Search Results - "Misic, Ana M."
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Stress during pregnancy alters temporal and spatial dynamics of the maternal and offspring microbiome in a sex-specific manner
Published in Scientific reports (07-03-2017)“…The microbiome is a regulator of host immunity, metabolism, neurodevelopment, and behavior. During early life, bacterial communities within maternal gut and…”
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Variable gene expression and parasite load predict treatment outcome in cutaneous leishmaniasis
Published in Science translational medicine (20-11-2019)“…Patients infected with develop chronic lesions that often fail to respond to treatment with antiparasite drugs. To determine whether genes whose expression is…”
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Diet-induced remission in chronic enteropathy is associated with altered microbial community structure and synthesis of secondary bile acids
Published in Microbiome (31-08-2019)“…The microbiome has been implicated in the initiation and persistence of inflammatory bowel disease. Despite the fact that diet is one of the most potent…”
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Infection-Induced Intestinal Dysbiosis Is Mediated by Macrophage Activation and Nitrate Production
Published in mBio (28-05-2019)“…Oral infection of C57BL/6J mice with results in a marked bacterial dysbiosis and the development of severe pathology in the distal small intestine that is…”
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Remodeling of the maternal gut microbiome during pregnancy is shaped by parity
Published in Microbiome (27-06-2021)“…Abstract Background The maternal microbiome has emerged as an important factor in gestational health and outcome and is associated with risk of preterm birth…”
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Glial-cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence
Published in Nature (London) (21-07-2016)“…Neurotrophic factors produced by enteric glia in response to microbiota and alarmin cues regulate IL-22 production by group 3 innate lymphoid cells in the gut;…”
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Commensal Microbes Induce Serum IgA Responses that Protect against Polymicrobial Sepsis
Published in Cell host & microbe (14-03-2018)“…Serum immunoglobulin A (IgA) antibodies are readily detected in mice and people, but the mechanisms underlying the induction of serum IgA and its role in host…”
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Crystal Structure of the Deinococcus radiodurans Single-Stranded DNA-Binding Protein Suggests a Mechanism for Coping with DNA Damage
Published in Proceedings of the National Academy of Sciences - PNAS (08-06-2004)“…Single-stranded DNA (ssDNA)-binding (SSB) proteins are uniformly required to bind and protect single-stranded intermediates in DNA metabolic pathways. All…”
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Longitudinal Evaluation of the Skin Microbiome and Association with Microenvironment and Treatment in Canine Atopic Dermatitis
Published in Journal of investigative dermatology (01-06-2016)“…Host-microbe interactions may play a fundamental role in the pathogenesis of atopic dermatitis, a chronic relapsing inflammatory skin disorder characterized by…”
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Cutaneous Leishmaniasis Induces a Transmissible Dysbiotic Skin Microbiota that Promotes Skin Inflammation
Published in Cell host & microbe (12-07-2017)“…Skin microbiota can impact allergic and autoimmune responses, wound healing, and anti-microbial defense. We investigated the role of skin microbiota in…”
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P. aeruginosa PilT Structures with and without Nucleotide Reveal a Dynamic Type IV Pilus Retraction Motor
Published in Journal of molecular biology (30-07-2010)“…Type IV pili are bacterial extracellular filaments that can be retracted to create force and motility. Retraction is accomplished by the motor protein PilT…”
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The shared microbiota of humans and companion animals as evaluated from Staphylococcus carriage sites
Published in Microbiome (23-01-2015)“…Staphylococcus aureus and other coagulase-positive staphylococci (CPS) colonize skin and mucous membrane sites and can cause skin and soft tissue infections…”
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Risk factors for antimicrobial resistance among Staphylococcus isolated from pets living with a patient diagnosed with methicillin‐resistant Staphylococcus aureus infection
Published in Zoonoses and public health (01-08-2022)“…It has been suggested that pets play a critical role in the maintenance of methicillin‐resistant (MR) and multidrug‐resistant (MDR) Staphylococcus spp. in the…”
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Genome sequencing reveals strain dynamics of methicillin-resistant Staphylococcus aureus in the same household in the context of clinical disease in a person and a dog
Published in Veterinary microbiology (18-11-2015)“…•We identified cases of MRSA in a dog owner and his dog through a controlled trial.•We sampled the dog owner, dog, a household member, and home surfaces over…”
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Crystal Structures of the Pilus Retraction Motor PilT Suggest Large Domain Movements and Subunit Cooperation Drive Motility
Published in Structure (London) (01-03-2007)“…PilT is a hexameric ATPase required for bacterial type IV pilus retraction and surface motility. Crystal structures of ADP- and ATP-bound Aquifex aeolicus PilT…”
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Culture-independent Profiling of the Fecal Microbiome to Identify Microbial Species Associated with a Diarrheal Outbreak in Immunocompromised Mice
Published in Comparative medicine (01-08-2018)“…Immunocompromised mice are used frequently in biomedical research, in part because they accommodate the engraftment and study of primary human cells within a…”
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Complete Genome Sequence and Methylome of Staphylococcus schleiferi, an Important Cause of Skin and Ear Infections in Veterinary Medicine
Published in Genome announcements (Washington, DC) (10-09-2015)“…Staphylococcus schleiferi, a Gram-positive and coagulase-variable organism, is an opportunistic human pathogen and a major cause of skin and soft tissue…”
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Divergent Isoprenoid Biosynthesis Pathways in Staphylococcus Species Constitute a Drug Target for Treating Infections in Companion Animals
Published in mSphere (01-09-2016)“…species are a leading cause of skin and soft tissue infections in humans and animals, and the antibiotics used to treat these infections are often the same…”
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P067 INVESTIGATION OF THE PRESENCE OF MYCOBACTERIUM AVIUM SSP. PARATUBERCULOSIS IN CHILDREN WITH CROHN DISEASE USING QUANTITATIVE DNA SEQUENCE-BASED APPROACHES
Published in Inflammatory bowel diseases (18-01-2018)“…Abstract Background Mycobacterium avium ssp. paratuberculosis (MAP) has been suspected to play a role in Crohn disease (CD) pathogenesis. Prior studies of MAP…”
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