Search Results - "Miri, Andrew"

Behaviorally Selective Engagement of Short-Latency Effector Pathways by Motor Cortex by Miri, Andrew, Warriner, Claire L., Seely, Jeffrey S., Elsayed, Gamaleldin F., Cunningham, John P., Churchland, Mark M., Jessell, Thomas M.

“…Blocking motor cortical output with lesions or pharmacological inactivation has identified movements that require motor cortex. Yet, when and how motor cortex…”
Get full text

Spinal Inhibitory Interneuron Diversity Delineates Variant Motor Microcircuits by Bikoff, Jay B., Gabitto, Mariano I., Rivard, Andre F., Drobac, Estelle, Machado, Timothy A., Miri, Andrew, Brenner-Morton, Susan, Famojure, Erica, Diaz, Carolyn, Alvarez, Francisco J., Mentis, George Z., Jessell, Thomas M.

“…Animals generate movement by engaging spinal circuits that direct precise sequences of muscle contraction, but the identity and organizational logic of local…”
Get full text

Regression-based identification of behavior-encoding neurons during large-scale optical imaging of neural activity at cellular resolution by Miri, Andrew, Daie, Kayvon, Burdine, Rebecca D, Aksay, Emre, Tank, David W

“…The advent of methods for optical imaging of large-scale neural activity at cellular resolution in behaving animals presents the problem of identifying…”
Get full text

Prolonged, brain-wide expression of nuclear-localized GCaMP3 for functional circuit mapping by Kim, Christina K, Miri, Andrew, Leung, Louis C, Berndt, Andre, Mourrain, Philippe, Tank, David W, Burdine, Rebecca D

“…Larval zebrafish offer the potential for large-scale optical imaging of neural activity throughout the central nervous system; however, several barriers…”
Get full text

All-trans-retinal shuts down rod cyclic nucleotide-gated ion channels: A novel role for photoreceptor retinoids in the response to bright light? by Dean, Dylan M, Nguitragool, Wang, Miri, Andrew, McCabe, Sarah L, Zimmerman, Anita L

“…In retinal rods, light-induced isomerization of 11- cis -retinal to all- trans -retinal within rhodopsin triggers an enzyme cascade that lowers the…”
Get full text

Motor cortical influence relies on task-specific activity covariation by Warriner, Claire L., Fageiry, Samaher, Saxena, Shreya, Costa, Rui M., Miri, Andrew

“…During limb movement, spinal circuits facilitate the alternating activation of antagonistic flexor and extensor muscles. Yet antagonist cocontraction is often…”
Get full text

Primacy of Flexor Locomotor Pattern Revealed by Ancestral Reversion of Motor Neuron Identity by Machado, Timothy A., Pnevmatikakis, Eftychios, Paninski, Liam, Jessell, Thomas M., Miri, Andrew

“…Spinal circuits can generate locomotor output in the absence of sensory or descending input, but the principles of locomotor circuit organization remain…”
Get full text

Spatial gradients and multidimensional dynamics in a neural integrator circuit by Aksay, Emre, Tank, David W, Miri, Andrew, Daie, Kayvon, Arrenberg, Aristides B, Baier, Herwig

“…The authors measure the time constant of decay of persistent firing (persistence time) across a population of larval zebrafish oculomotor velocity-to-position…”
Get full text

Towards Cell and Subtype Resolved Functional Organization: Mouse as a Model for the Cortical Control of Movement by Warriner, Claire L., Fageiry, Samaher K., Carmona, Lina M., Miri, Andrew

“…•In this review, we consider the mouse as a model for studying the functional organization of motor cortex.•Technical limits have historically precluded…”
Get full text

Oculomotor plant and neural dynamics suggest gaze control requires integration on distributed timescales by Miri, Andrew, Bhasin, Brandon J., Aksay, Emre R. F., Tank, David W., Goldman, Mark S.

“…A fundamental principle of biological motor control is that the neural commands driving movement must conform to the response properties of the motor plants…”
Get full text

Edging toward Entelechy in Motor Control by Miri, Andrew, Azim, Eiman, Jessell, Thomas M.

“…The organization and functional logic of corticospinal motor neurons and their target connections remains unclear, despite their evident influence on movement…”
Get full text

Motor Cortex Embeds Muscle-like Commands in an Untangled Population Response by Russo, Abigail A., Bittner, Sean R., Perkins, Sean M., Seely, Jeffrey S., London, Brian M., Lara, Antonio H., Miri, Andrew, Marshall, Najja J., Kohn, Adam, Jessell, Thomas M., Abbott, Laurence F., Cunningham, John P., Churchland, Mark M.

“…Primate motor cortex projects to spinal interneurons and motoneurons, suggesting that motor cortex activity may be dominated by muscle-like commands…”
Get full text

A Dynamical Feedback Model for Adaptation in the Olfactory Transduction Pathway by De Palo, Giovanna, Boccaccio, Anna, Miri, Andrew, Menini, Anna, Altafini, Claudio

“…Olfactory transduction exhibits two distinct types of adaptation, which we denote multipulse and step adaptation. In terms of measured transduction current,…”
Get full text

All-trans-retinal is a closed-state inhibitor of rod cyclic nucleotide-gated ion channels by McCabe, Sarah L, Pelosi, Diana M, Tetreault, Michelle, Miri, Andrew, Nguitragool, Wang, Kovithvathanaphong, Pranisa, Mahajan, Rahul, Zimmerman, Anita L

“…Rod vision begins when 11-cis-retinal absorbs a photon and isomerizes to all-trans-retinal (ATR) within the photopigment, rhodopsin. Photoactivated rhodopsin…”
Get full text

All-trans-Retinal Shuts Down Rod Cyclic Nucleotidegated Ion Channels: A Novel Role for Photoreceptor Retinoids in the Response to Bright Light? by Dean, Dylan M., Nguitragool, Wang, Miri, Andrew, McCabe, Sarah L., Zimmerman, Anita L.

“…In retinal rods, light-induced isomerization of 11-cis-retinal to all-trans-retinal within rhodopsin triggers an enzyme cascade that lowers the concentration…”
Get full text

Multidimensional Firing Rate Dynamics in a Neural Integrator by Miri, Joseph Andrew

“…The neural mechanisms underlying short-term memory remain largely unknown. The horizontal velocity-to-position neural integrator (hVPNI) is a compelling model…”
Get full text