Search Results - "Mira, C"

Concise Review: Embryonic Stem Cells Versus Induced Pluripotent Stem Cells: The Game Is On by Puri, Mira C., Nagy, Andras

“…Extraordinary advances in pluripotent stem cell research have initiated an era of hope for regenerative strategies to treat human disease. Besides embryonic…”
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Structural and Functional Framework for the Autoinhibition of Nedd4-Family Ubiquitin Ligases by Mari, Sara, Ruetalo, Natalia, Maspero, Elena, Stoffregen, Mira C., Pasqualato, Sebastiano, Polo, Simona, Wiesner, Silke

“…Nedd4-family ubiquitin ligases are key regulators of cell surface receptor signaling. Their dysregulation is associated with several human diseases, including…”
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Sepsis Pathophysiology, Chronic Critical Illness, and Persistent Inflammation-Immunosuppression and Catabolism Syndrome by Mira, Juan C., Gentile, Lori F., Mathias, Brittany J., Efron, Philip A., Brakenridge, Scott C., Mohr, Alicia M., Moore, Frederick A., Moldawer, Lyle L.

“…OBJECTIVES:To provide an appraisal of the evolving paradigms in the pathophysiology of sepsis and propose the evolution of a new phenotype of critically ill…”
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Interferon stimulation creates chromatin marks and establishes transcriptional memory by Kamada, Rui, Yang, Wenjing, Zhang, Yubo, Patel, Mira C., Yang, Yanqin, Ouda, Ryota, Dey, Anup, Wakabayashi, Yoshiyuki, Sakaguchi, Kazuyasu, Fujita, Takashi, Tamura, Tomohiko, Zhu, Jun, Ozato, Keiko

“…Epigenetic memory for signal-dependent transcription has remained elusive. So far, the concept of epigenetic memory has been largely limited to…”
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Cell competition during reprogramming gives rise to dominant clones by Shakiba, Nika, Fahmy, Ahmed, Jayakumaran, Gowtham, McGibbon, Sophie, David, Laurent, Trcka, Daniel, Elbaz, Judith, Puri, Mira C, Nagy, Andras, van der Kooy, Derek, Goyal, Sidhartha, Wrana, Jeffrey L, Zandstra, Peter W

“…The ability to generate induced pluripotent stem cells from differentiated cell types has enabled researchers to engineer cell states. Although studies have…”
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Global update on the susceptibilities of human influenza viruses to neuraminidase inhibitors and the cap-dependent endonuclease inhibitor baloxavir, 2018–2020 by Govorkova, Elena A., Takashita, Emi, Daniels, Rod S., Fujisaki, Seiichiro, Presser, Lance D., Patel, Mira C., Huang, Weijuan, Lackenby, Angie, Nguyen, Ha T., Pereyaslov, Dmitriy, Rattigan, Aine, Brown, Sook Kwan, Samaan, Magdi, Subbarao, Kanta, Wong, Sun, Wang, Dayan, Webby, Richard J., Yen, Hui-Ling, Zhang, Wenqing, Meijer, Adam, Gubareva, Larisa V.

“…Global analysis of the susceptibility of influenza viruses to neuraminidase (NA) inhibitors (NAIs) and the polymerase acidic (PA) inhibitor (PAI) baloxavir was…”
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Incomplete Differentiation of Engrafted Bone Marrow Endothelial Progenitor Cells Initiates Hepatic Fibrosis in the Rat by Maretti‐Mira, Ana C., Wang, Xiangdong, Wang, Lei, DeLeve, Laurie D.

“…Normal liver sinusoidal endothelial cells (LSECs) promote quiescence of hepatic stellate cells (HSCs). Prior to fibrosis, LSECs undergo capillarization, which…”
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The structure of the ubiquitin-like modifier FAT10 reveals an alternative targeting mechanism for proteasomal degradation by Aichem, Annette, Anders, Samira, Catone, Nicola, Rößler, Philip, Stotz, Sophie, Berg, Andrej, Schwab, Ricarda, Scheuermann, Sophia, Bialas, Johanna, Schütz-Stoffregen, Mira C., Schmidtke, Gunter, Peter, Christine, Groettrup, Marcus, Wiesner, Silke

“…FAT10 is a ubiquitin-like modifier that directly targets proteins for proteasomal degradation. Here, we report the high-resolution structures of the two…”
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Liver‐Selective MMP‐9 Inhibition in the Rat Eliminates Ischemia‐Reperfusion Injury and Accelerates Liver Regeneration by Wang, Xiangdong, Maretti‐Mira, Ana C., Wang, Lei, DeLeve, Laurie D.

“…Recruitment of liver sinusoidal endothelial cell progenitor cells (sprocs) from the bone marrow by vascular endothelial growth factor‐stromal cell‐derived…”
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BRD4 Coordinates Recruitment of Pause Release Factor P-TEFb and the Pausing Complex NELF/DSIF To Regulate Transcription Elongation of Interferon-Stimulated Genes by Patel, Mira C., Debrosse, Maxime, Smith, Matthew, Dey, Anup, Huynh, Walter, Sarai, Naoyuki, Heightman, Tom D., Tamura, Tomohiko, Ozato, Keiko

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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CD73-Deficient Mice Are Resistant to Carcinogenesis by STAGG, John, BEAVIS, Paul A, DIVISEKERA, Upulie, LIU, Mira C. P, MÖLLER, Andreas, DARCY, Phillip K, SMYTH, Mark J

“…CD73 is a cell surface 5'-nucleotidase that converts AMP to adenosine, an immune suppressive molecule. CD73 may promote immune escape in cancer by contributing…”
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Multicountry Spread of Influenza A(H1N1)pdm09 Viruses with Reduced Oseltamivir Inhibition, May 2023-February 2024 by Patel, Mira C, Nguyen, Ha T, Pascua, Philippe Noriel Q, Gao, Rongyuan, Steel, John, Kondor, Rebecca J, Gubareva, Larisa V

“…Since May 2023, a novel combination of neuraminidase mutations, I223V + S247N, has been detected in influenza A(H1N1)pdm09 viruses collected in countries…”
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The WW1 Domain Enhances Autoinhibition in Smurf Ubiquitin Ligases by Ruetalo, Natalia, Anders, Samira, Stollmaier, Carsten, Jäckl, Magnus, Schütz-Stoffregen, Mira C., Stefan, Nadine, Wolf, Christine, Wiesner, Silke

“…Downregulation of ubiquitin (Ub) ligase activity prevents premature ubiquitination and is critical for cellular homeostasis. Nedd4 Ub ligases share a common…”
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Assessing baloxavir susceptibility of influenza viruses circulating in the United States during the 2016/17 and 2017/18 seasons by Gubareva, Larisa V, Mishin, Vasiliy P, Patel, Mira C, Chesnokov, Anton, Nguyen, Ha T, De La Cruz, Juan, Spencer, Sarah, Campbell, Angela P, Sinner, Mallory, Reid, Heather, Garten, Rebecca, Katz, Jackie M, Fry, Alicia M, Barnes, John, Wentworth, David E

“…The anti-influenza therapeutic baloxavir targets cap-dependent endonuclease activity of polymerase acidic (PA) protein. We monitored baloxavir susceptibility…”
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Susceptibility of Rat Steatotic Liver to Ischemia–Reperfusion Is Treatable With Liver‐Selective Matrix Metalloproteinase Inhibition by Wang, Xiangdong, Walkey, Christopher J., Maretti‐Mira, Ana C., Wang, Lei, Johnson, Deborah L., DeLeve, Laurie D.

“…Background and Aims This study examined whether enhanced susceptibility of steatotic liver to ischemia–reperfusion (I/R) injury is due to impaired recruitment…”
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TLR4 antagonist FP7 inhibits LPS-induced cytokine production and glycolytic reprogramming in dendritic cells, and protects mice from lethal influenza infection by Perrin-Cocon, Laure, Aublin-Gex, Anne, Sestito, Stefania E., Shirey, Kari Ann, Patel, Mira C., André, Patrice, Blanco, Jorge C., Vogel, Stefanie N., Peri, Francesco, Lotteau, Vincent

“…Dysregulated Toll-like receptor (TLR)-4 activation is involved in acute systemic sepsis, chronic inflammatory diseases, such as atherosclerosis and diabetes,…”
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Susceptibility of Influenza A, B, C, and D Viruses to Baloxavir by Mishin, Vasiliy P, Patel, Mira C, Chesnokov, Anton, De La Cruz, Juan, Nguyen, Ha T, Lollis, Lori, Hodges, Erin, Jang, Yunho, Barnes, John, Uyeki, Timothy, Davis, Charles T, Wentworth, David E, Gubareva, Larisa V

“…Baloxavir showed broad-spectrum in vitro replication inhibition of 4 types of influenza viruses (90% effective concentration range 1.2–98.3 nmol/L);…”
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Efficacy of a respiratory syncytial virus vaccine candidate in a maternal immunization model by Blanco, Jorge C. G., Pletneva, Lioubov M., McGinnes-Cullen, Lori, Otoa, Raymonde O., Patel, Mira C., Fernando, Lurds R., Boukhvalova, Marina S., Morrison, Trudy G.

“…Respiratory syncytial virus (RSV) is the most common cause of bronchiolitis in infants. Maternal immunization is an option to increase maternal antibody levels…”
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UV light perception is modulated by the odour element of an olfactory-visual compound in restrained honeybees by Becker, Mira C, Rössler, Wolfgang, Strube-Bloss, Martin Fritz

“…Honeybees use visual and olfactory cues to detect flowers during foraging trips. Hence, the reward association of a nectar source is a multimodal construct…”
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Persistent Inflammation, Immunosuppression and Catabolism Syndrome by Mira, Juan C., MD, Brakenridge, Scott C., MD, MS, Moldawer, Lyle L., PhD, Moore, Frederick A., MD, MCCM

“…Following advances in critical care, in-hospital multiple organ failure–related mortality is declining. Consequently, incidence of chronic critical illness is…”
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