Search Results - "Mirzaie, Mehdi"
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A compartmental model that predicts the effect of social distancing and vaccination on controlling COVID-19
Published in Scientific reports (14-04-2021)“…The understanding of the interaction between disease dynamics and human behavior is an important and essential point to control infectious. Disease outbreak…”
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2
Identification of native protein structures captured by principal interactions
Published in BMC bioinformatics (21-11-2019)“…Evaluation of protein structure is based on trustworthy potential function. The total potential of a protein structure is approximated as the summation of all…”
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3
A mathematical model of honey bee colony dynamics to predict the effect of pollen on colony failure
Published in PloS one (22-11-2019)“…The decline in colony populations of the honey bee, known as the Colony Collapse Disorder (CCD), is a global concern. Numerous studies have reported possible…”
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Bipartite network models to design combination therapies in acute myeloid leukaemia
Published in Nature communications (19-04-2022)“…Combination therapy is preferred over single-targeted monotherapies for cancer treatment due to its efficiency and safety. However, identifying effective drug…”
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Nkx3-1 and Fech genes might be switch genes involved in pituitary non-functioning adenoma invasiveness
Published in Scientific reports (22-10-2021)“…Non-functioning pituitary adenomas (NFPAs) are typical pituitary macroadenomas in adults associated with increased mortality and morbidity. Although pituitary…”
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Rps27a might act as a controller of microglia activation in triggering neurodegenerative diseases
Published in PloS one (17-09-2020)“…Neurodegenerative diseases (NDDs) are increasing serious menaces to human health in the recent years. Despite exhibiting different clinical phenotypes and…”
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Publisher Correction: Nkx3-1 and Fech genes might be switch genes involved in pituitary non-functioning adenoma invasiveness
Published in Scientific reports (14-12-2021)Get full text
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A logic-based dynamic modeling approach to explicate the evolution of the central dogma of molecular biology
Published in PloS one (21-12-2017)“…It is nearly half a century past the age of the introduction of the Central Dogma (CD) of molecular biology. This biological axiom has been developed and…”
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Three-way interaction model to trace the mechanisms involved in Alzheimer's disease transgenic mice
Published in PloS one (21-09-2017)“…Alzheimer's disease (AD) is the most common cause for dementia in human. Currently, more than 46 million people in the world suffer from AD and it is estimated…”
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Metabolomic signature of amino acids in plasma of patients with non-segmental Vitiligo
Published in Metabolomics (01-10-2021)“…Introduction Vitiligo pathogenesis is complicated, and several possibilities were suggested. However, it is well-known that the metabolism of pigments plays a…”
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IMMAN: an R/Bioconductor package for Interolog protein network reconstruction, mapping and mining analysis
Published in BMC bioinformatics (12-02-2019)“…Reconstruction of protein-protein interaction networks (PPIN) has been riddled with controversy for decades. Particularly, false-negative and -positive…”
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Identification of key genes and convergent pathways disrupted in autism spectrum disorder via comprehensive bioinformatic analysis
Published in Informatics in medicine unlocked (2021)“…Autism spectrum disorder (ASD) is a complex heterogeneous condition with multifactorial etiology. Despite hundreds of genes found to be associated with ASD,…”
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An insight to HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) pathogenesis; evidence from high-throughput data integration and meta-analysis
Published in Retrovirology (30-12-2019)“…Human T-lymphotropic virus 1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a progressive disease of the central nervous system that…”
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Designing patient-oriented combination therapies for acute myeloid leukemia based on efficacy/toxicity integration and bipartite network modeling
Published in Oncogenesis (New York, NY) (01-03-2024)“…Acute myeloid leukemia (AML), a heterogeneous and aggressive blood cancer, does not respond well to single-drug therapy. A combination of drugs is required to…”
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Role of Surface Electrocardiography in Differentiation between Obstructive and Non-Obstructive Hypertrophic Cardiomyopathy
Published in Journal of Tehran University Heart Center (2023)“…Electrocardiography (ECG), as an easily accessible modality, is usually helpful in hypertrophic cardiomyopathy (HCM) diagnosis. The purpose of this study was…”
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IrGO: Iranian traditional medicine General Ontology and knowledge base
Published in Journal of biomedical semantics (16-04-2021)“…Iranian traditional medicine, also known as Persian Medicine, is a holistic school of medicine with a long prolific history. It describes numerous concepts and…”
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Can We Assume the Gene Expression Profile as a Proxy for Signaling Network Activity?
Published in Biomolecules (Basel, Switzerland) (03-06-2020)“…Studying relationships among gene products by expression profile analysis is a common approach in systems biology. Many studies have generalized the outcomes…”
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Proteomics Analysis of Trastuzumab Toxicity in the H9c2 Cardiomyoblast Cell Line and its Inhibition by Carvedilol
Published in Current pharmaceutical biotechnology (01-01-2020)“…Heart dysfunctions are the major complications of trastuzumab in patients with Human Epidermal growth factor Receptor-2 (HER2)-positive breast cancers. In this…”
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Systems Biomedicine of Rabies Delineates the Affected Signaling Pathways
Published in Frontiers in microbiology (07-11-2016)“…The prototypical neurotropic virus, rabies, is a member of the Rhabdoviridae family that causes lethal encephalomyelitis. Although there have been a plethora…”
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Hydrophobic residues can identify native protein structures
Published in Proteins, structure, function, and bioinformatics (01-04-2018)“…Evaluation of protein structures needs a trustworthy potential function. Although several knowledge‐based potential functions exist, the impact of different…”
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