Search Results - "Mishra, Siddhartha Kumar"
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Pancreatic lipase related protein 1 as a potential target in triglyceride breakdown: A molecular docking studies with in vitro appraisal
Published in Results in Chemistry (01-01-2023)“…[Display omitted] Targeting obesity by altering the absorption of dietary triglycerides by inhibiting the pancreatic lipase is an interesting exploration. We…”
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Protective and therapeutic potential of ginger (Zingiber officinale) extract and [6]‐gingerol in cancer: A comprehensive review
Published in Phytotherapy research (01-10-2018)“…Natural dietary agents have attracted considerable attention due to their role in promoting health and reducing the risk of diseases including cancer. Ginger,…”
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The phytochemical, biological, and medicinal attributes of phytoecdysteroids: An updated review
Published in Acta pharmaceutica Sinica. B (01-07-2021)“…The phytoecdysteroids (PEs) comprise a large group of biologically-active plant steroids, which have structures similar to those of insect-molting hormones…”
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A systematic assessment of stress insomnia as the high-risk factor for cervical cancer and interplay of cervicovaginal microbiome
Published in Frontiers in cellular and infection microbiology (06-12-2022)“…Cervical cancer is a dreaded form of cancer in women, the fourth most common cancer, with around 0.3 million females suffering from this disease worldwide…”
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Naringenin suppresses aluminum-induced experimental hepato-nephrotoxicity in mice through modulation of oxidative stress and inflammation
Published in Toxicological research (Seoul) (2024)“…Aluminum is a widely used metal substance in daily life activities that has been shown to cause severe hepato-nephrotoxicity with long-term exposure. Natural…”
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Orally administered aqueous extract of Inonotus obliquus ameliorates acute inflammation in dextran sulfate sodium (DSS)-induced colitis in mice
Published in Journal of ethnopharmacology (28-09-2012)“…Chaga mushroom (Inonotus obliquus) has been used in folk medicine to treat several disorders through its various biological functions. I. obliquus is claimed…”
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An updated literature-based review: phytochemistry, pharmacology and therapeutic promises of Nigella sativa L
Published in Oriental pharmacy and experimental medicine (01-06-2019)“…An in depth review on Nigella sativa and its derived constituents has been necessitated which has been sketched in this paper from the research reports…”
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A Perspective on Emerging Therapeutic Interventions for COVID-19
Published in Frontiers in public health (03-07-2020)“…Coronaviruses are enveloped positive-sense RNA viruses with an unusual large RNA genome and a unique replication mechanism, which are characterized by…”
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Antitumoral effects of [6]-gingerol [(S)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone] in sarcoma 180 cells through cytogenetic mechanisms
Published in Biomedicine & pharmacotherapy (01-06-2020)“…[Display omitted] •[6]-Gingerol [(S)-5-hydroxy-1-(4-hydroxy-3-methoxyphenyl)-3-decanone] is a phenolic substance with several pharmacological…”
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Sesquiterpene Alcohol Cedrol Chemosensitizes Human Cancer Cells and Suppresses Cell Proliferation by Destabilizing Plasma Membrane Lipid Rafts
Published in Frontiers in cell and developmental biology (21-01-2021)“…Chemosensitization of cancer cells with small molecules may improve the therapeutic index of antitumoral agents by making tumor cells sensitive to the drug…”
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Modulation of intracellular calcium levels by calcium lactate affects colon cancer cell motility through calcium-dependent calpain
Published in PloS one (28-01-2015)“…Cancer cell motility is a key phenomenon regulating invasion and metastasis. Focal adhesion kinase (FAK) plays a major role in cellular adhesion and metastasis…”
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Inonotus obliquus aqueous extract prevents histopathological alterations in liver induced by environmental toxicant Microcystin
Published in Current research in pharmacology and drug discovery (01-01-2022)“…Environmental toxicants like microcystins are known to adversely impact liver physiology and lead to the increased risk for abnormal liver function and even…”
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Association of polymorphisms and haplotypes in the insulin-like growth factor 1 receptor (IGF1R) gene with the risk of breast cancer in Korean women
Published in PloS one (02-01-2014)“…The insulin-like growth factor (IGF) signaling pathway plays an important role in cancer biology. The IGF 1 receptor (IGF1R) overexpression has been associated…”
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Prevalence, risk factors and virological profile of chronic hepatitis b virus infection in pregnant women in India
Published in Journal of medical virology (01-06-2011)“…A large program was conducted by the Government of India to study the prevalence and profile of chronic hepatitis B virus (HBV) infection and its risk factors…”
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Midazolam induces cellular apoptosis in human cancer cells and inhibits tumor growth in xenograft mice
Published in Molecules and cells (01-09-2013)“…Midazolam is a widely used anesthetic of the benzodiazepine class that has shown cytotoxicity and apoptosisinducing activity in neuronal cells and lymphocytes…”
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Naringenin mitigates aluminum toxicity‐induced learning memory impairments and neurodegeneration through amelioration of oxidative stress
Published in Journal of biochemical and molecular toxicology (01-05-2024)“…Aluminum chloride (AlCl3) is a potent neurotoxic substance known to cause memory impairment and oxidative stress‐dependent neurodegeneration. Naringenin (NAR)…”
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Naringenin ameliorates aluminum toxicity-induced testicular dysfunctions in mice by suppressing oxidative stress and histopathological alterations
Published in Systems biology in reproductive medicine (03-09-2023)“…Environmental aluminum intoxication has shown increasingly alarming negative consequences on reproductive health. This needs mechanistic exploration and…”
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Naringenin mitigates nanoparticulate-aluminium induced neuronal degeneration in brain cortex and hippocampus through downregulation of oxidative stress and neuroinflammation
Published in Neurochemistry international (01-09-2024)“…Alumunium usage and toxicity has been a global concern especially an increased use of nanoparticulated aluminum (Al-NPs) products from the environment and the…”
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Beta‐caryophyllene attenuates experimental hepatocellular carcinoma through downregulation of oxidative stress and inflammation
Published in Journal of biochemical and molecular toxicology (01-10-2024)“…Hepatocellular carcinoma (HCC) is caused by various factors including toxic substances and xenobiotics. Numerous treatment strategies are used to address…”
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Autonomic neuronal modulations in cardiac arrhythmias: Current concepts and emerging therapies
Published in Physiology & behavior (15-05-2024)“…•Cardiac arrhythmias, atrial filtration and ventricular tachycardia, mainly caused by the autonomic nervous system.•Conventional strategies have been overcome…”
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