Search Results - "Misch, Martin"

A vaccine targeting mutant IDH1 in newly diagnosed glioma by Platten, Michael, Bunse, Lukas, Wick, Antje, Bunse, Theresa, Le Cornet, Lucian, Harting, Inga, Sahm, Felix, Sanghvi, Khwab, Tan, Chin Leng, Poschke, Isabel, Green, Edward, Justesen, Sune, Behrens, Geoffrey A., Breckwoldt, Michael O., Freitag, Angelika, Rother, Lisa-Marie, Schmitt, Anita, Schnell, Oliver, Hense, Jörg, Misch, Martin, Krex, Dietmar, Stevanovic, Stefan, Tabatabai, Ghazaleh, Steinbach, Joachim P., Bendszus, Martin, von Deimling, Andreas, Schmitt, Michael, Wick, Wolfgang

“…Mutated isocitrate dehydrogenase 1 ( IDH1 ) defines a molecularly distinct subtype of diffuse glioma 1 – 3 . The most common IDH1 mutation in gliomas affects…”
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T2 mapping of molecular subtypes of WHO grade II/III gliomas by Kern, Maike, Auer, Timo Alexander, Picht, Thomas, Misch, Martin, Wiener, Edzard

“…According to the new WHO classification from 2016, molecular profiles have shown to provide reliable information about prognosis and treatment response. The…”
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Clinical implementation of a 3D4K-exoscope (Orbeye) in microneurosurgery by Rösler, Judith, Georgiev, Stefan, Roethe, Anna L., Chakkalakal, Denny, Acker, Güliz, Dengler, Nora F., Prinz, Vincent, Hecht, Nils, Faust, Katharina, Schneider, Ulf, Bayerl, Simon, Czabanka, Marcus, Misch, Martin, Onken, Julia, Vajkoczy, Peter, Picht, Thomas

“…Exoscopic surgery promises alleviation of physical strain, improved intraoperative visualization and facilitation of the clinical workflow. In this prospective…”
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Predictive MGMT status in a homogeneous cohort of IDH wildtype glioblastoma patients by Radke, Josefine, Koch, Arend, Pritsch, Fabienne, Schumann, Elisa, Misch, Martin, Hempt, Claudia, Lenz, Klaus, Löbel, Franziska, Paschereit, Fabienne, Heppner, Frank L, Vajkoczy, Peter, Koll, Randi, Onken, Julia

“…Methylation of the O(6)-Methylguanine-DNA methyltransferase (MGMT) promoter is predictive for treatment response in glioblastoma patients. However, precise…”
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Adjuvant radiotherapy improves progression-free survival in intracranial atypical meningioma by Hemmati, Saman Moritz, Ghadjar, Pirus, Grün, Arne, Badakhshi, Harun, Zschaeck, Sebastian, Senger, Carolin, Acker, Güliz, Misch, Martin, Budach, Volker, Kaul, David

“…Meningiomas are the most common primary tumors of the central nervous system. In patients with WHO grade I meningiomas no adjuvant therapy is recommended after…”
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Patient Reported Outcome (PRO) Among High-Grade Glioma Patients Receiving TTFields Treatment: A Two Center Observational Study by Onken, Julia, Goerling, Ute, Heinrich, Marcel, Pleissner, Stephanie, Krex, Dietmar, Vajkoczy, Peter, Misch, Martin

“…Study design: A two center, observational study. Introduction: Patient reported outcome (PRO) plays an increasingly important role in the evaluation of novel…”
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MRI-Based Risk Assessment for Incomplete Resection of Brain Metastases by Rosenstock, Tizian, Pöser, Paul, Wasilewski, David, Bauknecht, Hans-Christian, Grittner, Ulrike, Picht, Thomas, Misch, Martin, Onken, Julia Sophie, Vajkoczy, Peter

“…Recent studies demonstrated that gross total resection of brain metastases cannot always be achieved. Subtotal resection (STR) can result in an early…”
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Optical Characterization of Sodium Fluorescein In Vitro and Ex Vivo by Xu, Ran, Teich, Wanda, Frenzel, Florian, Hoffmann, Katrin, Radke, Josefine, Rösler, Judith, Faust, Katharina, Blank, Anne, Brandenburg, Susan, Misch, Martin, Vajkoczy, Peter, Onken, Julia Sophie, Resch-Genger, Ute

“…The utilization of fluorescein-guided biopsies and resection has been recently discussed as a suitable strategy to improve and expedite operative techniques…”
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Locally dose-escalated radiotherapy may improve intracranial local control and overall survival among patients with glioblastoma by Zschaeck, Sebastian, Wust, Peter, Graf, Reinhold, Misch, Martin, Onken, Julia, Ghadjar, Pirus, Badakhshi, Harun, Florange, Julian, Budach, Volker, Kaul, David

“…The dismal overall survival (OS) prognosis of glioblastoma, even after trimodal therapy, can be attributed mainly to the frequent incidence of intracranial…”
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AMPLIFY-NEOVAC: a randomized, 3-arm multicenter phase I trial to assess safety, tolerability and immunogenicity of IDH1-vac combined with an immune checkpoint inhibitor targeting programmed death-ligand 1 in isocitrate dehydrogenase 1 mutant gliomas by Bunse, Lukas, Rupp, Anne-Kathleen, Poschke, Isabel, Bunse, Theresa, Lindner, Katharina, Wick, Antje, Blobner, Jens, Misch, Martin, Tabatabai, Ghazaleh, Glas, Martin, Schnell, Oliver, Gempt, Jens, Denk, Monika, Reifenberger, Guido, Bendszus, Martin, Wuchter, Patrick, Steinbach, Joachim P, Wick, Wolfgang, Platten, Michael

“…Isocitrate dehydrogenase (IDH) mutations are disease-defining mutations in IDH-mutant astrocytomas and IDH-mutant and 1p/19q-codeleted oligodendrogliomas. In…”
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Association of F18-fluoro-ethyl-tyrosin uptake and 5-aminolevulinic acid-induced fluorescence in gliomas by Stockhammer, Florian, Misch, Martin, Horn, Peter, Koch, Arend, Fonyuy, Nyuyki, Plotkin, Michail

“…Purpose Malignant gliomas are highly infiltrative tumours with a fatal prognosis. F18-fluoroethyl-tyrosine (FET)-positron emission tomography (PET) often…”
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Glioma patients in outpatient care-optimization of psychosocial care in neuro-oncological patients (GLIOPT): Protocol for a cluster randomized controlled trial by Renovanz, Mirjam, Hippler, Melina, Voss, Martin, Wehinger, Jens, Keßler, Almuth F, Gempt, Jens, Nadji-Ohl, Minou, Weiß Lucas, Carolin, Rapp, Marion, Misch, Martin, Coburger, Jan, Mehlitz, Marcus, Meixensberger, Jürgen, Keric, Naureen, Tabatabai, Ghazaleh, Blettner, Maria, Schranz, Melanie, Singer, Susanne

“…Patients with high-grade gliomas (HGG) often suffer from high distress and require psychosocial support. However, due to neurological and neurocognitive…”
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The role of surgery in IDH wildtype diffuse astrocytomas by Krenzlin, Harald, Lange, Felipa, Dauth, Alice, Kalasauskas, Darius, Freyschlag, Christian, Schnell, Oliver, Misch, Martin, Brelie, Christian von der, Krigers, Aleksandrs, Rohde, Veit, Vajkoczy, Peter, Jürgen, Beck, Thomé, Claudius, Ringel, Florian, Keric, Naureen

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RARE-44. ONE YEAR WITH OPTUNE® IN ROUTINE USE: FIRST REPORT ON CLINICAL EXPERIENCES IN GERMANY by Misch, Martin, Onken, Julia

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Augmented reality visualization in brain lesions: a prospective randomized controlled evaluation of its potential and current limitations in navigated microneurosurgery by Roethe, Anna L., Rösler, Judith, Misch, Martin, Vajkoczy, Peter, Picht, Thomas

“…Background Augmented reality (AR) has the potential to support complex neurosurgical interventions by including visual information seamlessly. This study…”
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Acceptance and compliance of TTFields treatment among high grade glioma patients by Onken, Julia, Staub-Bartelt, Franziska, Vajkoczy, Peter, Misch, Martin

“…Background Tumor treating fields (TTFields) significantly prolong both progression-free and overall survival in patients with newly diagnosed glioblastoma…”
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Lomustine-temozolomide combination therapy versus standard temozolomide therapy in patients with newly diagnosed glioblastoma with methylated MGMT promoter (CeTeG/NOA–09): a randomised, open-label, phase 3 trial by Herrlinger, Ulrich, Tzaridis, Theophilos, Mack, Frederic, Steinbach, Joachim Peter, Schlegel, Uwe, Sabel, Michael, Hau, Peter, Kortmann, Rolf-Dieter, Krex, Dietmar, Grauer, Oliver, Goldbrunner, Roland, Schnell, Oliver, Bähr, Oliver, Uhl, Martin, Seidel, Clemens, Tabatabai, Ghazaleh, Kowalski, Thomas, Ringel, Florian, Schmidt-Graf, Friederike, Suchorska, Bogdana, Brehmer, Stefanie, Weyerbrock, Astrid, Renovanz, Miriam, Bullinger, Lars, Galldiks, Norbert, Vajkoczy, Peter, Misch, Martin, Vatter, Hartmut, Stuplich, Moritz, Schäfer, Niklas, Kebir, Sied, Weller, Johannes, Schaub, Christina, Stummer, Walter, Tonn, Jörg-Christian, Simon, Matthias, Keil, Vera C, Nelles, Michael, Urbach, Horst, Coenen, Martin, Wick, Wolfgang, Weller, Michael, Fimmers, Rolf, Schmid, Matthias, Hattingen, Elke, Pietsch, Torsten, Coch, Christoph, Glas, Martin

“…There is an urgent need for more effective therapies for glioblastoma. Data from a previous unrandomised phase 2 trial suggested that lomustine-temozolomide…”
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Safety and Tolerance of D,L-Methadone in Combination with Chemotherapy in Patients with Glioma by Onken, Julia, Friesen, Claudia, Vajkoczy, Peter, Misch, Martin

“…D,L-Methadone increases sensitivity toward chemotherapy of different tumor cell populations. We evaluated the safety and tolerance of additional use of…”
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NCOG-41. REAL WORLD EXPERIENCE WITH TTFIELDS WITH EMPHASIS ON THERAPY COMPLIANCE by Jelgersma, Claudius, Akkas, Gülsüm, Alsolivany, Joan, Wasilewski, David, Gastl, Bastian, Vajkoczy, Peter, Misch, Martin, Kaul, David, Bullinger, Lars, Onken, Julia

“…Abstract Tumor Treating Fields (TTF) therapy has emerged as a significant adjunctive component in the treatment of high-grade tumors following its validation…”
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Monitor-based exoscopic 3D4k neurosurgical interventions: a two-phase prospective-randomized clinical evaluation of a novel hybrid device by Roethe, Anna L., Landgraf, Philipp, Schröder, Torsten, Misch, Martin, Vajkoczy, Peter, Picht, Thomas

“…Background Promoting a disruptive innovation in microsurgery, exoscopes promise alleviation of physical strain and improved image quality through digital…”
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