus (FIV) is now recognised as a major viral pathogen affecting domestic cat populations worldwide. A…”
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Effects of opioid peptides containing the sequence of Met5-enkephalin or Leu5-enkephalin on nicotine-induced secretion from bovine adrenal chromaffin cells by Marley, P D, Mitchelhill, K I, Livett, B G

“…Eighteen endogenous opioid peptides, all containing the sequence of either Met5- or Leu5-enkephalin, were tested for their ability to modify nicotine-induced…”
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