Search Results - "Mirarab, Siavash"
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Fast Coalescent-Based Computation of Local Branch Support from Quartet Frequencies
Published in Molecular biology and evolution (01-07-2016)“…Species tree reconstruction is complicated by effects of incomplete lineage sorting, commonly modeled by the multi-species coalescent model (MSC). While there…”
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TreeShrink: fast and accurate detection of outlier long branches in collections of phylogenetic trees
Published in BMC genomics (08-05-2018)“…Sequence data used in reconstructing phylogenetic trees may include various sources of error. Typically errors are detected at the sequence level, but when…”
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ASTRAL-III: polynomial time species tree reconstruction from partially resolved gene trees
Published in BMC bioinformatics (08-05-2018)“…Evolutionary histories can be discordant across the genome, and such discordances need to be considered in reconstructing the species phylogeny. ASTRAL is one…”
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Precise phylogenetic analysis of microbial isolates and genomes from metagenomes using PhyloPhlAn 3.0
Published in Nature communications (19-05-2020)“…Microbial genomes are available at an ever-increasing pace, as cultivation and sequencing become cheaper and obtaining metagenome-assembled genomes (MAGs)…”
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ASTRAL-Pro: Quartet-Based Species-Tree Inference despite Paralogy
Published in Molecular biology and evolution (01-11-2020)“…Abstract Phylogenetic inference from genome-wide data (phylogenomics) has revolutionized the study of evolution because it enables accounting for discordance…”
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ASTRAL-MP: scaling ASTRAL to very large datasets using randomization and parallelization
Published in Bioinformatics (15-10-2019)“…Abstract Motivation Evolutionary histories can change from one part of the genome to another. The potential for discordance between the gene trees has…”
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TreeCluster: Clustering biological sequences using phylogenetic trees
Published in PloS one (22-08-2019)“…Clustering homologous sequences based on their similarity is a problem that appears in many bioinformatics applications. The fact that sequences cluster is…”
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Forcing external constraints on tree inference using ASTRAL
Published in BMC genomics (16-04-2020)“…To account for genome-wide discordance among gene trees, several widely-used methods seek to find a species tree with the minimum distance to input gene trees…”
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DiscoVista: Interpretable visualizations of gene tree discordance
Published in Molecular phylogenetics and evolution (01-05-2018)“…[Display omitted] •We introduce a new tool, DiscoVista, for phylogenomic visualization of discordance.•DiscoVista helps systematists to generate interpretable…”
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Minimum variance rooting of phylogenetic trees and implications for species tree reconstruction
Published in PloS one (11-08-2017)“…Phylogenetic trees inferred using commonly-used models of sequence evolution are unrooted, but the root position matters both for interpretation and downstream…”
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Phylogenetic Placement of Exact Amplicon Sequences Improves Associations with Clinical Information
Published in mSystems (01-05-2018)“…Recent algorithmic advances in amplicon-based microbiome studies enable the inference of exact amplicon sequence fragments. These new methods enable the…”
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Weighted Statistical Binning: Enabling Statistically Consistent Genome-Scale Phylogenetic Analyses
Published in PloS one (18-06-2015)“…Because biological processes can result in different loci having different evolutionary histories, species tree estimation requires multiple loci from across…”
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Phylogenomic species tree estimation in the presence of incomplete lineage sorting and horizontal gene transfer
Published in BMC genomics (02-10-2015)“…Species tree estimation is challenged by gene tree heterogeneity resulting from biological processes such as duplication and loss, hybridization, incomplete…”
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A comparative study of SVDquartets and other coalescent-based species tree estimation methods
Published in BMC genomics (02-10-2015)“…Species tree estimation is challenging in the presence of incomplete lineage sorting (ILS), which can make gene trees different from the species tree. Because…”
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Statistical binning enables an accurate coalescent-based estimation of the avian tree
Published in Science (American Association for the Advancement of Science) (12-12-2014)“…Gene tree incongruence arising from incomplete lineage sorting (ILS) can reduce the accuracy of concatenation-based estimations of species trees. Although…”
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Median quartet tree search algorithms using optimal subtree prune and regraft
Published in Algorithms for molecular biology (13-03-2024)“…Gene trees can be different from the species tree due to biological processes and inference errors. One way to obtain a species tree is to find one that…”
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Skmer: assembly-free and alignment-free sample identification using genome skims
Published in Genome Biology (13-02-2019)“…The ability to inexpensively describe taxonomic diversity is critical in this era of rapid climate and biodiversity changes. The recent genome-skimming…”
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Anchoring quartet-based phylogenetic distances and applications to species tree reconstruction
Published in BMC genomics (11-11-2016)“…Inferring species trees from gene trees using the coalescent-based summary methods has been the subject of much attention, yet new scalable and accurate…”
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Phylogenomics of 10,575 genomes reveals evolutionary proximity between domains Bacteria and Archaea
Published in Nature communications (02-12-2019)“…Rapid growth of genome data provides opportunities for updating microbial evolutionary relationships, but this is challenged by the discordant evolution of…”
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Greengenes2 unifies microbial data in a single reference tree
Published in Nature biotechnology (01-05-2024)“…Studies using 16S rRNA and shotgun metagenomics typically yield different results, usually attributed to PCR amplification biases. We introduce Greengenes2, a…”
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