Search Results - "Misaki, Toshinori"
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Necessary and Sufficient Role for a Mitosis Skip in Senescence Induction
Published in Molecular cell (03-07-2014)“…Senescence is a state of permanent growth arrest and is a pivotal part of the antitumorigenic barrier in vivo. Although the tumor suppressor activities of p53…”
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Usp7-dependent histone H3 deubiquitylation regulates maintenance of DNA methylation
Published in Scientific reports (03-03-2017)“…Uhrf1-dependent histone H3 ubiquitylation plays a crucial role in the maintenance of DNA methylation via the recruitment of the DNA methyltransferase Dnmt1 to…”
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Retinoic acid stimulates transcription of the rat SHARP-2 gene via multiple pathways
Published in Journal of biochemistry (Tokyo) (01-09-2021)“…Abstract Members of the enhancer of split- and hairy-related protein (SHARP) family, SHARP-1 and SHARP-2, are basic helix−loop−helix transcriptional repressors…”
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The replication foci targeting sequence (RFTS) of DNMT1 functions as a potent histone H3 binding domain regulated by autoinhibition
Published in Biochemical and biophysical research communications (12-02-2016)“…DNA methyltransferase 1 (DNMT1) plays an essential role in propagation of the DNA methylation pattern to daughter cells. The replication foci targeting…”
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Mitotic phosphorylation of MPP8 by cyclin-dependent kinases regulates chromatin dissociation
Published in Biochemical and biophysical research communications (22-03-2013)“…► Heterochromatin protein MPP8 dissociates from chromatin during early mitosis. ► MPP8 is phosphorylated by CDK1-Cyclin B1 in vivo and in vitro. ► MPP8 with…”
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Mammal-specific H2A Variant, H2ABbd, Is Involved in Apoptotic Induction via Activation of NF-κB Signaling Pathway
Published in The Journal of biological chemistry (25-04-2014)“…Histone variants play specific roles in maintenance and regulation of chromatin structures. H2ABbd, an H2A variant, possesses a highly divergent structure…”
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