Search Results - "Mirnics, Zeljka Korade"

Novel CLCN1 mutations with unique clinical and electrophysiological consequences by Wu, Fen‐Fen, Ryan, Aisling, Devaney, Joseph, Warnstedt, Maike, Korade‐Mirnics, Zeljka, Poser, Barbara, Escriva, Maria Jose, Pegoraro, Elena, Yee, Audrey S., Felice, Kevin J., Giuliani, Michael J., Mayer, Richard F., Mongini, Tiziana, Palmucci, Laura, Marino, Michael, Rüdel, Reinhardt, Hoffman, Eric P., Fahlke, Christoph

“…Myotonia is a condition characterized by impaired relaxation of muscle following sudden forceful contraction. We systematically screened all 23 exons of the…”
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Src kinase-mediated signaling in leukocytes by Korade-Mirnics, Željka, Corey, Seth J

“…A concert of antigens, antibodies, cytokines, adhesion molecules, lipid factors, and their different receptors mediate leukocyte development and inflammatory…”
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P75 neurotrophin receptor regulates expression of neural cell adhesion molecule 1 by Mirnics, Zeljka Korade, Yan, Chaohua, Portugal, Carmel, Kim, Tae-Wan, Saragovi, H. Uri, Sisodia, Sangram S., Mirnics, Karoly, Schor, Nina F.

“…Our recent transcriptome profiling studies suggest that presenilin 1 (PS1) regulates expression of neural cell adhesion molecule (Ncam1) through p75…”
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Bcl-2 mediates induction of neural differentiation by YE LIANG, MIMICS, Zeljka Korade, CHAOHUA YAN, NYLANDER, Karen D, SCHOR, Nina Felice

“…Bcl-2 is an antiapoptotic protein expressed in a wide variety of cell types. We have found that overexpression of bcl-2 in PC12 neural crest tumor cells leads…”
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Myotonic dystrophy: Molecular windows on a complex etiology by Korade-Mirnics, Zeljka, Hoffman, Eric, Babitzke, Paul

“…Myotonic dystrophy (DM) is the most common form of adult onset muscular dystrophy, with an incidence of ∼1 in 8500 adults. DM is caused by an expanded number…”
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Bcl-2-mediated potentiation of neocarzinostatin-induced apoptosis : requirement for caspase-3, sulfhydryl groups, and cleavable Bcl-2 by ZHIPING MI, HONG, Borah, MIMICS, Zeljka Korade, TYURINA, Yulia Y, KAGAN, Valerian E, YE LIANG, SCHOR, Nina Felice

“…Overexpression of antiapoptotic Bcl-2 family members is thought to contribute to chemotherapeutic resistance of neural crest tumors. Paradoxical potentiation…”
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Environmental Enrichment Reduces Aβ Levels and Amyloid Deposition in Transgenic Mice by Lazarov, Orly, Robinson, John, Tang, Ya-Ping, Hairston, Ilana S., Korade-Mirnics, Zeljka, Lee, Virginia M.-Y., Hersh, Louis B., Sapolsky, Robert M., Mirnics, Karoly, Sisodia, Sangram S.

“…Cerebral deposition of β-amyloid (Aβ) peptides is an invariant pathological hallmark in brains of patients with Alzheimer’s disease (AD) and transgenic mice…”
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p75NTR-dependent modulation of cellular handling of reactive oxygen species by Mi, Zhiping, Rogers, Danny A, Mirnics, Zeljka Korade, Schor, Nina Felice

“…Our previous studies demonstrated that p75NTR confers protection against oxidative stress-induced apoptosis upon PC12 cells; however, the mechanisms…”
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Bcl-2 overexpression disrupts the morphology of PC12 cells through reduced ERK activation by Mi, Zhiping, Mirnics, Zeljka Korade, Schor, Nina Felice

“…Bcl-2 has been hypothesized to regulate many cellular functions in addition to its well-characterized role in the prevention of programmed cell death. To…”
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The intracellular domain of p75NTR as a determinant of cellular reducing potential and response to oxidant stress by Tyurina, Yulia Y., Nylander, Karen D., Mirnics, Zeljka Korade, Portugal, Carmel, Yan, Chaohua, Zaccaro, Clara, Saragovi, H. Uri, Kagan, Valerian E., Schor, Nina F.

“…Summary The low‐affinity neurotrophin receptor, p75NTR, has been found to be pro‐ or anti‐apoptotic depending upon the cell in which it is expressed. Reactive…”
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P4-277 The role of PS1 in P75 signaling by Mirnics, Zeljka Korade, Yan, Chaohua, Portugal, Carmel, Mirnics, Karoly, Sisodia, Sangram S., Schor, Nina F.

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Microarray Analysis of Lyn-Deficient B Cells Reveals Germinal Center-Associated Nuclear Protein and Other Genes Associated with the Lymphoid Germinal Center by Mirnics, Zeljka Korade, Caudell, Eva, Gao, YanHua, Kuwahara, Kazuhiko, Sakaguchi, Nobuo, Kurosaki, Tomohiro, Burnside, Joan, Mirnics, Karoly, Corey, Seth J

“…Lyn is the only member of the Src family expressed in DT40 B cells, which provide a unique model to study the singular contribution of this protein tyrosine…”
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Dna microarray analysis of g-csf dependent, lyn-dependent genes by Korade-Mirnics, Zeljka, Burnside, Joan, Corey, Seth

“…We have developed a model to study the singular contribution of a Src kinase to cytokine receptor signaling. The DT40 B cell line expresses only one, Lyn, of…”
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Environmental enrichment reduces Abeta levels and amyloid deposition in transgenic mice by Lazarov, Orly, Robinson, John, Tang, Ya-Ping, Hairston, Ilana S, Korade-Mirnics, Zeljka, Lee, Virginia M-Y, Hersh, Louis B, Sapolsky, Robert M, Mirnics, Karoly, Sisodia, Sangram S

“…Cerebral deposition of beta-amyloid (Abeta) peptides is an invariant pathological hallmark in brains of patients with Alzheimer's disease (AD) and transgenic…”
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P4-266 Brain transcriptome changes in presenilin-1 mutant mice by Mirnics, Karoly, Mirnics, Zeljka Korade, Portugal, Carmel F., Terrano, David, Lazarov, Orly, Douglass, Katherine C., Lewis, David A., Schor, Nina F., Sisodia, Sangram S.

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Myotonic dystrophy: tissue-specific effect of somatic CTG expansions on allele-specific DMAHP/SIX5 expression by Korade-Mirnics, Z, Tarleton, J, Servidei, S, Casey, R R, Gennarelli, M, Pegoraro, E, Angelini, C, Hoffman, E P

“…Myotonic dystrophy (DM), the most common inherited muscle disorder, is caused by a CTG expansion in the 3"-untranslated region of a protein kinase gene ( DMPK…”
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Identification of the Presenilins in Hematopoietic Cells with Localization of Presenilin 1 to Neutrophil and Platelet Granules by Mirnics, Zeljka Korade, Calafat, Jero, Udby, Lene, Lovelock, Josh, Kjeldsen, Lars, Rothermund, Kristi, Sisodia, Sangram S., Borregaard, Niels, Corey, Seth J.

“…ABSTRACT Most cases of familial Alzheimer disease (AD) are caused by mutations in presenilin 1 (PS1) and presenilin 2 (PS2). Presenilins are required for the…”
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Cholesterol biosynthesis and the pro-apoptotic effects of the p75 nerve growth factor receptor in PC12 pheochromocytoma cells by Yan, Chaohua, Mirnics, Zeljka Korade, Portugal, Carmel F., Liang, Ye, Nylander, Karen D., Rudzinski, Marcelo, Zaccaro, Clara, Saragovi, H. Uri, Schor, Nina Felice

“…Neocarzinostatin (NCS), an enediyne antimitotic agent, induces cell death in both p75NTR neurotrophin receptor (NTR)-positive and p75NTR-negative PC12 cells in…”
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Myotonic Dystrophy: Tissue-Specific Effect of Somatic CTG Expansions on Allele-Specific DMAPH/SIX5 Expression by Korade-Mirnics, Zeljka, Tarleton, Jack, Servidei, Serenella, Casey, Renee R., Gennarelli, Massimo, Pegoraro, Elena, Angelini, Corrado, Hoffman, Eric P.

“…Myotonic dystrophy (DM), the most common inherited muscle disorder, is caused by a CTG expansion in the 3′-untranslated region of a protein kinase gene (DMPK)…”
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