Search Results - "Mira, Portia M"
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Rational design of antibiotic treatment plans: a treatment strategy for managing evolution and reversing resistance
Published in PloS one (06-05-2015)“…The development of reliable methods for restoring susceptibility after antibiotic resistance arises has proven elusive. A greater understanding of the…”
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Correction: Rational Design of Antibiotic Treatment Plans: A Treatment Strategy for Managing Evolution and Reversing Resistance
Published in PloS one (24-09-2015)Get full text
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Adaptive Landscapes of Resistance Genes Change as Antibiotic Concentrations Change
Published in Molecular biology and evolution (01-10-2015)“…Most studies on the evolution of antibiotic resistance are focused on selection for resistance at lethal antibiotic concentrations, which has allowed the…”
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Adaptive Processes Change as Multiple Functions Evolve
Published in Antimicrobial agents and chemotherapy (18-03-2021)“…Epistasis influences the gene-environment interactions that shape bacterial fitness through antibiotic exposure, which can ultimately affect the availability…”
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Trichomonas vaginalis extracellular vesicles up-regulate and directly transfer adherence factors promoting host cell colonization
Published in Proceedings of the National Academy of Sciences - PNAS (18-06-2024)“…, a common sexually transmitted parasite that colonizes the human urogenital tract, secretes extracellular vesicles (TvEVs) that are taken up by human cells…”
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Understanding the Impacts of Sub-inhibitory Concentrations and Clinical Use of Beta-lactam Antibiotics on the Evolution of Beta-lactamase Resistance Genes
Published 01-01-2018“…Antibiotic resistance continues to be a major challenge we face today. Scientists and medical professionals are competing against a microbial evolutionary time…”
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Dissertation -
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Rational Design of Antibiotic Treatment Plans
Published 05-06-2014“…The development of reliable methods for restoring susceptibility after antibiotic resistance arises has proven elusive. A greater understanding of the…”
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Journal Article