Search Results - "Miserez, A. R."

Zurich Fabry study - prevalence of Fabry disease in young patients with first cryptogenic ischaemic stroke or TIA by Sarikaya, H., Yilmaz, M., Michael, N., Miserez, A. R., Steinmann, B., Baumgartner, R. W.

“…Background and purpose The etiology of stroke in young patients remains undetermined in up to half of the cases. Data on prevalence of Fabry disease (FD) in…”
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DIAgnosis and Management Of familial hypercholesterolemia in a Nationwide Design (DIAMOND-FH): Prevalence in Switzerland, clinical characteristics and the diagnostic value of clinical scores by Miserez, A.R., Martin, F.J., Spirk, D.

“…In Switzerland, the prevalence of familial hypercholesterolemia (FH) due to pathogenic apolipoprotein B-100 gene (APOB) variants was known, but not the…”
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The discrete and combined effect of SREBP-2 and SCAP isoforms in the control of plasma lipids among familial hypercholesterolaemia patients by Durst, R., Jansen, A., Erez, G., Bravdo, R., Butbul, E., Ben Avi, L., Shpitzen, S., Lotan, C., Leitersdorf, E., Defesche, J., Friedlander, Y., Meiner, V., Miserez, A.R.

“…Hypercholesterolaemia is a major risk factor for atherosclerosis. Cholesterol is modulated by genetic and environmental factors. An important regulatory…”
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Estimation of tissue hypothyroidism by a new clinical score : Evaluation of patients with various grades of hypothyroidism and controls by ZULEWSKI, H, MÜLLER, B, EXER, P, MISEREZ, A. R, STAUB, J.-J

“…The classical signs and symptoms of hypothyroidism were reevaluated in the light of the modern laboratory tests for thyroid function. We analyzed 332 female…”
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Apolipoprotein E genotypes and cognitive functions in healthy elderly persons by Staehelin, H. B., Perrig-Chiello, P., Mitrache, C., Miserez, A. R., Perrig, W. J.

“…Objectives‐ We investigated whether apoE genotypes correlate with cognitive functions in clinically healthy persons. Methods ‐ In 1993 and 1995, we measured…”
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Identification of mutations in the gene encoding sterol regulatory element binding protein (SREBP)-2 in hypercholesterolaemic subjects by Muller, P Y, Miserez, A R

“…Human cells maintain their cholesterol homeostasis by regulated cleavage of membrane bound transcription factors, so-called sterol regulatory element binding…”
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Quantitative EEG and apolipoprotein E-genotype improve classification of patients with suspected Alzheimer’s disease by Hatz, F, Benz, N, Hardmeier, M, Zimmermann, R, Rueegg, S, Schindler, C, Miserez, A.R, Gschwandtner, U, Monsch, A.U, Fuhr, P

“…Highlights • Quantitative EEG (qEEG) distinguishes patients with mild cognitive impairment and patients with dementia due to Alzheimer’s disease in the…”
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Differences in the Phenotypic Characteristics of Subjects With Familial Defective Apolipoprotein B-100 and Familial Hypercholesterolemia by Miserez, Andre R, Keller, Ulrich

“…Familial defective apolipoprotein B-100 (FDB) is a recently identified autosomal-dominantly inherited disorder caused by a point mutation in the apolipoprotein…”
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Development of tachyphylaxis on statin treatment by AR, Miserez, U, Keller, R, Mirsaidi

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High prevalence of familial defective apolipoprotein B-100 in Switzerland by Miserez, A R, Laager, R, Chiodetti, N, Keller, U

“…Familial defective apolipoprotein B-100 (FDB) is caused by a single G-to-A substitution at nucleotide 10,708 leading to an arginine to glutamine change at…”
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Structure of the Human Gene Encoding Sterol Regulatory Element Binding Protein 2 (SREBF2) by Miserez, André R., Cao, Guoqing, Probst, Lori C., Hobbs, Helen H.

“…Sterol-regulatory element binding protein (SREBP) 1 and SREBP2 are ubiquitously expressed transcription factors that play key roles in the regulation of…”
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No Association Between Plasma Lipoprotein(a) Concentrations and the Presence or Absence of Coronary Atherosclerosis in African-Americans by Moliterno, David J, Jokinen, Eero V, Miserez, Andre R, Lange, Richard A, Willard, John E, Boerwinkle, Eric, Hillis, L. David, Hobbs, Helen H

“…Elevated plasma concentrations of lipoprotein(a) [Lp(a)] are associated with coronary atherosclerosis in Caucasians. Although African-Americans have a higher…”
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Apolipoprotein E3Basel: new insights into a highly conserved protein region by Miserez, A. R., Scharnagl, H., Muller, P. Y., Mirsaidi, R., Stähelin, H. B., Monsch, A., März, W., Hoffmann, M. M.

“…Background Apolipoprotein E is important for the receptor‐mediated uptake of triglyceride‐rich lipoproteins. Mutations in the gene encoding apolipoprotein E…”
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TSH-controlled L-thyroxine therapy reduces cholesterol levels and clinical symptoms in subclinical hypothyroidism : A double blind, placebo-controlled trial (Basel thyroid study) by MEIER, Christian, STAUB, Jean-Jacques, ROTH, Carl-Bénédict, GUGLIELMETTI, Merih, KUNZ, Maya, MISEREZ, André R, DREWE, Jürgen, HUBER, Peter, HERZOG, Richard, MÜLLER, Beat

“…This study evaluated the effect of physiological, TSH-guided, L-thyroxine treatment on serum lipids and clinical symptoms in patients with subclinical…”
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Apolipoprotein E genotype in senile dementia with tangles differs from Alzheimer's disease by Tolnay, M., Villoz, N., Probst, A., Miserez, A. R.

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Familial defective apolipoprotein B-100: a mutation emerged in the Mesolithic period by Miserez, A.R., Muller, P.Y.

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Molecular Biocomputing Suite: a word processor add-in for the analysis and manipulation of nucleic acid and protein sequence data by Muller, P Y, Studer, E, Miserez, A R

“…In all fields of molecular biology, researchers are increasingly challenged by experiments planned and evaluated on the basis of nucleic acid and protein…”
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Prediction of the therapeutic response to simvastatin by pretreatment lipid concentrations in 2082 subjects by MISEREZ, A. R, ROSSI, F. A, KELLER, U

“…2082 hypercholesterolemic subjects were treated with simvastatin for 12 weeks. In 530 patients the dose was increased after 6 weeks from 10 to 20 mg because of…”
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RepGene: a spreadsheet template for the management of reporter gene assays by Muller, P Y, Barella, L, Miserez, A R

“…One of the most powerful techniques in molecular biology is the controlled expression of specific proteins by transfection of eukaryotic cells. This method has…”
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Simvastatin reduces activation of normal platelets by LDL isolated from patients with familial hypercholesterolaemia and familial defective apolipoprotein B by TSAKIRIS, D. A, KELLER, U, ZULEWSKI, H, MISEREZ, A. R, WOLF, F, MARBET, G. A

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