Search Results - "Miracle, Ann L."

Transcription of Key Genes Regulating Gonadal Steroidogenesis in Control and Ketoconazole- or Vinclozolin-Exposed Fathead Minnows by Villeneuve, Daniel L., Blake, Lindsey S., Brodin, Jeffrey D., Greene, Katie J., Knoebl, Iris, Miracle, Ann L., Martinovic, Dalma, Ankley, Gerald T.

“…This study evaluated changes in the expression of steroidogenesis-related genes in male fathead minnows exposed to ketoconazole (KTC) or vinclozolin (VZ) for…”
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Ecotoxicogenomics: linkages between exposure and effects in assessing risks of aquatic contaminants to fish by Miracle, Ann L., Ankley, Gerald T.

“…Understanding the biological effects of exposures to chemicals in the environment relies on classical methods and emerging technologies in the areas of…”
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Complex expression patterns of lymphocyte-specific genes during the development of cartilaginous fish implicate unique lymphoid tissues in generating an immune repertoire by Miracle, Ann L., Anderson, Michele K., Litman, Ronda T., Walsh, Cathy J., Luer, Carl A., Rothenberg, Ellen V., Litman, Gary W.

“…Cartilaginous fish express canonical B and T cell recognition genes, but their lymphoid organs and lymphocyte development have been poorly defined. Here, the…”
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Toxicogenomics in Regulatory Ecotoxicology by Ankley, Gerald T, Daston, George P, Degitz, Sigmund J, Denslow, Nancy D, Hoke, Robert A, Kennedy, Sean W, Miracle, Ann L, Perkins, Edward J, Snape, Jason, Tillitt, Donald E, Tyler, Charles R, Versteeg, Donald

“…Powerful new genomic techniques could significantly change how regulators evaluate contaminants. However, many practical and conceptual challenges remain…”
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Members of the Ikaros Gene Family Are Present in Early Representative Vertebrates by Haire, Robert N, Miracle, Ann L, Rast, Jonathan P, Litman, Gary W

“…Members of the Ikaros multigene family of zinc finger proteins are expressed in a tissue-specific manner and most are critical determinants in the development…”
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Evolution of Hematopoiesis: Three Members of the PU.1 Transcription Factor Family in a Cartilaginous Fish, Raja eglanteria by Anderson, Michele K., Sun, Xiao, Miracle, Ann L., Litman, Gary W., Rothenberg, Ellen V.

“…T lymphocytes and B lymphocytes are present in jawed vertebrates, including cartilaginous fishes, but not in jawless vertebrates or invertebrates. The origins…”
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A Graphical Systems Model to Facilitate Hypothesis-Driven Ecotoxicogenomics Research on the Teleost Brain−Pituitary−Gonadal Axis by Villeneuve, Daniel L, Larkin, Patrick, Knoebl, Iris, Miracle, Ann L, Kahl, Michael D, Jensen, Kathleen M, Makynen, Elizabeth A, Durhan, Elizabeth J, Carter, Barbara J, Denslow, Nancy D, Ankley, Gerald T

“…Graphical systems models are powerful tools that can help facilitate hypothesis-driven ecotoxicogenomic research and aid in mechanistic interpretation of…”
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Growth inhibition and stimulation of Shewanella oneidensis MR-1 by surfactants and calcium polysulfide by Bailey, Kathryn L., Tilton, Fred, Jansik, Danielle P., Ergas, Sarina J., Marshall, Matthew J., Miracle, Ann L., Wellman, Dawn M.

“…Foam delivery technology (FDT) uses surfactant based foam to immobilize subsurface contaminants in situ. Where traditional approaches are impractical, FDT has…”
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Development and validation of a 2,000-gene microarray for the fathead minnow (Pimephales promelas) by Larkin, P, Villeneuve, D.L, Knoebl, I, Miracle, A.L, Carter, B.J, Liu, L, Denslow, N.D, Ankley, G.T

“…Gene microarrays provide the field of ecotoxicology new tools to identify mechanisms of action of chemicals and chemical mixtures. Herein we describe the…”
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Investigating freshwater periphyton community response to uranium with phospholipid fatty acid and denaturing gradient gel electrophoresis analyses by Small, Jack A., Bunn, Amoret, McKinstry, Craig, Peacock, Aaron, Miracle, Ann L.

“…Periphyton communities can be used as monitors of ecosystem health and as indicators of contamination in lotic systems. Measures of biomass, community…”
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Evolutionary Origins of Lymphocytes: Ensembles of T Cell and B Cell Transcriptional Regulators in a Cartilaginous Fish by Anderson, Michele K, Pant, Rashmi, Miracle, Ann L, Sun, Xiao, Luer, Carl A, Walsh, Catherine J, Telfer, Janice C, Litman, Gary W, Rothenberg, Ellen V

“…The evolutionary origins of lymphocytes can be traced by phylogenetic comparisons of key features. Homologs of rearranging TCR and Ig (B cell receptor) genes…”
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Development of quantitative real-time PCR assays for fathead minnow ( Pimephales promelas) gonadotropin β subunit mRNAs to support endocrine disruptor research by Villeneuve, Daniel L., Miracle, Ann L., Jensen, Kathleen M., Degitz, Sigmund J., Kahl, Michael D., Korte, Joseph J., Greene, Katie J., Blake, Lindsey S., Linnum, Ann L., Ankley, Gerald T.

“…Fathead minnows ( Pimephales promelas) are a widely-used small fish model for regulatory ecotoxicology testing and research related to endocrine disrupting…”
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Extraordinary Variation in a Diversified Family of Immune-Type Receptor Genes by Hawke, Noel A., Yoder, Jeffrey A., Haire, Robert N., Mueller, M. Gail, Litman, Ronda T., Miracle, Ann L., Stuge, Tor, Shen, Linling, Miller, Norman, Litman, Gary W.

“…Immune inhibitory receptor genes that encode a variable (V) region, a unique V-like C2 (V/C2) domain, a transmembrane region, and a cytoplasmic tail containing…”
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17α-ethynylestradiol-induced vitellogenin gene transcription quantified in livers of adult males, larvae, and gills of fathead minnows (Pimephales promelas) by Lattier, David L., Reddy, Tirumuru V., Gordon, Denise A., Lazorchak, James M., Smith, Mark E., Williams, Daniel E., Wiechman, Barry, Flick, Robert W., Miracle, Ann L., Toth, Gregory P.

“…We have applied a method for quantifying relative levels of messenger RNA (mRNA) transcription to assess chemically induced gene expression in fathead minnows…”
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A Novel Multigene Family Encodes Diversified Variable Regions by Strong, Scott J., Mueller, M. Gail, Litman, Ronda T., Hawke, Noel A., Haire, Robert N., Miracle, Ann L., Rast, Jonathan P., Amemiya, Chris T., Litman, Gary W.

“…Antigen recognition in the adaptive immune response by lg and T-cell antigen receptors (TCRs) is effected through patterned differences in the peptide sequence…”
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The path from molecular indicators of exposure to describing dynamic biological systems in an aquatic organism: microarrays and the fathead minnow by Miracle, Ann L, Toth, Gregory P, Lattier, David L

“…The extent to which humans and wildlife are exposed to toxicants is an important focus of environmental research. This work has been directed toward the…”
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Terminal deoxynucleotidyl transferases from elasmobranchs reveal structural conservation within vertebrates by Bartl, Simona, Miracle, Ann L, Rumfelt, Lynn L, Kepler, Thomas B, Mochon, Evonne, Litman, Gary W, Flajnik, Martin F

“…The DNA polymerase (pol) X family is an ancient group of enzymes that function in DNA replication and repair (pol beta), translesion synthesis (pol lambda and…”
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Expression of two vitellogenin genes ( vg1 and vg3) in fathead minnow ( Pimephales promelas) liver in response to exposure to steroidal estrogens and androgens by Miracle, Ann, Ankley, Gerald, Lattier, David

“…In this study, we describe the sequence for the fathead minnow ( Pimephales promelas) vitellogenin 3 gene ( vg3) and compare the responses of vg1 and vg3…”
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Altered gene expression in the brain and liver of female fathead minnows Pimephales promelas Rafinesque exposed to fadrozole by Villeneuve, D. L., Knoebl, I., Larkin, P., Miracle, A. L., Carter, B. J., Denslow, N. D., Ankley, G. T.

“…The fathead minnow Pimephales promelas is a small fish species widely used for ecotoxicology research and regulatory testing in North America. This study used…”
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Ecotoxicogenomics: linkages between exposure and effects in assessing risks of aquatic contaminants to fish: Systems biology/Computational toxicology by MIRACLE, Ann L, ANKLEY, Gerald T

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