Search Results - "Mischke, Mona"
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More than just a gut instinct-the potential interplay between a baby's nutrition, its gut microbiome, and the epigenome
Published in American journal of physiology. Regulatory, integrative and comparative physiology (15-06-2013)“…Substantial evidence links early postnatal nutrition to the development of obesity later in life. However, the molecular mechanisms of this connection must be…”
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An Alu element-associated hypermethylation variant of the POMC gene is associated with childhood obesity
Published in PLoS genetics (01-03-2012)“…The individual risk for common diseases not only depends on genetic but also on epigenetic polymorphisms. To assess the role of epigenetic variations in the…”
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The effect of dietary lipid quality in early life on serum LysoPC(18:2) levels and their association with adult blood glucose levels in intrauterine growth restricted rats
Published in Nutrition & metabolism (27-11-2021)“…Abstract Being born small-for-gestational-age, especially with subsequent catch-up growth, is associated with impaired metabolic health in later-life. We…”
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The Role of the Gut Microbiota in the Effects of Early-Life Stress and Dietary Fatty Acids on Later-Life Central and Metabolic Outcomes in Mice
Published in mSystems (28-06-2022)“…Early-life stress (ELS) leads to increased vulnerability for mental and metabolic disorders. We have previously shown that a low dietary ω-6/ω-3…”
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Maternal Western-style high fat diet induces sex-specific physiological and molecular changes in two-week-old mouse offspring
Published in PloS one (05-11-2013)“…Maternal diet is associated with the development of metabolism-related and other non-communicable diseases in offspring. Underlying mechanisms, functional…”
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Sexually dimorphic characteristics of the small intestine and colon of prepubescent C57BL/6 mice
Published in Biology of sex differences (29-08-2014)“…There is increasing appreciation for sexually dimorphic effects, but the molecular mechanisms underlying these effects are only partially understood. In the…”
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The Gut Microbiota and their Metabolites: Potential Implications for the Host Epigenome
Published in Advances in experimental medicine and biology (01-01-2016)“…The gut microbiota represents a metabolically active biomass of up to 2 kg in adult humans. Microbiota-derived molecules significantly contribute to the host…”
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Early‐Life Exposure to Dietary Large Phospholipid‐Coated Lipid Droplets Improves Markers of Metabolic and Immune Function in Adipose Tissue Later in Life in a Mouse Model
Published in Molecular nutrition & food research (01-01-2024)“…Scope Human milk (HM) is considered optimal nutrition for infants, beneficially programming adult health outcomes including reduced obesity risk. Early life…”
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Sex differences in lipid metabolism are affected by presence of the gut microbiota
Published in Scientific reports (07-09-2018)“…Physiological processes are differentially regulated between men and women. Sex and gut microbiota have each been demonstrated to regulate host metabolism, but…”
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Early-life origin of intestinal inflammatory disorders
Published in Nutrition reviews (01-03-2017)“…A growing body of evidence supports the concept of perinatal programming through which the perinatal environment affects the development of the fetus and…”
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Early life nutrition influences susceptibility to chronic inflammatory colitis in later life
Published in Scientific reports (02-12-2019)“…The first thousand days of life are a critical time of development in humans during which the risk profile for diseases in later life can be modified…”
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Specific synbiotics in early life protect against diet‐induced obesity in adult mice
Published in Diabetes, obesity & metabolism (01-06-2018)“…Aims The metabolic state of human adults is associated with their gut microbiome. The symbiosis between host and microbiome is initiated at birth, and early…”
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Maternal exposure to a Western‐style diet causes differences in intestinal microbiota composition and gene expression of suckling mouse pups
Published in Molecular nutrition & food research (01-01-2017)“…Scope The long‐lasting consequences of nutritional programming during the early phase of life have become increasingly evident. The effects of maternal…”
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