Search Results - "Mishev, Kiril"
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Disruption of endocytosis through chemical inhibition of clathrin heavy chain function
Published in Nature chemical biology (01-06-2019)“…Clathrin-mediated endocytosis (CME) is a highly conserved and essential cellular process in eukaryotic cells, but its dynamic and vital nature makes it…”
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Hormonomic Changes Driving the Negative Impact of Broomrape on Plant Host Interactions with Arbuscular Mycorrhizal Fungi
Published in International journal of molecular sciences (20-12-2021)“…Belowground interactions of plants with other organisms in the rhizosphere rely on extensive small-molecule communication. Chemical signals released from host…”
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Small Sized Yet Powerful: Nuclear Distribution C Proteins in Plants
Published in Plants (Basel) (31-12-2023)“…The family of Nuclear Distribution C (NudC) proteins plays a pivotal and evolutionarily conserved role in all eukaryotes. In animal systems, these proteins…”
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Mitochondrial uncouplers inhibit clathrin-mediated endocytosis largely through cytoplasmic acidification
Published in Nature communications (08-06-2016)“…ATP production requires the establishment of an electrochemical proton gradient across the inner mitochondrial membrane. Mitochondrial uncouplers dissipate…”
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Metabolic footprints in phosphate-starved plants
Published in Physiology and molecular biology of plants (01-05-2023)“…Plants’ requirement of Phosphorus (P) as an essential macronutrient is obligatory for their normal growth and metabolism. Besides restricting plants’ primary…”
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The Diverse Salt-Stress Response of Arabidopsis ctr1-1 and ein2-1 Ethylene Signaling Mutants Is Linked to Altered Root Auxin Homeostasis
Published in Plants (Basel) (27-02-2021)“…We explored the interplay between ethylene signals and the auxin pool in roots exposed to high salinity using wild-type plants (Col-0), and the…”
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Uncovering the Interrelation between Metabolite Profiles and Bioactivity of In Vitro- and Wild-Grown Catmint ( Nepeta nuda L.)
Published in Metabolites (01-10-2023)“…L. is a medicinal plant enriched with secondary metabolites serving to attract pollinators and deter herbivores. Phenolics and iridoids of have been…”
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Fluorescent castasterone reveals BRI1 signaling from the plasma membrane
Published in Nature chemical biology (06-05-2012)Get full text
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Regulation of Arabidopsis brassinosteroid receptor BRI1 endocytosis and degradation by plant U-box PUB12/PUB13-mediated ubiquitination
Published in Proceedings of the National Academy of Sciences - PNAS (20-02-2018)“…Plants largely rely on plasma membrane (PM)-resident receptor-like kinases (RLKs) to sense extracellular and intracellular stimuli and coordinate cell…”
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The brassinosteroid chemical toolbox
Published in Current opinion in plant biology (01-12-2014)“…•Brassinosteroid research benefited from several chemical biology approaches.•Small molecules target biosynthesis as well as signaling.•Analogs of brassinolide…”
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Ethylene signaling in salt-stressed Arabidopsis thaliana ein2-1 and ctr1-1 mutants – A dissection of molecular mechanisms involved in acclimation
Published in Plant physiology and biochemistry (01-10-2021)“…To pinpoint ethylene-mediated molecular mechanisms involved in the adaptive response to salt stress we conducted a comparative study of Arabidopsis thaliana…”
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Fluorescent castasterone reveals BRI1 signaling from the plasma membrane
Published in Nature chemical biology (01-06-2012)“…Brassinosteroids (BRs) are plant growth hormones that bind the brassinosteroid receptor (BRI1) and activate its kinase domain. Exploration of BRI1-BR…”
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The Hordeum bulbosum 25S-18S rDNA region: comparison with Hordeum vulgare and other Triticeae
Published in Zeitschrift für Naturforschung C. A journal of biosciences (26-11-2019)“…and are two closely related barley species, which share a common H genome. has two nucleolar organizer regions (NORs), while the NOR of is only one. We…”
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The Diverse Salt-Stress Response of Arabidopsis ctr1-1 and ein2-1Ethylene Signaling Mutants Is Linked to Altered Root Auxin Homeostasis
Published in Plants (Basel) (01-03-2021)Get full text
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15
The Inhibitor Endosidin 4 Targets SEC7 Domain-Type ARF GTPase Exchange Factors and Interferes with Subcellular Trafficking in Eukaryotes
Published in The Plant cell (01-10-2018)“…The trafficking of subcellular cargos in eukaryotic cells crucially depends on vesicle budding, a process mediated by ARF-GEFs (ADP-ribosylation factor guanine…”
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Sequence-Specific Protein Aggregation Generates Defined Protein Knockdowns in Plants
Published in Plant physiology (Bethesda) (01-06-2016)“…Protein aggregation is determined by short (5–15 amino acids) aggregation-prone regions (APRs) of the polypeptide sequence that self-associate in a specific…”
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Nonselective Chemical Inhibition of Sec7 Domain-Containing ARF GTPase Exchange Factors
Published in The Plant cell (01-10-2018)“…Small GTP-binding proteins from the ADP-ribosylation factor (ARF) family are important regulators of vesicle formation and cellular trafficking in all…”
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Mapping of unmethylated sites in rDNA repeats in barley NOR deletion line
Published in Journal of plant physiology (20-10-2016)“…Extensive cytosine methylation is characteristic of plant rDNA. Evidence exists, however, that the active rRNA genes are less methylated. In this work we…”
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Sequence-Specific Protein Aggregation Generates Defined Protein Knockdowns in Plants1[OPEN]
Published in Plant physiology (Bethesda) (04-05-2016)“…A protein knockdown method based on expression of specific aggregation-prone peptides derived from the targeted proteins. Protein aggregation is determined by…”
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Darkness Affects Differentially the Expression of Plastid-Encoded Genes and Delays the Senescence-Induced Down-Regulation of Chloroplast Transcription in Cotyledons of Cucurbita pepo L. (Zucchini)
Published in Zeitschrift für Naturforschung C. A journal of biosciences (01-04-2011)“…In contrast to differentiated leaves, the regulatory mechanisms of chloroplast gene expression in darkened cotyledons have not been elucidated. Although some…”
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