Search Results - "Mirvish, S S"

Role of N-nitroso compounds (NOC) and N-nitrosation in etiology of gastric, esophageal, nasopharyngeal and bladder cancer and contribution to cancer of known exposures to NOC by Mirvish, Sidney S.

“…The questions of whether and how N-nitroso compounds (NOC) may be inducing cancer in humans are discussed. The principal subjects covered include…”
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Public Health Implications of Smokeless Tobacco Use as a Harm Reduction Strategy by Savitz, David A, Meyer, Roger E, Tanzer, Jason M, Mirvish, Sidney S, Lewin, Freddi

“…Harm reduction strategies involve promoting a product that has adverse health consequences as a substitute for one that has more severe adverse health…”
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N-Nitroso compounds in the gastrointestinal tract of rats and in the feces of mice with induced colitis or fed hot dogs or beef by Mirvish, Sidney S., Haorah, James, Zhou, Lin, Hartman, Melissa, Morris, Chantey R., Clapper, Marge L.

“…Because colonic N-nitroso compounds (NOC) may be a cause of colon cancer, we determined total NOC levels by Walters’ method in the gastrointestinal tract and…”
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Determination of Total N-Nitroso Compounds and Their Precursors in Frankfurters, Fresh Meat, Dried Salted Fish, Sauces, Tobacco, and Tobacco Smoke Particulates by Haorah, James, Zhou, Lin, Wang, Xiaojie, Xu, Guoping, Mirvish, Sidney S

“…Total N-nitroso compounds (NOC) and NOC precursors (NOCP) were determined in extracts of food and tobacco products. Following Walters' method, NOC were…”
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Supercritical fluid technology based large porous celecoxib–PLGA microparticles do not induce pulmonary fibrosis and sustain drug delivery and efficacy for several weeks following a single dose by Dhanda, Devender S., Tyagi, Puneet, Mirvish, Sidney S., Kompella, Uday B.

“…Although pulmonary dosing of large porous particles has been shown to sustain drug delivery for a few days, there are no reports on safety or long term…”
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Partial Purification from Hot Dogs of N-Nitroso Compound Precursors and Their Mutagenicity after Nitrosation by Zhou, Lin, Haorah, James, Perini, Fulvio, Carmella, Steven G, Shibamoto, Takayuki, Mirvish, Sidney S

“…Hot dogs contain apparent N-nitroso compounds (ANC) and ANC precursors (ANCP). ANCP purification was followed by nitrosation, sulfamic acid treatment, and…”
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Comparative Analysis of Tobacco-Specific Nitrosamines and Total N-Nitroso Compounds in Moldovan Cigarette Tobacco by Stepanov, Irina, Hecht, Stephen S, Mirvish, Sidney S, Gonta, Maria

“…While previous studies have evaluated levels of tobacco-specific nitrosamines (TSNA) and total N-nitroso compounds (NOC) in tobacco, there are no reports in…”
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Total N-nitroso compounds and their precursors in hot dogs and in the gastrointestinal tract and feces of rats and mice: possible etiologic agents for colon cancer by Mirvish, Sidney S, Haorah, James, Zhou, Lin, Clapper, Marge L, Harrison, Kathryn L, Povey, Andrew C

“…We review evidence that red and processed meat are causes of colon cancer and that processed meat is a risk factor for childhood cancer and type 2 diabetes…”
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Experimental evidence for inhibition of N-nitroso compound formation as a factor in the negative correlation between vitamin C consumption and the incidence of certain cancers by Mirvish, S S

“…Ascorbic acid (ASC) consumption is negatively correlated with the incidence of certain cancers. This is a review and update of the theory, which has recently…”
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Gastric juice protects against the development of esophageal adenocarcinoma in the rat by Ireland, A P, Peters, J H, Smyrk, T C, DeMeester, T R, Clark, G W, Mirvish, S S, Adrian, T E

“…The authors investigate the effects of gastric juice on tumorigenesis in a rat model of esophageal adenocarcinoma. In rats treated with the carcinogen…”
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Effects of vitamins C and E on N-nitroso compound formation, carcinogenesis, and cancer by Mirvish, S S

“…The properties of N-nitroso compounds (NNC) and of vitamins C and E are briefly described. The author reviews the ability of vitamins C and E to inhibit NNC…”
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Calcium and α-tocopherol suppress cured-meat promotion of chemically induced colon carcinogenesis in rats and reduce associated biomarkers in human volunteers by Pierre, Fabrice HF, Martin, Océane CB, Santarelli, Raphaelle L, Taché, Sylviane, Naud, Nathalie, Guéraud, Françoise, Audebert, Marc, Dupuy, Jacques, Meunier, Nathalie, Attaix, Didier, Vendeuvre, Jean-Luc, Mirvish, Sidney S, Kuhnle, Gunter CG, Cano, Noel, Corpet, Denis E

“…Background: Processed meat intake has been associated with increased colorectal cancer risk. We have shown that cured meat promotes carcinogen-induced…”
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Studies on experimental animals involving surgical procedures and/or nitrosamine treatment related to the etiology of esophageal adenocarcinoma by Mirvish, Sidney S

“…After a brief review of the epidemiology and etiology of lower esophageal adenocarcinoma (EAC), this paper describes long-term experiments on animals (mostly…”
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Duodenoesophageal reflux and the development of esophageal adenocarcinoma in rats by Attwood, S E, Smyrk, T C, DeMeester, T R, Mirvish, S S, Stein, H J, Hinder, R A

“…The carcinogenic effect of duodenoesophageal reflux, gastroesophageal reflux, and nitrosamines was studied in the rat esophagus. Twenty male Sprague-Dawley…”
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Urinary Excretion of N‑Nitroso Compounds in Rats Fed Sodium Nitrite and/or Hot Dogs by Zhou, Lin, Anwar, Muhammad M, Zahid, Muhammad, Shostrom, Valerie, Mirvish, Sidney S

“…Nitrite-treated meat is a reported risk factor for colon cancer. Mice that ingested sodium nitrite (NaNO2) or hot dogs (a nitrite-treated product) showed…”
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The etiology of gastric cancer. Intragastric nitrosamide formation and other theories by Mirvish, S S

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Nitrosation of Glycine Ethyl Ester and Ethyl Diazoacetate To Give the Alkylating Agent and Mutagen Ethyl Chloro(hydroximino)acetate by Zhou, Lin, Haorah, James, Chen, Sheng C, Wang, Xiaojie, Kolar, Carol, Lawson, Terence A, Mirvish, Sidney S

“…Whereas nitrosation of secondary amines produces nitrosamines, amino acids with primary amino groups and glycine ethyl ester were reported to react with…”
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Depentylation of the Rat Esophageal Carcinogen, Methyl-n-pentylnitrosamine, by Microsomes from Various Human and Rat Tissues and by Cytochrome P450 2A3 by Chen, S C, Zhou, L, Ding, X, Mirvish, S S

“…Methyl- n -pentylnitrosamine (MPN) is carcinogenic for the rat esophagus. To determine organ specificity for MPN activation by human tissues, microsomes…”
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Suggestive evidence for the induction of colonic aberrant crypts in mice fed sodium nitrite by Zhou, Lin, Zahid, Muhammad, Anwar, Muhammad M., Pennington, Karen L., Cohen, Samuel M., Wisecarver, James L., Shostrom, Valerie, Mirvish, Sidney S.

“…A reported linkage between processed (nitrite-treated) meat products and the incidence of colon cancer could be due to sodium nitrite (NaNO 2 ) itself or to…”
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Calcium inhibits promotion by hot dog of 1,2‐dimethylhydrazine‐induced mucin‐depleted foci in rat colon by Santarelli, Raphaelle L., Naud, Nathalie, Taché, Sylviane, Guéraud, Françoise, Vendeuvre, Jean‐Luc, Zhou, Lin, Anwar, Muhammad M., Mirvish, Sidney S., Corpet, Denis E., Pierre, Fabrice H.F.

“…Epidemiology suggests that processed meat is associated with colorectal cancer risk, but few experimental studies support this association. We have shown that…”
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