Search Results - "Mir, Shakeel"
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Inhibition of Autophagic Turnover in β-Cells by Fatty Acids and Glucose Leads to Apoptotic Cell Death
Published in The Journal of biological chemistry (06-03-2015)“…Autophagy, a cellular recycling process responsible for turnover of cytoplasmic contents, is critical for maintenance of health. Defects in this process have…”
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2
Elevated progesterone receptor membrane component 1/sigma-2 receptor levels in lung tumors and plasma from lung cancer patients
Published in International journal of cancer (15-07-2012)“…Cancer is one of the leading causes of death, and there is an urgent need for new biomarkers and therapeutic targets. The progesterone receptor membrane…”
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3
Exploiting Expression of Hippo Effector, Yap, for Expansion of Functional Islet Mass
Published in Molecular endocrinology (Baltimore, Md.) (01-11-2015)“…Loss of pancreas β-cell function is the precipitating factor in all forms of diabetes. Cell replacement therapies, such as islet transplantation, remain the…”
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4
Progesterone receptor membrane component 1/Sigma-2 receptor associates with MAP1LC3B and promotes autophagy
Published in Autophagy (01-10-2013)“…Autophagy resembles a recycling process in which proteins, organelles, or regions of the cytoplasm are enveloped and degraded. We have found that two of the…”
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5
Upregulation of Nox4 induces a pro-survival Nrf2 response in cancer-associated fibroblasts that promotes tumorigenesis and metastasis, in part via Birc5 induction
Published in Breast cancer research : BCR (14-07-2022)“…A pro-oxidant enzyme, NADPH oxidase 4 (Nox4) has been reported to be a critical downstream effector of TGFβ-induced myofibroblast transformation during…”
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6
WS6 induces both alpha and beta cell proliferation without affecting differentiation or viability
Published in ENDOCRINE JOURNAL (2015)“…Agents that stimulate human pancreatic beta cell proliferation are needed to improve diabetes mellitus treatment. Recently, a small molecule, WS6, was observed…”
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Impact of empagliflozin add-on therapy on quality of life in patients of type 2 diabetes mellitus with hypertension: A prospective study
Published in Indian journal of public health (01-11-2022)“…Background: Diabetes has a negative impact on patient's quality of life (QoL). Comorbidities and polypharmacy further worsen their QoL. Thus, in addition to…”
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8
Explicating genetic diversity based on ITS characterization and determination of antioxidant potential in sea buckthorn (Hippophae spp.)
Published in Molecular biology reports (01-06-2022)“…Background Sea buckthorn ( Hippophae ) is in the focus of interest mainly for its positive effects on health of both human and animal organisms. Due to the…”
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9
Neutrophil Gelatinase-associated Lipocalin (NGAL) Expression Is Dependent on the Tumor-associated Sigma-2 Receptor S2RPgrmc1
Published in The Journal of biological chemistry (27-04-2012)“…Tumor invasion is a critical step in the spread of cancer. S2R (sigma-2 receptor)/Pgrmc1 (progesterone receptor membrane component 1) is a cytochrome…”
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10
Relationship between Kinesiophobia, Fall Risk and Activity Level among Elderly Females after Total Knee Arthroplasty
Published in Journal Riphah College of Rehabilitation Sciences (01-12-2022)“…Objective: To determine the effect of Mulligan’s Mobilization on unilateral tibiofemoral osteoarthritis. The objective of the study was to evaluate co-relation…”
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11
Nano-Scale Secondary Ion Mass Spectrometry: A Paradigm Shift in Soil Science
Published in Journal of spectroscopy (Hindawi) (30-04-2024)“…Soils exhibit structural heterogeneity across diverse spatio-temporal scales, yielding myriad of microhabitats, highlighting the need for a nuanced…”
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12
Remediation of lead toxicity with waste-bio materials from aqueous solutions in fixed-bed column using response surface methodology
Published in Heliyon (15-08-2024)“…Heavy metal ions pose significant risks to human health, pelagic, and several other life forms due to perniciousness, tendency to accumulate, and resistance to…”
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13
Development of thiamine-rich snacks from brown rice using extrusion technology
Published in British food journal (1966) (27-04-2021)“…PurposeSnack industry is one of the fastest growing food sectors globally, and people are nowadays conscious about intake of healthy snacks on regular basis…”
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14
Soil microbial and enzyme activities in different land use systems of the Northwestern Himalayas
Published in PeerJ (San Francisco, CA) (26-09-2023)“…Soil microbial activity (SMA) is vital concerning carbon cycling, and its functioning is recognized as the primary factor in modifying soil carbon storage…”
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Soil organic carbon pools and carbon management index under different land use systems in North western Himalayas
Published in PeerJ (San Francisco, CA) (06-06-2023)“…Current study was conducted to evaluate the effect of important land uses and soil depth on soil organic carbon pools viz. total organic carbon, Walkley and…”
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16
Nitrogen-Fixing Cover Crops and Chronosequential Effects on Fertility of Apple Orchard Soils
Published in Agricultural research (India : Online) (01-03-2018)“…The aim of this work was to study the effect of nitrogen-fixing cover crops and chronosequential impact on physical, chemical and biological properties on the…”
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Response of okra (Abelmoschus esculentus) to foliar application of micronutrients
Published in The Indian journal of agricultural sciences (26-07-2021)“…The experiment was conducted at SKUAST-Kashmir, Shalimar during 2018 to evaluate the effects of foliar sprays of different micronutrients, viz. B, Zn Cu, Mo,…”
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18
Analysis of changes in land use and land cover in Central Kashmir of the Great Himalayas using geospatial technologies
Published in Environment conservation journal (01-01-2023)“…Remote sensing data may identify changes in land use and land cover (LU/LC). Land cover changes include changing from one land cover category to another and…”
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Soil carbon dynamics in the temperate Himalayas: Impact of land use management
Published in Frontiers in environmental science (09-12-2022)“…Food security and environmental health are directly linked with soil carbon (C). Soil C plays a crucial role in securing food and livelihood security for the…”
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20
Influence of Anticaking Agents and Storage Conditions on Quality Characteristics of Spray Dried Apricot Powder: Shelf Life Prediction Studies Using Guggenheim-Anderson-de Boer (GAB) Model
Published in Foods (29-12-2022)“…Apricot powder was developed through spray drying using gum arabic as an encapsulating material at a concentration of 19%. Inlet air temperature, feed total…”
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