Search Results - "Miranda, Lucas Antonio Ferreira"

Physicochemical Characterization and Skin Permeation of Cationic Transfersomes Containing the Synthetic Peptide PnPP-19 by De Marco Almeida, Flavia, Silva, Carolina Nunes, de Araujo Lopes, Savia Caldeira, Santos, Daniel Moreira, Torres, Fernanda Silva, Cardoso, Felipe Lima, Martinelli, Patricia Massara, da Silva, Elizabeth Ribeiro, de Lima, Maria Elena, Miranda, Lucas Antonio Ferreira, Oliveira, Monica Cristina

“…PnPP-19 is a 19-amino-acid synthetic peptide previously described as a novel drug for the treatment of erectile dysfunction. The aim of this work was to…”
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Recent progress in micro and nano-encapsulation of bioactive derivatives of the Brazilian genus Pterodon by de Alcantara Lemos, Janaina, Oliveira, Anna Eliza M.F.M., Araujo, Raquel Silva, Townsend, Danyelle M., Ferreira, Lucas Antonio Miranda, de Barros, Andre Luis Branco

“…In the last few decades, utilization of medicinal plants by the pharmaceutical industry has led to the identification of many new bioactive compounds. The…”
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Alpha-tocopheryl succinate and doxorubicin-loaded liposomes improve drug uptake and tumor accumulation in a murine breast tumor model by Boratto, Fernanda A., Lages, Eduardo B., Loures, Cristina M.C., Sabino, Adriano P., Malachias, Angelo, Townsend, Danyelle M., Branco De Barros, Andre Luis, Miranda Ferreira, Lucas Antonio, Amaral Leite, Elaine

“…Liposomes composed of a rigid bilayer have high plasma stability; however, they can be challenged in efficacy due to complications in releasing the…”
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Reductions in Skin and Systemic Parasite Burdens as a Combined Effect of Topical Paromomycin and Oral Miltefosine Treatment of Mice Experimentally Infected with Leishmania (Leishmania) amazonensis by GONTIJO AGUIAR, Marta, MACHADO PEREIRA, Aline Márcia, FERNANDES, Ana Paula, MIRANDA FERREIRA, Lucas Antonio

“…Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Co-delivery of doxorubicin, docosahexaenoic acid, and α-tocopherol succinate by nanostructured lipid carriers has a synergistic effect to enhance antitumor activity and reduce toxicity by Lages, Eduardo Burgarelli, Fernandes, Renata Salgado, Silva, Juliana de Oliveira, de Souza, Ângelo Malachias, Cassali, Geovanni Dantas, de Barros, André Luís Branco, Miranda Ferreira, Lucas Antônio

“…[Display omitted] •Design of a novel nanostructured lipid carriers (NLC) formulation loading DOX, DHA, and TS.•Hydrophobic ion-pairing with TS allows high DOX…”
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Hyaluronic acid-coated nanoemulsions loaded with a hydrophobic ion pair of all-trans retinoic acid for improving the anticancer activity by Tinoco, Letícia Márcia da Silva, Silva, Flávia Lidiane Oliveira da, Ferreira, Lucas Antônio Miranda, Leite, Elaine Amaral, Carneiro, Guilherme

“…All-trans retinoic acid (ATRA) has been studied for the treatment of cancer, including leukemia and breast cancer. This work aims to develop nanoemulsions (NE)…”
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Triphenylmethane derivatives have high in vitro and in vivo activity against the main causative agents of cutaneous leishmaniasis by de Souza Pietra, Renata Celi Carvalho, Rodrigues, Lucas Fonseca, Teixeira, Eliane, Fried, Levi, Lefkove, Benjamin, Rabello, Ana, Arbiser, Jack, Ferreira, Lucas Antônio Miranda, Fernandes, Ana Paula

“…The current standard of care for cutaneous leishmaniasis (CL) is organic antimonial compounds, but the administration of these compounds is complicated by a…”
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Formation of ion pairing as an alternative to improve encapsulation and anticancer activity of all-trans retinoic acid loaded in solid lipid nanoparticles by Carneiro, Guilherme, Silva, Elton Luiz, Pacheco, Layssa Alves, de Souza-Fagundes, Elaine Maria, Corrêa, Natássia Caroline Resende, de Goes, Alfredo Miranda, de Oliveira, Mônica Cristina, Ferreira, Lucas Antônio Miranda

“…This work aims to develop solid lipid nanoparticles (SLNs) loaded with retinoic acid (RA) to evaluate the influence of two lipophilic amines, stearylamine (SA)…”
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Nanoencapsulated retinoic acid as a safe tolerogenic adjuvant for intranasal vaccination against cutaneous leishmaniasis by Bezerra, Izabella P.S., Costa-Souza, Beatriz L.S., Carneiro, Guilherme, Ferreira, Lucas Antonio Miranda, de Matos Guedes, Herbert Leonel, Rossi-Bergmann, Bartira

“…Mucosal, but not peripheral, vaccination with whole Leishmania amazonensis antigen (LaAg) effectively protects mice against leishmaniasis, likely through a…”
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Preclinical evaluation of L-fucoside from lapachol-loaded nanoemulsion as a strategy to breast cancer treatment by Miranda, Sued Eustaquio Mendes, de Alcantara Lemos, Janaina, Ottoni, Flaviano Melo, Cassali, Geovanni Dantas, Townsend, Danyelle M., de Aguiar Ferreira, Carolina, Alves, Ricardo Jose, Ferreira, Lucas Antonio Miranda, de Barros, Andre Luis Branco

“…Breast cancer prevails as the most common cancer in women, underscoring an urgent need for more effective therapies. This study explores the potential of our…”
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Enhanced antitumor efficacy of lapachol-loaded nanoemulsion in breast cancer tumor model by Mendes Miranda, Sued Eustáquio, Alcântara Lemos, Janaína de, Fernandes, Renata Salgado, Silva, Juliana de Oliveira, Ottoni, Flaviano M., Townsend, Danyelle M., Rubello, Domenico, Alves, Ricardo José, Cassali, Geovanni Dantas, Ferreira, Lucas Antônio Miranda, de Barros, Andre Luis Branco

“…[Display omitted] •The encapsulation of lapachol increased the blood circulation and tumor uptake.•Lapachol-loaded nanoemulsion therapy reduced the tumor…”
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Drug delivery systems for the topical treatment of cutaneous leishmaniasis by Carneiro, Guilherme, Aguiar, Marta Gontijo, Fernandes, Ana Paula, Ferreira, Lucas Antônio Miranda

“…The parenteral administration of pentavalent antimonials for the treatment of all forms of leishmaniasis, including cutaneous leishamniasis (CL), has several…”
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Doxorubicin-loaded pH-sensitive micelles: A promising alternative to enhance antitumor activity and reduce toxicity by Cavalcante, Carolina Henriques, Fernandes, Renata Salgado, de Oliveira Silva, Juliana, Ramos Oda, Caroline Mari, Leite, Elaine Amaral, Cassali, Geovanni Dantas, Charlie-Silva, Ives, Ventura Fernandes, Bianca Helena, Miranda Ferreira, Lucas Antônio, de Barros, Andre Luis Branco

“…[Display omitted] •Preparation, and characterization of pH-sensitive micelle composed of DSPE-PEG2000, oleic acid, and DOX.•The utilization of oleic acid is…”
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pH-sensitive doxorubicin-tocopherol succinate prodrug encapsulated in docosahexaenoic acid-based nanostructured lipid carriers: An effective strategy to improve pharmacokinetics and reduce toxic effects by Lages, Eduardo Burgarelli, Fernandes, Renata Salgado, Andrade, Marina Mol Sena, Paiyabhroma, Nitchawat, de Oliveira, Renata Barbosa, Fernandes, Christian, Cassali, Geovanni Dantas, Sicard, Pierre, Richard, Sylvain, Branco de Barros, André Luís, Ferreira, Lucas Antônio Miranda

“…Side effects often limit the use of doxorubicin (DOX) in cancer treatment. We have recently developed a nanostructured lipid carrier (NLC) formulation for…”
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Alendronate-coated long-circulating liposomes containing [sup.99m]technetium-ceftizoxime used to identify osteomyelitis by Ferreira, Diego dos Santos, Boratto, Fernanda Alves, Cardoso, Valbert Nascimento, Serakides, Rogeria, Fernandes, Zimone Odilia, Ferreira, Lucas Antonio Miranda, Oliveira, Monica Cristina

“…Osteomyelitis is a progressive destruction of bones caused by microorganisms. Inadequate or absent treatment increases the risk of bone growth inhibition,…”
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4-Chlorophenylthioacetone-derived thiosemicarbazones as potent antitrypanosomal drug candidates: Investigations on the mode of action by Rodney Rodrigues de Assis, Diego, Almeida Oliveira, Alexandre, Luiz Porto, Samuel, Aparecida Nonato Rabelo, Rayane, Burgarelli Lages, Eduardo, Corrêa Santos, Viviane, Marques Milagre, Matheus, Perdigão Fragoso, Stenio, Martins Teixeira, Mauro, Salgado Ferreira, Rafaela, Renato Machado, Carlos, Antônio Miranda Ferreira, Lucas, Lucio Speziali, Nivaldo, Beraldo, Heloisa, Simão Machado, Fabiana

“…[Display omitted] •Thiophenol-2-ylidene-thiosemicarbazones tested against Trypanosoma cruzi (Tc).•The compounds possess potent trypanocidal capacity in vitro…”
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Improved In Vitro Antileukemic Activity of All-Trans Retinoic Acid Loaded in Cholesteryl Butyrate Solid Lipid Nanoparticles by Silva, Elton Luiz, Lima, Flávia Alves, Carneiro, Guilherme, Ramos Jonas Periera, Gomes, Dawidson Assis, de Souza-Fagundes, Elaine Maria, Ferreira, Lucas Antônio Miranda

“…All-trans retinoic acid, a hydrophobic drug, has become one of the most successful examples of differentiation agents used for treatment of acute promyelocytic…”
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Nanomedicine in Oncocardiology: Contribution and Perspectives of Preclinical Studies by Borges, Gabriel Silva Marques, Lages, Eduardo Burgarelli, Sicard, Pierre, Ferreira, Lucas Antônio Miranda, Richard, Sylvain

“…Cancer and cardiovascular diseases are the leading causes of death and morbidity worldwide. Strikingly, cardiovascular disorders are more common and more…”
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Development of a bone-targeted pH-sensitive liposomal formulation containing doxorubicin: physicochemical characterization, cytotoxicity, and biodistribution evaluation in a mouse model of bone metastasis by Ferreira, Diêgo Dos Santos, Faria, Samilla Dornelas, Lopes, Sávia Caldeira de Araújo, Teixeira, Cláudia Salviano, Malachias, Angelo, Magalhães-Paniago, Rogério, de Souza Filho, José Dias, Oliveira, Bruno Luis de Jesus Pinto, Guimarães, Alexander Ramos, Caravan, Peter, Ferreira, Lucas Antônio Miranda, Alves, Ricardo José, Oliveira, Mônica Cristina

“…Despite recent advances in cancer therapy, the treatment of bone tumors remains a major challenge. A possible underlying hypothesis, limitation, and unmet need…”
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Combined suboptimal schedules of topical paromomycin, meglumine antimoniate and miltefosine to treat experimental infection caused by Leishmania (Viannia) braziliensis by de Morais-Teixeira, Eliane, Aguiar, Marta Gontijo, Soares de Souza Lima, Bruna, Ferreira, Lucas Antônio Miranda, Rabello, Ana

“…This study aimed to evaluate the efficacy of binary combinations of suboptimal schedules of drugs with different administration routes (topical paromomycin,…”
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