Search Results - "Misumi, Yoshio"

A human Dravet syndrome model from patient induced pluripotent stem cells by Higurashi, Norimichi, Uchida, Taku, Lossin, Christoph, Misumi, Yoshio, Okada, Yohei, Akamatsu, Wado, Imaizumi, Yoichi, Zhang, Bo, Nabeshima, Kazuki, Mori, Masayuki X, Katsurabayashi, Shutaro, Shirasaka, Yukiyoshi, Okano, Hideyuki, Hirose, Shinichi

“…Dravet syndrome is a devastating infantile-onset epilepsy syndrome with cognitive deficits and autistic traits caused by genetic alterations in SCN1A gene…”
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A reporter gene system for the precise measurement of promoter activity in Thermus thermophilus HB27 by Fujita, Atsushi, Sato, Takaaki, Koyama, Yoshinori, Misumi, Yoshio

“…We developed a reporter gene system that enables precise analysis of promoter activity in Thermus thermophilus HB27. The reporter vector employs a promoterless…”
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Novel Cis-acting Element GASE Regulates Transcriptional Induction by the Golgi Stress Response by Oku, Masaya, Tanakura, Soichiro, Uemura, Aya, Sohda, Miwa, Misumi, Yoshio, Taniguchi, Mai, Wakabayashi, Sadao, Yoshida, Hiderou

“…When increased production of secretory proteins overwhelms the capacity of the endoplasmic reticulum (ER) and the Golgi apparatus, eukaryotic cells expand…”
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Identification of a soluble isoform of human IL-17RA generated by alternative splicing by Sohda, Miwa, Misumi, Yoshio, Tashiro, Kosuke, Yamazaki, Manabu, Saku, Takashi, Oda, Kimimitsu

“…•An alternative splice variant of human IL-17RA was identified at the mRNA level.•The variant encodes an isoform of IL-17RA lacking the transmembrane…”
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Kv4 Accessory Protein DPPX (DPP6) is a Critical Regulator of Membrane Excitability in Hippocampal CA1 Pyramidal Neurons by Kim, Jinhyun, Nadal, Marcela S, Clemens, Ann M, Baron, Matthew, Jung, Sung-Cherl, Misumi, Yoshio, Rudy, Bernardo, Hoffman, Dax A

“…1 Molecular Neurophysiology and Biophysics Unit, Laboratory of Cellular and Synaptic Neurophysiology, National Institute of Child Health and Human Development,…”
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The Interaction of Two Tethering Factors, p115 and COG complex, is Required for Golgi Integrity by Sohda, Miwa, Misumi, Yoshio, Yoshimura, Shin‐ichiro, Nakamura, Nobuhiro, Fusano, Takami, Ogata, Shigenori, Sakisaka, Shotaro, Ikehara, Yukio

“…The vesicle‐tethering protein p115 functions in endoplasmic reticulum–Golgi trafficking. We explored the function of homologous region 2 (HR2) of the p115 head…”
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Modulation of D-Serine Levels via Ubiquitin-dependent Proteasomal Degradation of Serine Racemase by Dumin, Elena, Bendikov, Inna, Foltyn, Veronika N., Misumi, Yoshio, Ikehara, Yukio, Kartvelishvily, Elena, Wolosker, Herman

“…Mammalian serine racemase is a brain-enriched enzyme that converts l- into d-serine in the nervous system. d-Serine is an endogenous co-agonist at the “glycine…”
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YIPF5 and YIF1A recycle between the ER and the Golgi apparatus and are involved in the maintenance of the Golgi structure by Yoshida, Yumi, Suzuki, Kurumi, Yamamoto, Akitsugu, Sakai, Noriko, Bando, Misako, Tanimoto, Kouji, Yamaguchi, Youko, Sakaguchi, Tomoaki, Akhter, Hasina, Fujii, Gourou, Yoshimura, Shin-ichiro, Ogata, Shigenori, Sohda, Miwa, Misumi, Yoshio, Nakamura, Nobuhiro

“…Yip1p/Yif1p family proteins are five-span transmembrane proteins localized in the Golgi apparatus and the ER. There are nine family members in humans, and…”
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Identification and Characterization of a Novel Golgi Protein, GCP60, That Interacts with the Integral Membrane Protein Giantin by Sohda, M, Misumi, Y, Yamamoto, A, Yano, A, Nakamura, N, Ikehara, Y

“…We demonstrated previously that the integral membrane protein giantin has the Golgi localization signal at the COOH-terminal cytoplasmic domain (Misumi, Y.,…”
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Characterization of YIPF3 and YIPF4, cis-Golgi Localizing Yip Domain Family Proteins by Tanimoto, Kouji, Suzuki, Kurumi, Jokitalo, Eija, Sakai, Noriko, Sakaguchi, Tomoaki, Tamura, Daisuke, Fujii, Gourou, Aoki, Kenji, Takada, Saya, Ishida, Ryuichi, Tanabe, Masako, Itoh, Hideaki, Yoneda, Yukio, Sohda, Miwa, Misumi, Yoshio, Nakamura, Nobuhiro

“…The Yip1 domain family (YIPF) proteins are homologues of yeast Yip1p and Yif1p, which are proposed to function in ER to Golgi transport. Here, we report the…”
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Dynamics of Golgi Matrix Proteins after the Blockage of ER to Golgi Transport by Yoshimura, Shin-ichiro, Yamamoto, Akitsugu, Misumi, Yoshio, Sohda, Miwa, Barr, Francis A., Fujii, Gourou, Shakoori, Abbas, Ohno, Hiroshi, Mihara, Katsuyoshi, Nakamura, Nobuhiro

“…When the ER to Golgi transport is blocked by a GTP-restricted mutant of Sar1p (H79G) in NRK-52E cells, most Golgi resident proteins are transported back into…”
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Identification and Characterization of GCP16, a Novel Acylated Golgi Protein That Interacts with GCP170 by Ohta, Eiji, Misumi, Yoshio, Sohda, Miwa, Fujiwara, Toshiyuki, Yano, Akiko, Ikehara, Yukio

“…GCP170, a member of the golgin family associated with the cytoplasmic face of the Golgi membrane, was found to have a Golgi localization signal at the…”
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Biosynthesis and Characterization of the Brain-Specific Membrane Protein DPPX, a Dipeptidyl Peptidase IV—Related Protein by Kin, Yoshiaki, Misumi, Yoshio, Ikehara, Yukio

“…Dipeptidyl peptidase IV-related protein (DPPX) was found to be preferentially expressed in the brain tissue. We isolated two rat cDNA clones encoding DPPX-S…”
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An Essential Cytoplasmic Domain for the Golgi Localization of Coiled-coil Proteins with a COOH-terminal Membrane Anchor by Misumi, Yoshio, Sohda, Miwa, Tashiro, Akiko, Sato, Hiroshi, Ikehara, Yukio

“…Giantin is a resident Golgi protein that has an extremely long cytoplasmic domain (about 370 kDa) and is anchored to the Golgi membrane by the COOH-terminal…”
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Development of a new host–vector system for colour selection of cloned DNA inserts using a newly designed β-galactosidase gene containing multiple cloning sites in Thermus thermophilus HB27 by Fujita, Atsushi, Misumi, Yoshio

“…We constructed a new Thermus thermophilus cloning vector which enables the colour selection of cloned DNA inserts in the T. thermophilus HB27 host strain…”
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Distinct specificity in the binding of inositol phosphates by pleckstrin homology domains of pleckstrin, RAC-protein kinase, diacylglycerol kinase and a new 130 kDa protein by Takeuchi, Hiroshi, Kanematsu, Takashi, Misumi, Yoshio, Sakane, Fumio, Konishi, Hiroaki, Kikkawa, Ushio, Watanabe, Yutaka, Katan, Matilda, Hirata, Masato

“…The pleckstrin homology domains (PH domains) derived from four different proteins, the N-terminal part of pleckstrin, RAC-protein kinase, diacylglycerol kinase…”
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Nordihydroguaiaretic Acid Blocks Protein Transport in the Secretory Pathway Causing Redistribution of Golgi Proteins into the Endoplasmic Reticulum by Fujiwara, T, Takami, N, Misumi, Y, Ikehara, Y

“…We have investigated the effect of nordihydroguaiaretic acid (NDGA), an inhibitor of lipoxygenase, on the intracellular protein transport and the structure of…”
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Direct targeting of cis-Golgi matrix proteins to the Golgi apparatus by Yoshimura, S I, Nakamura, N, Barr, F A, Misumi, Y, Ikehara, Y, Ohno, H, Sakaguchi, M, Mihara, K

“…The targeting route of newly synthesized GM130 and GRASP65 to the Golgi apparatus was investigated by three different approaches. First, localization of pulse…”
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A new inositol 1,4,5-trisphosphate binding protein similar to phospholipase C-δ1 by KANEMATSU, Takashi, MISUMI, Yoshio, WATANABE, Yutaka, OZAKI, Shoichiro, KOGA, Toshitaka, IWANAGA, Sadaaki, IKEHARA, Yukio, HIRATA, Masato

“…We have reported that two inositol 1,4,5-trisphosphate binding proteins, with molecular masses of 85 and 130 kDa, were purified from rat brain; the former…”
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TNFα triggers release of extracellular vesicles containing TNFR1 and TRADD, which can modulate TNFα responses of the parental cells by Sohda, Miwa, Misumi, Yoshio, Oda, Kimimitsu

“…Tumor necrosis factor-α (TNFα)-induced reactions are effective to maintain homeostasis; however, excessive responses play progressive roles in the pathogenesis…”
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