Search Results - "Miranda, Ana Cláudia"
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Radiochemical and biological properties of peptides designed to interact with EGF receptor: Relevance for glioblastoma
Published in Nuclear medicine and biology (01-09-2020)“…Radiolabeled peptides with high specificity to receptors expressed on tumor cells hold a great promise as diagnostic and therapeutic tracers. The main…”
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Radiosynthesis Standardization and Preclinical Assessment of the [68Ga]Ga-DOTA-Ubiquicidin29-41: A Translational Study Targeting Differential Diagnosis of Infectious Processes
Published in Pharmaceuticals (Basel, Switzerland) (01-01-2024)“…Human bacterial infections significantly contribute to the increase in healthcare-related burdens. This scenario drives the study of novel techniques for the…”
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Standardization of the [ 68 Ga]Ga-PSMA-11 Radiolabeling Protocol in an Automatic Synthesis Module: Assessments for PET Imaging of Prostate Cancer
Published in Pharmaceuticals (Basel, Switzerland) (21-04-2021)“…Prostate-specific membrane antigen (PSMA) is a glycoprotein present in the prostate, that is overexpressed in prostate cancer (PCa). Recently, PSMA-directed…”
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A new model of experimental hemispherotomy in young adult Rattus norvegicus: a neural tract tracing and SPECT in vivo study
Published in Journal of neurosurgery (01-04-2019)“…The objective of this study was to describe a new experimental model of hemispherotomy performed on laboratory animals. Twenty-six male young adult Wistar rats…”
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Comparative Evaluation of Radiochemical and Biological Properties of 131I- and [99mTc]Tc(CO)3-Labeled RGD Analogues Planned to Interact with the αvβ3 Integrin Expressed in Glioblastoma
Published in Pharmaceuticals (Basel, Switzerland) (18-01-2022)“…Radiolabeled peptides with high specificity for overexpressed receptors in tumor cells hold great promise for diagnostic and therapeutic applications. In this…”
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Kinetic modeling of 68Ga-PSMA-11 and validation of simplified methods for quantification in primary prostate cancer patients
Published in EJNMMI research (24-02-2020)“…Background The positron emission tomography (PET) ligand 68 Ga-Glu-urea-Lys(Ahx)-HBED-CC ( 68 Ga-PSMA-11) targets the prostate-specific membrane antigen…”
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Radioimmunotheranostic Pair Based on the Anti-HER2 Monoclonal Antibody: Influence of Chelating Agents and Radionuclides on Biological Properties
Published in Pharmaceutics (27-06-2021)“…The oncogene HER2 is an important molecular target in oncology because it is associated with aggressive disease and the worst prognosis. The development of…”
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Comparative overview of innovation and patent filings in Radiopharmacy
Published in Einstein (São Paulo, Brazil) (01-01-2020)“…To expose the current situation of the Brazilian Nuclear Medicine in relation to innovation, taking into account the Intellectual Property protection and the…”
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Assessment of bioactive peptides derived from laminin-111 as prospective breast cancer-targeting agents
Published in Amino acids (29-01-2024)“…Breast cancer remains a pressing public health issue primarily affecting women. Recent research has spotlighted bioactive peptides derived from laminin-111,…”
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Determination of fexofenadine in Hank's balanced salt solution by high-performance liquid chromatography with ultraviolet detection: application to Caco-2 cell permeability studies
Published in Biomedical chromatography (01-04-2015)“…The drug‐transporting proteins can affect the pharmacokinetics and pharmacodymanics of many drugs, resulting in an erratic and unpredictable pharmacological…”
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Anti-HER2 monoclonal antibody based-radioimmunoconjugates: Assessment of the chelating agent influence
Published in Bioorganic & medicinal chemistry (01-03-2021)“…[Display omitted] •RICs were evaluated regarding the influence of the bifunctional chelators (BFCs).•Physical-chemical parameters and HER2 tumor cell binding…”
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The water-soluble non-starch polysaccharides from bananas display immunomodulatory properties on cultured macrophages
Published in Food research international (01-09-2016)“…Some diet components, such as certain indigestible polysaccharides from edible plants, may interact with the gut-associated lymphoid tissue and improve the…”
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13
Sensory remapping: a possible therapy option
Published in Medicina (Sao Paulo. 197?) (14-04-2023)“…The human sensory receptors are morphologically specialized to transduce specific stimuli into the brain. However, when an injury occurs, mainly in the spinal…”
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Non-AIDS-related comorbidities in people living with HIV-1 aged 50 years and older: The AGING POSITIVE study
Published in International journal of infectious diseases (01-02-2019)“…•A high prevalence of non-AIDS-related comorbidities (NARC) was found in Portuguese HIV-infected patients ≥50 years old.•The most common NARC were metabolic,…”
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Remdesivir and corticosteroids in the treatment of hospitalized COVID-19 patients
Published in Scientific reports (18-03-2023)“…Coronavirus disease 2019 (COVID-19) is a pandemic infection caused by the newly discovered severe acute respiratory syndrome coronavirus 2. Remdesivir (RDV)…”
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Radiochemical and biological assessments of a PSMA-I&S cold kit for fast and inexpensive 99mTc-labeling for SPECT imaging and radioguided surgery in prostate cancer
Published in Frontiers in chemistry (12-10-2023)“…The expression of prostate-specific membrane antigen (PSMA) is upregulated in prostate cancer (PCa) cells and PSMA-ligands have been radiolabeled and used as…”
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Comparative Study of Two Oxidizing Agents, Chloramine T and Iodo-Gen ® , for the Radiolabeling of β-CIT with Iodine-131: Relevance for Parkinson's Disease
Published in Pharmaceuticals (Basel, Switzerland) (05-02-2019)“…Parkinson's disease (PD) is a neurodegenerative disease characterized by the loss of dopaminergic neurons in the , leading to alteration of the integrity of…”
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Mycobacterium chelonae cutaneous infection: An opportunistic disease in an immunosuppressed patient with myasthenia gravis
Published in IDCases (01-01-2020)“…•Mycobacterium chelonae infection may occur in chronic treatment with steroids.•The most common presentation form is disseminated cutaneous…”
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LGBTQI+: conceitos e definições aplicados no contexto da saúde
Published in Psi logos : revista do Serviço de Psiquiatria do Hospital Fernando Fonseca (29-12-2023)“…Introdução: A Organização Mundial de Saúde e a comunidade médica têm vindo a reconhecer a necessidade de intervir nos grupos considerados como minorias sexuais…”
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Real-World Characterization of the Portuguese Population Living with HIV who Initiated Raltegravir Based-Regimens: The REALITY Study
Published in Acta médica portuguesa (01-07-2022)“…Introduction: Although raltegravir has been available since 2007, data are lacking on the Portuguese population living with HIV who initiated this…”
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