Search Results - "Mirkina, I"

Midostaurin (PKC412) inhibits immunoglobulin E-dependent activation and mediator release in human blood basophils and mast cells by Krauth, M.-T., Mirkina, I., Herrmann, H., Baumgartner, C., Kneidinger, M., Valent, P.

“…Summary Background KIT tyrosine kinase inhibitors (TKI), such as nilotinib or midostaurin (PKC412), are increasingly used in clinical trials to counteract…”
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CD203c is overexpressed on neoplastic mast cells in systemic mastocytosis and is upregulated upon IgE receptor cross-linking by Hauswirth, A W, Escribano, L, Prados, A, Nuñez, R, Mirkina, I, Kneidinger, M, Florian, S, Sonneck, K, Vales, A, Schernthaner, G-H, Sanchez-Muñoz, L, Sperr, W R, Bühring, H-J, Orfao, A, Valent, P

“…The ectoenzyme E-NPP3 (CD203c) has recently been identified as a novel activation-linked cell surface antigen on basophils. In the present study, we examined…”
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P-263 ON203: A new antibody targeting the oxidized form of macrophage migration inhibitory factor demonstrates antitumorigenic activity and TME modulation in patient-derived CRC tumoroids by Maurer, B., Mirkina, I., Thiele, M.

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ON203: A new antibody targeting the oxidized form of macrophage migration inhibitory factor demonstrates antitumorigenic activity in preclinical models by Schinagl, A., Maurer, B., Rossmüller, G., Mirkina, I., Landlinger, C., Thiele, M.

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The Differentially Spliced Mouse tagL Gene, Homolog of tag7/PGRP Gene Family in Mammals and Drosophila, can Recognize Gram-positive and Gram-negative Bacterial Cell Wall Independently of T Phage Lysozyme Homology Domain by Kibardin, A.V., Mirkina, I.I., Baranova, E.V., Zakeyeva, I.R., Georgiev, G.P., Kiselev, S.L.

“…Tag7/PGRP, a recently characterized antimicrobial protein, is conserved from insects to mammals. Recently its involvement in Toll signalling in Drosophila was…”
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Tumor Cell Cytolysis Mediated by Valorphin, an Opioid-Like Fragment of Hemoglobin β-Chain by Blishchenko, Elena Yu, Mernenko, Olga A, Mirkina, Irina I, Satpaev, Daulet K, Ivanov, Vadim S, Tchikin, Leonid D, Ostrovsky, Andrey G, Karelin, Andrey A, Ivanov, Vadim T

“…Blishchenko, E. Yu., O. A. Mernenko, I. I. Mirkina, D. K. Satpaev, V. S. Ivanov, L. D. Tchikin, A. G. Ostrovsky, A. A. Karelin and V. T. Ivanov. Tumor cell…”
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Expression analysis of proteins encoded by genes of the tag7/tagL (PGRP-S,L) family in human peripheral blood cells by Kibardin, A V, Mirkina, I I, Zakeeva, I R, Baranova, E V, Georgiev, G P, Kiselev, S L

“…Various types of human blood cells were tested for expression of the Tag7/PGRP-SA and TagL/PGRP-L proteins, which belong to the family of proteins possessing…”
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Molecular cloning of a new mouse gene tagL containing a lysozyme-like domain by Kibardin, A V, Mirkina, I I, Korneeva, E A, Gnuchev, N V, Georgiev, G P, Kiselev, S L

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Cytotoxic activity of acetylcholine receptor ligands by Blishchenko, E.Yu, Mirkina, I. I., Mernenko, O. A., Yatskin, O. N., Satpaev, D. K., Strizhkov, B. N., Karelin, A. A.

“…Acetylcholine receptor ligands were studied for cytotoxicity in K562 human erythroid leukemia tumor cells. Cytotoxicity of carbachol, an agonist of…”
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Different pathways of the release of cytotoxic proteins in LAK cells by Sashchenko, L.P., Lukyanova, T.I., Kabanova, O.D., Mirkina, I., Yatskin, O.N., Pongor, S., Gnuchev, N.V.

“…Human LAK cells were shown to release cytotoxic proteins by both Ca 2+-dependent and Ca 2+-independent mechanisms. CD3 + CD8 + CD16 − and CD16 + CD8 + CD3 −…”
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Met-enkephalin induces cytolytic processes of apoptotic type in K562 human erythroid leukemia cells by Mernenko, Olga A., Blishchenko, Elena Yu, Mirkina, Irina I., Karelin, Andrey A.

“…Cytolytic activity of Met-enkephalin, an endogenous opioid peptide, was studied within the 10 −7−10 −17 M concentration range in K562 human erythroid leukemia…”
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Inhibition of human cord blood-derived mast cell responses by anti-Fc approximately equal to RI mAb 15/1 versus anti-IgE Omalizumab by Mirkina, I, Schweighoffer, T, Kricek, F

“…Aggregation of the alpha -chain of the high affinity IgE receptor (Fc approximately equal to RI alpha ) on mast cells or basophils after cross-linking of…”
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Polo-like kinase-1 as a novel target in neoplastic mast cells: demonstration of growth-inhibitory effects of small interfering RNA and the Polo-like kinase-1 targeting drug BI 2536 by PETER, Barbara, GLEIXNER, Karoline V, PICKL, Winfried F, MÜLLAUER, Leonhard, WILLMANN, Michael, VALENT, Peter, CERNY-REITERER, Sabine, HERRMANN, Harald, WINTER, Viviane, HADZIJUSUFOVIC, Emir, FERENC, Veronika, SCHUCH, Karina, MIRKINA, Irina, HORNY, Hans-Peter

“…In advanced systemic mastocytosis the response of neoplastic mast cells to conventional drugs is poor and the prognosis is bad. Current research is, therefore,…”
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Cytolytic processes induced by TNF in L929 and K562 differ in DNA fragmentation mechanisms by Mirkina, Irina I., Mernenko, Olga A., Satpaev, Daulet K., Karelin, Andrey A., Blishchenko, Elena Yu

“…Objective: Cytolytic activity of TNF was analysed at L929 and K562 tumor cell lines. Methods: TNF-mediated cytotoxicity was studied within 10 −6-10 −17 M…”
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Cloning and study of novel mammalian genes with structural homology with phage lysozyme by Mirkina, I I, Kibardin, A V, Korneeva, E A, Gnuchev, N V, Georgiev, G P, Kiselev, S L

“…The mouse tag7 gene was cloned and characterized in our previous works. This work is devoted to identifying and cloning its homologs. The human homolog of the…”
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Cloning the human tag7 gene and study of its genomic organization by Mirkina, I I, Kiselev, S L, Sashchenko, L P, Sadchikova, E R, Gnuchev, N V

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Effect of granular serine proteases and protein kinases on cytolytic activity of lymphokine-activated killers by Sashchenko, L P, Luk'ianova, T I, Mirkina, I I, Pongor, S, Gnuchev, N V

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Tag7-immunoreactive cytotoxic protein is produced by human LAK cells by Mirkina, I I, Kiselev, S L, Dukhanina, E A, Luk'ianova, T I, Shatalov, Iu, Sashchenko, L P, Gnuchev, N V

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Cytotoxic proteins in LAK cells induce apoptotic and necrotic processes in target cells by Sashchenko, L P, Luk'ianova, T I, Mirkina, I I, Kabanova, O D, Pongor, S, Gnuchev, N V

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Metothyrin therapy of patients with thyrotoxicosis by GOL'DBERG, G A, MIRKINA, Iu A

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