Search Results - "Mish, Michael R."

Asymmetric Dipolar Cycloadditions of Me3SiCHN2. Synthesis of a Novel Class of Amino Acids:  Azaprolines by Mish, Michael R, Guerra, Francisco M, Carreira, Erick M

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Preparation and biological evaluation of 1′-cyano-2′-C-methyl pyrimidine nucleosides as HCV NS5B polymerase inhibitors by Mish, Michael R., Cho, Aesop, Kirschberg, Thorsten, Xu, Jie, Sebastian Zonte, C., Fenaux, Martijn, Park, Yeojin, Babusis, Darius, Feng, Joy Y., Ray, Adrian S., Kim, Choung U.

“…The first synthesis of 1′-cyano-2′-C-methyl pyrimidine nucleosides is described. Anti-HCV activity of these nucleosides and their nucleotide phosphoramidate…”
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Discovery of a 2′-fluoro-2′-C-methyl C-nucleotide HCV polymerase inhibitor and a phosphoramidate prodrug with favorable properties by Kirschberg, Thorsten A., Metobo, Sammy, Clarke, Michael O., Aktoudianakis, Vangelis, Babusis, Darius, Barauskas, Ona, Birkus, Gabriel, Butler, Thomas, Byun, Daniel, Chin, Gregory, Doerffler, Edward, Edwards, Thomas E., Fenaux, Martijn, Lee, Rick, Lew, Willard, Mish, Michael R., Murakami, Eisuke, Park, Yeojin, Squires, Neil H., Tirunagari, Neeraj, Wang, Ting, Whitcomb, Mark, Xu, Jie, Yang, Huiling, Ye, Hong, Zhang, Lijun, Appleby, Todd C., Feng, Joy Y., Ray, Adrian S., Cho, Aesop, Kim, Choung U.

“…[Display omitted] A series of 2′-fluorinated C-nucleosides were prepared and tested for anti-HCV activity. Among them, the triphosphate of…”
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Synthesis and characterization of 1′-C-cyano-2′-fluoro-2′-C-methyl pyrimidine nucleosides as HCV polymerase inhibitors by Kirschberg, Thorsten A., Mish, Michael R., Zhang, Lijun, Squires, Neil H., Wang, Ke-Yu, Cho, Aesop, Feng, Joy Y., Fenaux, Martijn, Babusis, Darius, Park, Yeojin, Ray, Adrian S., Kim, Choung U.

“…[Display omitted] The first synthesis of 1′-C-CN, 2′-F, 2′-C-Me pyrimidines is described. Anti-HCV activity was assessed and compared to the 1′-C-CN, 2′-C-Me…”
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Asymmetric Dipolar Cycloadditions of Me 3 SiCHN 2 . Synthesis of a Novel Class of Amino Acids:  Azaprolines by Mish, Michael R., Guerra, Francisco M., Carreira, Erick M.

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