Chronic pain after hospital discharge on patients hospitalized for COVID-19: an observational study

There are few studies related to Coronavirus Disease 2019 (COVID-19) on the prevalence and nature of pain symptoms after hospital discharge, especially in individuals who develop moderate to severe disease forms. Therefore, this study aimed to evaluate the presence of chronic pain in patients discha...

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Bibliographic Details
Published in:	Brazilian journal of anesthesiology (Elsevier) Vol. 74; no. 4; p. 744457
Main Authors:	Moreira de Barros, Guilherme Antonio, Silva, Douglas Inomata Cardoso da, Barbosa, Mariana Lopes Amaral, Soares, Rafael Abbud, Alves, Rodrigo Leal, Miranda, Claudio Lucas, Costa, Paula Danieli Lopes da, Nascimento Júnior, Paulo do, Módolo, Norma Sueli Pinheiro
Format:	Journal Article
Language:	English
Published:	Brazil Elsevier España S.L.U 01-07-2024 Elsevier
Subjects:	Adult Aged Chronic pain Chronic Pain - epidemiology Chronic Pain - etiology COVID-19 COVID-19 - complications COVID-19 - epidemiology Cross-Sectional Studies Female Hospitalization Humans Male Middle Aged Obesity - complications Obesity - epidemiology Patient Discharge Post-COVID syndrome Post-intensive care syndrome Prevalence Risk Factors SARS-CoV-2 Severity of Illness Index Sex Factors Survivors COVID-19 Post-intensive care syndrome SARS-CoV-2 Post-COVID syndrome Chronic pain Survivors
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Summary:	There are few studies related to Coronavirus Disease 2019 (COVID-19) on the prevalence and nature of pain symptoms after hospital discharge, especially in individuals who develop moderate to severe disease forms. Therefore, this study aimed to evaluate the presence of chronic pain in patients discharged after hospitalization for COVID-19, and the relationship between the presence of chronic pain and intensive care stay, demographics, and risk factors for the worst Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) outcome. A cross-sectional observational study was carried out on patients with COVID-19 who recovered after hospitalization. Patients were recruited at the least 3 months after discharge and their hospital's health files were prospected. The variables evaluated were demographics, the severity of SARS-CoV-2 infection (considering the need for intensive care), and the presence of chronic pain. The results were shown in a descriptive manner, and multivariate analysis expressed as Odds Ratios (ORs) and respective Confidence Intervals (CIs) for the outcomes studied. Statistical significance was set at p < 0.05. Of 242 individuals included, 77 (31.8%) reported chronic pain related to COVID-19, with no correlation with the severity of infection. Female sex and obesity were associated with a higher risk for chronic pain with ORs of 2.69 (Confidence Interval [95% CI 1.4 to 5.0]) and 3.02 (95% CI 1.5 to 5.9). The limbs were the most affected areas of the body. Chronic pain is common among COVID-19 survivors treated in hospital environments. Female sex and obesity are risk factors for its occurrence.
ISSN:	0104-0014 0104-0014 2352-2291
DOI:	10.1016/j.bjane.2023.08.001