Search Results - "Missel, Julie Winkel"

The rapid “teabag” method for high-end purification of membrane proteins by Hering, Jenny, Missel, Julie Winkel, Zhang, Liying, Gunnarsson, Anders, Castaldo, Marie, Pedersen, Per Amstrup, Ek, Margareta, Gourdon, Pontus, Snijder, Harm Jan

“…Overproduction and purification of membrane proteins are generally challenging and time-consuming procedures due to low expression levels, misfolding, and low…”
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Targeting Aquaporin-4 Subcellular Localization to Treat Central Nervous System Edema by Kitchen, Philip, Salman, Mootaz M., Halsey, Andrea M., Clarke-Bland, Charlotte, MacDonald, Justin A., Ishida, Hiroaki, Vogel, Hans J., Almutiri, Sharif, Logan, Ann, Kreida, Stefan, Al-Jubair, Tamim, Winkel Missel, Julie, Gourdon, Pontus, Törnroth-Horsefield, Susanna, Conner, Matthew T., Ahmed, Zubair, Conner, Alex C., Bill, Roslyn M.

“…Swelling of the brain or spinal cord (CNS edema) affects millions of people every year. All potential pharmacological interventions have failed in clinical…”
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Human adipose glycerol flux is regulated by a pH gate in AQP10 by Gotfryd, Kamil, Mósca, Andreia Filipa, Missel, Julie Winkel, Truelsen, Sigurd Friis, Wang, Kaituo, Spulber, Mariana, Krabbe, Simon, Hélix-Nielsen, Claus, Laforenza, Umberto, Soveral, Graça, Pedersen, Per Amstrup, Gourdon, Pontus

“…Obesity is a major threat to global health and metabolically associated with glycerol homeostasis. Here we demonstrate that in human adipocytes, the decreased…”
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Structure of the human ClC-1 chloride channel by Wang, Kaituo, Preisler, Sarah Spruce, Zhang, Liying, Cui, Yanxiang, Missel, Julie Winkel, Grønberg, Christina, Gotfryd, Kamil, Lindahl, Erik, Andersson, Magnus, Calloe, Kirstine, Egea, Pascal F, Klaerke, Dan Arne, Pusch, Michael, Pedersen, Per Amstrup, Zhou, Z Hong, Gourdon, Pontus

“…ClC-1 protein channels facilitate rapid passage of chloride ions across cellular membranes, thereby orchestrating skeletal muscle excitability. Malfunction of…”
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Purification and functional comparison of nine human Aquaporins produced in Saccharomyces cerevisiae for the purpose of biophysical characterization by Bjørkskov, Frederik Bühring, Krabbe, Simon Lyngaa, Nurup, Casper Normann, Missel, Julie Winkel, Spulber, Mariana, Bomholt, Julie, Molbaek, Karen, Helix-Nielsen, Claus, Gotfryd, Kamil, Gourdon, Pontus, Pedersen, Per Amstrup

“…The sparse number of high-resolution human membrane protein structures severely restricts our comprehension of molecular physiology and ability to exploit…”
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PcoB is a defense outer membrane protein that facilitates cellular uptake of copper by Li, Ping, Nayeri, Niloofar, Górecki, Kamil, Becares, Eva Ramos, Wang, Kaituo, Mahato, Dhani Ram, Andersson, Magnus, Abeyrathna, Sameera S., Lindkvist‐Petersson, Karin, Meloni, Gabriele, Missel, Julie Winkel, Gourdon, Pontus

“…Copper (Cu) is one of the most abundant trace metals in all organisms, involved in a plethora of cellular processes. Yet elevated concentrations of the element…”
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Characterization of human aquaporin protein-protein interactions using microscale thermophoresis (MST) by Al-Jubair, Tamim, Steffen, Jonas Hyld, Missel, Julie Winkel, Kitchen, Philip, Salman, Mootaz M., Bill, Roslyn M., Gourdon, Pontus, Törnroth-Horsefield, Susanna

“…Aquaporin water channels (AQPs) are membrane proteins that maintain cellular water homeostasis. The interactions between human AQPs and other proteins play…”
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High-yield overproduction and purification of human aquaporins from Pichia pastoris by Al-Jubair, Tamim, Steffen, Jonas Hyld, Missel, Julie Winkel, Kitchen, Philip, Salman, Mootaz M., Bill, Roslyn M., Gourdon, Pontus, Törnroth-Horsefield, Susanna

“…Aquaporins (AQPs) are membrane-bound water channels that play crucial roles in maintaining the water homeostasis of the human body. Here, we present a protocol…”
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Assessing water permeability of aquaporins in a proteoliposome-based stopped-flow setup by Steffen, Jonas Hyld, Missel, Julie Winkel, Al-Jubair, Tamim, Kitchen, Philip, Salman, Mootaz M., Bill, Roslyn M., Törnroth-Horsefield, Susanna, Gourdon, Pontus

“…Aquaporins (AQPs) are water channels embedded in the cell membrane that are critical in maintaining water homeostasis. We describe a protocol for determining…”
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Cyclohexyl-α maltoside as a highly efficient tool for membrane protein studies by Missel, Julie Winkel, Salustros, Nina, Becares, Eva Ramos, Steffen, Jonas Hyld, Laursen, Amalie Gerdt, Garcia, Angelica Struve, Garcia-Alai, Maria M., Kolar, Čeněk, Gourdon, Pontus, Gotfryd, Kamil

“…Membrane proteins (MPs) constitute a large fraction of the proteome, but exhibit physicochemical characteristics that impose challenges for successful sample…”
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The role of phosphorylation in calmodulin-mediated gating of human AQP0 by Kreida, Stefan, Roche, Jennifer Virginia, Missel, Julie Winkel, Al-Jubair, Tamim, Hagströmer, Carl Johan, Wittenbecher, Veronika, Linse, Sara, Gourdon, Pontus, Törnroth-Horsefield, Susanna

“…Aquaporin-0 (AQP0) is the main water channel in the mammalian lens and is involved in accommodation and maintaining lens transparency. AQP0 binds the…”
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The role of water coordination in the pH-dependent gating of hAQP10 by Truelsen, Sigurd Friis, Missel, Julie Winkel, Gotfryd, Kamil, Pedersen, Per Amstrup, Gourdon, Pontus, Lindorff-Larsen, Kresten, Hélix-Nielsen, Claus

“…Human aquaporin 10 (hAQP10) is an aquaglyceroporin that assists in maintaining glycerol flux in adipocytes during lipolysis at low pH. Hence, a molecular…”
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