Search Results - "Miranda, Maricar"

The Angiopoietin-like Proteins ANGPTL3 and ANGPTL4 Inhibit Lipoprotein Lipase Activity through Distinct Mechanisms by Shan, Lu, Yu, Xuan-Chuan, Liu, Ziye, Hu, Yi, Sturgis, Lydia T., Miranda, Maricar L., Liu, Qingyun

“…Two members of the angiopoietin-like family of proteins, ANGPTL3 and ANGPTL4, have been shown to play important roles in modulating lipoprotein metabolism in…”
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Molecular characterization and identification of surrogate substrates for diacylglycerol lipase α by Pedicord, Donna L., Flynn, Michael J., Fanslau, Caroline, Miranda, Maricar, Hunihan, Lisa, Robertson, Barbara J., Pearce, Bradley C., Yu, Xuan-Chuan, Westphal, Ryan S., Blat, Yuval

“…► Identified the catalytic triad of DAGLα. ► Demonstrated that DAGLα C-terminal domain is not needed for catalysis. ► Identified chromogenic and fluorogenic…”
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Novel potent inhibitors of deoxycytidine kinase identified and compared by multiple assays by Yu, Xuan-Chuan, Miranda, Maricar, Liu, Ziye, Patel, Shiv, Nguyen, Nghi, Carson, Kenneth, Liu, Qingyun, Swaffield, Jonathan C

“…Deoxycytidine kinase (dCK) phosphorylates deoxycytidine, deoxyguanosine, and deoxyadenosine and plays an important role in the salvage pathway of nucleoside…”
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Lead optimization and structure-based design of potent and bioavailable deoxycytidine kinase inhibitors by Jessop, Theodore C., Tarver, James E., Carlsen, Marianne, Xu, Amy, Healy, Jason P., Heim-Riether, Alexander, Fu, Qinghong, Taylor, Jerry A., Augeri, David J., Shen, Min, Stouch, Terry R., Swanson, Ronald V., Tari, Leslie W., Hunter, Michael, Hoffman, Isaac, Keyes, Philip E., Yu, Xuan-Chuan, Miranda, Maricar, Liu, Qingyun, Swaffield, Jonathan C., David Kimball, S., Nouraldeen, Amr, Wilson, Alan G.E., Foushee, Ann Marie DiGeorge, Jhaver, Kanchan, Finch, Rick, Anderson, Steve, Oravecz, Tamas, Carson, Kenneth G.

“…A series of deoxycytidine kinase inhibitors was simultaneously optimized for potency and PK properties. A co-crystal structure then allowed merging this series…”
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5-Fluorocytosine derivatives as inhibitors of deoxycytidine kinase by Tarver, James E., Jessop, Theodore C., Carlsen, Marianne, Augeri, David J., Fu, Qinghong, Healy, Jason P., Heim-Riether, Alexander, Xu, Amy, Taylor, Jerry A., Shen, Min, Keyes, Philip E., David Kimball, S., Yu, Xuan-Chuan, Miranda, Maricar, Liu, Qingyun, Swaffield, Jonathan C., Nouraldeen, Amr, Wilson, Alan G.E., Finch, Rick, Jhaver, Kanchan, Foushee, Ann Marie DiGeorge, Anderson, Steve, Oravecz, Tamas, Carson, Kenneth G.

“…A series of potent piperidine-linked cytosine derivatives were prepared as inhibitors of deoxycytidine kinase (dCK). Compound 9h was discovered to be a potent…”
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Phenotypic changes in Arabidopsis caused by expression of a yeast vacuolar Ca2+/H+ antiporter by Hirschi, K D, Miranda, M L, Wilganowski, N L

“…In plants, cytosolic Ca2+ levels are tightly regulated, and changes in cytosolic Ca2+ have been implicated in converting numerous signals into adapted…”
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