Search Results - "Mischel, P. S."

Bevacizumab and chemotherapy for recurrent glioblastoma : A single-institution experience by NGHIEMPHU, P. L, LIU, W, NELSON, S. F, ELASHOFF, R, CLOUGHESY, T. F, LEE, Y, THAN, T, GRAHAM, C, LAI, A, GREEN, R. M, POPE, W. B, LIAU, L. M, MISCHEL, P. S

“…Bevacizumab has been shown to be effective in the treatment of recurrent glioblastoma in combination with chemotherapy compared with historic controls but not…”
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Analysis of Oncogenic Signaling Networks in Glioblastoma Identifies ASPM as a Molecular Target by Horvath, S., Zhang, B., Carlson, M., Lu, K. V., Zhu, S., Felciano, R. M., Laurance, M. F., Zhao, W., Qi, S., Chen, Z., Lee, Y., Scheck, A. C., Liau, L. M., Wu, H., Geschwind, D. H., Febbo, P. G., Kornblum, H. I., Cloughesy, T. F., Nelson, S. F., Mischel, P. S.

“…Glioblastoma is the most common primary malignant brain tumor of adults and one of the most lethal of all cancers. Patients with this disease have a median…”
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Extrachromosomal DNA—relieving heredity constraints, accelerating tumour evolution by Bailey, C., Shoura, M.J., Mischel, P.S., Swanton, C.

“…Oncogene amplification on extrachromosomal DNA (ecDNA) provides a mechanism by which cancer cells can rapidly adapt to changes in the tumour microenvironment…”
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Molecular pathology in adult high-grade gliomas: from molecular diagnostics to target therapies by Masui, K., Cloughesy, T. F., Mischel, P. S.

“…K. Masui, T. F. Cloughesy and P. S. Mischel (2012) Neuropathology and Applied Neurobiology38, 271–291 Molecular pathology in adult high‐grade gliomas: from…”
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Review: Molecular pathology in adult high-grade gliomas: from molecular diagnostics to target therapies by MASUI, K, CLOUGHESYT, T. F, MISCHEL, P. S

“…The classification of malignant gliomas is moving from a morphology-based guide to a system built on molecular criteria. The development of a genomic landscape…”
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Oncogenic extrachromosomal DNA identification using whole-genome sequencing from formalin-fixed glioblastomas by Noorani, I, Luebeck, J, Rowan, A, Grönroos, E, Barbe, V, Fabian, M, Nicoll, J A R, Boche, D, Bafna, V, Mischel, P S, Swanton, C

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Probabilistic radiographic atlas of glioblastoma phenotypes by Ellingson, B M, Lai, A, Harris, R J, Selfridge, J M, Yong, W H, Das, K, Pope, W B, Nghiemphu, P L, Vinters, H V, Liau, L M, Mischel, P S, Cloughesy, T F

“…Tumor location is a significant prognostic factor in glioblastoma, which may reflect the genetic profile of tumor precursor cells. The purpose of the current…”
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A tale of two approaches: complementary mechanisms of cytotoxic and targeted therapy resistance may inform next-generation cancer treatments by Masui, Kenta, Gini, Beatrice, Wykosky, Jill, Zanca, Ciro, Mischel, Paul S, Furnari, Frank B, Cavenee, Webster K

“…Chemotherapy and molecularly targeted approaches represent two very different modes of cancer treatment and each is associated with unique benefits and…”
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Cerebral cortical dysplasia associated with pediatric epilepsy. Review of neuropathologic features and proposal for a grading system by Mischel, P S, Nguyen, L P, Vinters, H V

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Coccidioidomycosis of the Central Nervous System: Neuropathological and Vasculopathic Manifestations and Clinical Correlates by Mischel, Paul S., Vinters, Harry V.

“…Infection due to the fungus Coccidioides immitis, which is endemic to the southwestern United States, is currently occurring in epidemic proportions. Although…”
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Glut3 addiction is a druggable vulnerability for a molecularly defined subpopulation of glioblastoma by Cosset, É, Ilmjärv, S., Dutoit, V., Elliott, K., von Schalscha, T., Reiss, A., Camargo, M.F., Moroishi, T., Seguin, L., Gomez, G., Moo, J.S., Preynat-Seauve, O., Krause, K.H., Chneiweiss, H., Guan, K.L., Dietrich, P.Y., Weis, S.M., Mischel, P.S., Cheresh, D.A.

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Siomycin A targets brain tumor stem cells partially through a MELK-mediated pathway by Nakano, Ichiro, Joshi, Kaushal, Visnyei, Koppany, Hu, Bin, Watanabe, Momoko, Lam, Diana, Wexler, Eric, Saigusa, Kuniyasu, Nakamura, Yuko, Laks, Dan R., Mischel, Paul S., Viapiano, Mariano, Kornblum, Harley I.

“…Glioblastoma multiforme (GBM) is a devastating disease, and the current therapies have only palliative effect. Evidence is mounting to indicate that brain…”
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mTOR signaling in glioblastoma: lessons learned from bench to bedside by Akhavan, D., Cloughesy, T. F., Mischel, P. S.

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Lymphomatosis cerebri presenting as a rapidly progressive dementia: clinical, neuroimaging and pathologic findings by Bakshi, R, Mazziotta, J C, Mischel, P S, Jahan, R, Seligson, D B, Vinters, H V

“…Primary central nervous system lymphoma (PCNSL) usually presents with clinical and neuroimaging findings consistent with single or multiple intracranial mass…”
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Analysis of the phosphatidylinositol 3'-kinase signaling pathway in glioblastoma patients in vivo by CHOE, Gheeyoung, HORVATH, Steve, CLOUGHESY, Timothy F, CROSBY, Katherine, SELIGSON, David, PALOTIE, Aarno, INGE, Landon, SMITH, Bradley L, SAWYERS, Charles L, MISCHEL, Paul S

“…Deregulated signaling through the phosphatidylinositol 3'-kinase (PI3K) pathway is common in many types of cancer, including glioblastoma. Dissecting the…”
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Childhood generalized and mesial temporal epilepsies demonstrate different amounts and patterns of hippocampal neuron loss and mossy fibre synaptic reorganization by Mathern, Gary W., Babb, Thomas L., Mischel, Paul S., Vinters, Harry V., Pretorius, James K., Leite, Joao P., Peacock, Warwick J.

“…Summary In this study, we determined whether childhood seizures were associated with hippocampal neuron loss and mossy fibre synaptic reorganization and if…”
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Gene expression profiling identifies molecular subtypes of gliomas by SHAI, Ruty, TAO SHI, KREMEN, Thomas J, HORVATH, Steve, LIAU, Linda M, CLOUGHESY, Timothy F, MISCHEL, Paul S, NELSON, Stanley F

“…Identification of distinct molecular subtypes is a critical challenge for cancer biology. In this study, we used Affymetrix high-density oligonucleotide arrays…”
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Hyperacute thermal lesions: MR imaging evaluation of development in the brain by Farahani, K, Mischel, P S, Black, K L, De Salles, A A, Anzai, Y, Lufkin, R B

“…To determine the natural time course of development of hyperacute thermal lesions in the brain. Ten interstitial lesions were created in five rabbit brains…”
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Identification of molecular subtypes of glioblastoma by gene expression profiling by MISCHEL, Paul S, SHAI, Ruty, CLOUGHESY, Timothy F, NELSON, Stanley F, TAO SHI, HORVATH, Steve, LU, Kan V, GHEEYOUNG CHOE, SELIGSON, David, KREMEN, Thomas J, PALOTIE, Aarno, LIAU, Linda M

“…Epidermal growth factor receptor (EGFR) overexpression occurs in nearly 50% of cases of glioblastoma (GBM), but its clinical and biological implications are…”
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Bilateral neuropathologic changes in a child with hemimegalencephaly by Jahan, Reza, Mischel, Paul S., Curran, John G., Peacock, Warwick J., Shields, Donald W., Vinters, Harry V.

“…Evaluation of a 7-month-old girl with developmental delay and intractable seizures revealed hemispheric asymmetry and an enlarged right cerebral hemisphere…”
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