Search Results - "Mitcham, Jennifer L"
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Broad neutralization coverage of HIV by multiple highly potent antibodies
Published in Nature (London) (22-09-2011)“…Broadly neutralizing antibodies against highly variable viral pathogens are much sought after to treat or protect against global circulating viruses. Here we…”
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Broad and Potent Neutralizing Antibodies from an African Donor Reveal a New HIV-1 Vaccine Target
Published in Science (American Association for the Advancement of Science) (09-10-2009)“…Broadly neutralizing antibodies (bNAbs), which develop over time in some HIV-1-infected individuals, define critical epitopes for HIV vaccine design. Using a…”
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Human antibodies reveal a protective epitope that is highly conserved among human and nonhuman influenza A viruses
Published in Proceedings of the National Academy of Sciences - PNAS (13-07-2010)“…Influenza remains a serious public health threat throughout the world. Vaccines and antivirals are available that can provide protection from infection…”
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Efficacy and Safety of Treatment With an Anti-M2e Monoclonal Antibody in Experimental Human Influenza
Published in The Journal of infectious diseases (01-04-2015)“…Background. The efficacy of TCN-032, a human monoclonal antibody targeting a conserved epitope on M2e, was explored in experimental human influenza. Methods…”
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Identification of Two Major Sites in the Type I Interleukin-1 Receptor Cytoplasmic Region Responsible for Coupling to Pro-inflammatory Signaling Pathways
Published in The Journal of biological chemistry (18-02-2000)“…Type I interleukin-1 receptor is the prototype for a family of proteins, which play a central role in early responses to injury and infection. The similarity…”
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T1/ST2 Signaling Establishes It as a Member of an Expanding Interleukin-1 Receptor Family (∗)
Published in The Journal of biological chemistry (08-03-1996)“…Through data base searches, we have discovered new proteins that share homology with the signaling domain of the type I interleukin-1 receptor (IL-1RI): human…”
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Chromosomal Localization ofTIL,a Gene Encoding a Protein Related to theDrosophilaTransmembrane Receptor Toll, to Human Chromosome 4p14
Published in Genomics (San Diego, Calif.) (01-03-1996)Get full text
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Chromosomal localization of TIL, a gene encoding a protein related to the Drosophila transmembrane receptor toll, to human chromosome 4p14
Published in Genomics (San Diego, Calif.) (15-03-1996)“…The Drosophila transmembrane receptor Toll and the mammalian interleukin-1 (IL-1) receptor are known to share similarities in both amino-acid sequence and…”
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Analysis of a scrambled gene: the gene encoding α-telomere-binding protein in Oxytricha nova
Published in Genes & development (01-05-1992)“…Following cell mating in ciliates, a copy of the micronuclear genome is processed into a new macronucleus through massive cutting, reordering, splicing,…”
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The actin II-encoding gene in the macronucleus of Oxytricha nova
Published in Gene (24-06-1994)“…The macronucleus of the hypotrichous ciliate Oxytricha nova contains two DNA molecules with sizes of approx. 1.4 (actin II) and approx. 1.6 (actin I) kb that…”
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The micronuclear gene encoding beta-telomere binding protein in Oxytricha nova
Published in The Journal of eukaryotic microbiology (01-09-1994)“…The micronuclear version of the gene encoding beta-telomere binding protein (beta-TBP) in Oxytricha nova has been sequenced and compared to the macronuclear…”
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