Search Results - "Misbaer, Anke"
-
1
Branch-restricted localization of phosphatase Prl-1 specifies axonal synaptogenesis domains
Published in Science (American Association for the Advancement of Science) (03-05-2019)“…Central nervous system (CNS) circuit development requires subcellular control of synapse formation and patterning of synapse abundance. We identified the…”
Get full text
Journal Article -
2
Axon morphogenesis and maintenance require an evolutionary conserved safeguard function of Wnk kinases antagonizing Sarm and Axed
Published in Neuron (Cambridge, Mass.) (15-09-2021)“…The molecular and cellular mechanisms underlying complex axon morphogenesis are still poorly understood. We report a novel, evolutionary conserved function for…”
Get full text
Journal Article -
3
TREM2 Agonism Affects Human Microglia Response in the Presence of Amyloid Pathology In Vivo
Published in Alzheimer's & dementia (01-12-2023)“…Background Pharmacological activation of TREM2 represents a novel therapeutic approach to slow Alzheimer´s disease (AD) progression. Mutations in microglial…”
Get full text
Journal Article -
4
Nuclear import of the DSCAM‐cytoplasmic domain drives signaling capable of inhibiting synapse formation
Published in The EMBO journal (15-03-2019)“…DSCAM and DSCAML1 are immunoglobulin and cell adhesion‐type receptors serving important neurodevelopmental functions including control of axon growth,…”
Get full text
Journal Article